Hypotension
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CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: Fentanyl Effect on Blood Pressure in Elderly Patients After Induction of General Anesthesia [Phase 2, Phase 3]
Clinical trial update investigating fentanyl's effect on blood pressure in elderly patients after induction of general anesthesia, spanning …
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CLINICAL_TRIALS trial_result · 2019-06-04Clinical Trial Update: Ondansetron in the Prevention of Hypotension in Patients Undergoing Spinal Anesthesia [Phase 4]
A Phase 4 clinical trial assessing whether ondansetron can prevent hypotension in patients receiving spinal anesthesia.
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CLINICAL_TRIALS trial_result · 2019-05-16Clinical Trial Update: Decision Support for Intraoperative Low Blood Pressure [NA]
A completed clinical trial on decision support for intraoperative low blood pressure (hypotension) with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-13Clinical Trial Update: Manging Post Spinal Hypotension During Elective Cesarean Section [Phase 4]
Phase 4 clinical trial update on managing post-spinal hypotension during elective cesarean section has completed.
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CLINICAL_TRIALS trial_result · 2019-03-12Clinical Trial Update: Optimal VAsopressor titraTION Pilot Randomized Controlled Trial [NA]
Pilot randomized controlled trial investigating optimal vasopressor titration for hypotension and shock has completed with results posted.
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FDA approval · 2019-01-31FDA Approved: PHENYLEPHRINE HYDROCHLORIDE — Original Application (Sandoz Inc)
FDA approved an Original Application for Phenylephrine Hydrochloride from Sandoz Inc, enabling the marketing of this generic product.
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FDA approval · 2019-01-29FDA Approved: PHENYLEPHRINE HYDROCHLORIDE — Original Application (Fresenius Kabi USA, LLC)
FDA approved Fresenius Kabi USA, LLC's Original Application for phenylephrine hydrochloride as a generic drug product.
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CLINICAL_TRIALS trial_result · 2019-01-24Clinical Trial Update: A Pilot Analysis of the Association Between Anesthesia Induction Dosing and AKI in the Elderly Population
A completed pilot study from Yale University evaluating whether anesthesia induction dosing is associated with acute kidney injury and hypot…
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FDA approval · 2018-11-07FDA Approved: NOREPINEPHRINE BITARTRATE — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved Hikma Pharmaceuticals USA Inc.'s generic norepinephrine bitartrate injection (Original Application) as a vasopressor for treati…
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CLINICAL_TRIALS trial_result · 2018-10-30Clinical Trial Update: Median Sevoflurane Concentration for Hypotension Between Young and Elderlypatients: Adaptive Clinical Trial [Phase 4]
Phase 4 adaptive trial comparing median sevoflurane concentration for hypotension between young and elderly patients; status and detailed re…
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FDA approval · 2018-10-04FDA Approved: NOREPINEPHRINE BITARTRATE — Original Application (Mylan Institutional LLC)
FDA approved Mylan Institutional LLC's original application for norepinephrine bitartrate injections (generic) as a vasopressor to treat lif…
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FDA approval · 2018-06-12FDA Approved: ISOPROTERENOL — Original Application (Cipla USA Inc.)
FDA approves Cipla's original application for isoproterenol hydrochloride (generic) injection, expanding available generic options.
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: Effect of Granisetron on Usage of Sympathomimetics During Caesarean Section
A completed clinical trial evaluated whether granisetron reduces the need for vasopressor drugs to treat hypotension during cesarean section…
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FDA approval · 2018-04-27FDA Approved: PHENYLEPHRINE HYDROCHLORIDE — Original Application (Meitheal Pharmaceuticals Inc.)
FDA approved Meitheal Pharmaceuticals' phenylephrine hydrochloride product under an Original Application (ANDA 210333).
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CLINICAL_TRIALS research · 2018-03-15Clinical Trial Update: Different Preloads for Prevention of Hypotension in Patients Undergoing Elective CS Under Intrathecal Anesthesia [EARLY_Phase 1]
An early-phase (Phase 1) clinical trial from Assiut University evaluating different preload strategies to prevent hypotension in patients un…
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CLINICAL_TRIALS approval · 2018-03-08Clinical Trial Update: Expanded Access for LJPC-501
La Jolla Pharmaceutical Company's LJPC-501 has been approved for marketing to treat catecholamine-resistant hypotension and distributive sho…
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CLINICAL_TRIALS trial_result · 2018-03-08Clinical Trial Update: A Novel Closed-loop Integrated System for the Maintenance of Haemodynamic Stability [Phase 2, Phase 3]
An update on a novel closed-loop integrated system intended to maintain haemodynamic stability in patients with hypotension, spanning Phase …
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Phenylephrine or Norepinephrine for a Better Hemodynamic Stability [Phase 3]
Phase 3 trial comparing phenylephrine versus norepinephrine for hemodynamic stability in hypotension; study completed.
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CLINICAL_TRIALS trial_result · 2017-10-30Clinical Trial Update: Impact of Music on Satisfaction, Anxiety, and Hemodynamics During Spinal Anesthesia for Cesarean Delivery [NA]
This completed clinical trial evaluated whether listening to music during spinal anesthesia for cesarean delivery affects anxiety, satisfact…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Hypotensive Effect of Anaesthesia With TCI [NA]
Clinical trial NCT02733406 conducted by Umeå University has completed evaluating the hypotensive effects of anesthesia delivered via target-…
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CLINICAL_TRIALS trial_result · 2017-09-13Clinical Trial Update: Determination of Remifentanil's ED50 for Rapid Sequence Intubation Avoiding Bradycardia and Hypotension in Adults [Phase 3]
Phase 3 trial updating the ED50 of remifentanil for rapid sequence intubation to avoid bradycardia and hypotension in adults. Study complete…
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: The Effects of Nicotine Chewing Gum in Parkinson's Disease [NA]
This completed clinical trial from New York Institute of Technology studied nicotine chewing gum in patients with Parkinson's disease; hypot…
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: Oxytocin And Uterotonic Agent Use For Cesarean Delivery [Phase 4]
Phase 4 clinical trial update on using oxytocin and other uterotonic agents during cesarean delivery for patients with uterine atony or hypo…
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: A Comparison of Intermittent Intravenous Boluses of Phenylephrine and Norepinephrine to Prevent Spinal-induced Hypotension in Cesarean Deliveries [NA]
This completed clinical trial compares intermittent IV boluses of phenylephrine versus norepinephrine to prevent spinal anesthesia–induced h…
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: ACEI/ARB Study in Ambulatory and Day of Surgery Admission Patients [NA]
Clinical trial update indicating termination of an ACE inhibitor/ARB study in ambulatory and day-of-surgery admission patients.