Hypopharyngeal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-02-14Clinical Trial Update: NT-I7 for the Treatment of Recurrent Squamous Cell Carcinoma of Head and Neck Undergoing Surgery [Phase 1]
A Phase 1 trial of NT-I7 for recurrent squamous cell carcinoma of the head and neck undergoing surgery was terminated.
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin [Phase 1]
Phase 1 trial evaluating the safety and tolerability of Onalespib in combination with radiation therapy and cisplatin for locoregionally adv…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: A Phase II Study to Evaluate the Efficacy and Safety of Salvage Preoperative PD-1 Inhibitor Combined with Chemotherapy Neoadjuvant Therapy in Recurrent and Metastatic LPSCC/HPSCC [Phase 2]
A Phase II clinical trial is evaluating salvage preoperative PD-1 inhibitor in combination with chemotherapy as neoadjuvant therapy for recu…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Pembrolizumab & Cabozantinib in Patients With Head and Neck Squamous Cell Cancer [Phase 2]
Phase 2 trial evaluating the combination of pembrolizumab and cabozantinib in head and neck squamous cell carcinoma reported results, with r…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports the completion of a study evaluating image-guided proton therapy for locally advanced unresectable head an…
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] [Phase 2]
Phase 2 European Larynx Organ Preservation Study (ELOS) evaluates pembrolizumab (MK-3475) for organ-preserving treatment in squamous cell ca…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer [Phase 1]
Phase 1 trial of nab-paclitaxel (albumin-bound paclitaxel) with carboplatin followed by chemoradiation in patients with recurrent head and n…
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CLINICAL_TRIALS withdrawal · 2024-07-25Clinical Trial Update: Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating Xevinapant added to standard radiation therapy plus cisplatin/carboplatin for head and neck cancers has been withdr…
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CLINICAL_TRIALS trial_result · 2024-04-01Clinical Trial Update: Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery [Phase 2]
A phase 2 trial evaluated the combination of nivolumab with carboplatin and paclitaxel in patients with stage III-IV head and neck squamous …
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CLINICAL_TRIALS trial_result · 2022-12-14Clinical Trial Update: Comparison of Adaptive Dose Painting by Numbers With Standard Radiotherapy for Head and Neck Cancer. [Phase 2]
Phase 2 clinical trial comparing adaptive dose painting by numbers with standard radiotherapy for head and neck cancer has completed.
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CLINICAL_TRIALS trial_result · 2022-01-25Clinical Trial Update: Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck [Phase 2]
This Phase 2 trial evaluated chemotherapy with or without erlotinib in patients with metastatic or recurrent head and neck squamous cell car…
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CLINICAL_TRIALS trial_result · 2020-03-05Clinical Trial Update: Toripalimab in Combination With Chemotherapy as Induced Chemotherapy for Localized Hypopharyngeal Cancer [Phase 2]
Phase 2 trial investigating toripalimab in combination with chemotherapy as induced chemotherapy for localized hypopharyngeal cancer.
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 3]
Phase 3 study evaluating chemotherapy with or without bevacizumab for recurrent or metastatic head and neck squamous cell carcinoma; results…
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CLINICAL_TRIALS trial_result · 2018-11-16Clinical Trial Update: Stereotactic Body Radiation Therapy in Treating Patients With High Risk Locally Advanced Head and Neck Cancer [NA]
A terminated clinical trial evaluating stereotactic body radiation therapy for high-risk locally advanced head and neck cancers; results wer…
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer [Phase 2]
A Phase 2 trial evaluating the combination of capecitabine and vorinostat for recurrent/metastatic head and neck squamous cell carcinomas wa…
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: Phase I Study of IMRT and Molecular-Image Guided Adaptive Radiation Therapy for Advanced HNSCC [Phase 1]
Terminated Phase I trial from Virginia Commonwealth University evaluating IMRT with molecular-image guided adaptive radiation therapy for ad…
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Soy Isoflavones in Preventing Head and Neck Cancer Recurrence in Patients With Stage I-IV Head and Neck Cancer Undergoing Surgery [Phase 2]
Phase 2 clinical trial evaluating whether soy isoflavones can prevent recurrence of head and neck squamous cell carcinomas after surgery; re…
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CLINICAL_TRIALS trial_result · 2016-07-26Clinical Trial Update: Ganetespib Window of Opportunity Study in Head and Neck Cancers [Phase 1]
A Phase 1 window-of-opportunity study of ganetespib in head and neck squamous cell carcinomas has been terminated, involving hypopharyngeal,…
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CLINICAL_TRIALS trial_result · 2015-03-26Clinical Trial Update: Pharmacogenetic Response to Chemotherapy Induction for ORL Cancers
A completed clinical trial evaluated pharmacogenetic responses to induction chemotherapy across head and neck squamous cell carcinomas of th…
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CLINICAL_TRIALS trial_result · 2014-05-29Clinical Trial Update: A Phase II Study of Parotid-gland Sparing IMRT in Patients With Midline Tumour of the Head and Neck
Phase II trial evaluating parotid-gland sparing IMRT for midline head and neck cancers. The study includes patients with oropharyngeal and h…
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CLINICAL_TRIALS trial_result · 2014-02-05Clinical Trial Update: A Phase I/II Study of the Use of Intensity Modulated Radiotherapy (IMRT) in Cancer of the Thyroid, Larynx and Hypopharynx [Phase 1, Phase 2]
A Phase I/II trial evaluating intensity-modulated radiotherapy for locally advanced laryngeal cancer, locally advanced hypopharyngeal squamo…
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CLINICAL_TRIALS trial_result · 2014-01-22Clinical Trial Update: Sunitinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer [Phase 2]
Phase 2 clinical trial evaluating sunitinib for patients with recurrent or metastatic head and neck squamous cell carcinoma, with results po…
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CLINICAL_TRIALS trial_result · 2014-01-07Clinical Trial Update: Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating lapatinib in recurrent and/or metastatic head and neck squamous cell carcinoma (including occult primary cases) has…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Erlotinib Plus Docetaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Head and Neck Cancer [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial evaluating the combination of erlotinib and docetaxel in patients with locally advanced, metastatic, or recur…
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CLINICAL_TRIALS trial_result · 2008-10-10Clinical Trial Update: Laryngeal Preservation in Pyriform Sinus Carcinoma [Phase 2, Phase 3]
A Phase 2/Phase 3 trial investigating laryngeal preservation in pyriform sinus carcinoma has completed. The study concerns hypopharyngeal sq…