Hyperuricemia
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Tophaceous Gout [Phase 2]
A Phase 2 clinical trial update evaluating AR882 alone or in combination with allopurinol for tophaceous gout has completed, focusing on eff…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients with Hyperuricemia [Phase 1, Phase 2]
This open-label PK, PD, and DDI study evaluated dotinurad in combination with allopurinol in gout patients with hyperuricemia and has comple…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Comparative Study Between Febuxostat Versus Vitamin E in Non-alcoholic Steatohepatitis Patients With Hyperuricemia [Phase 2]
Phase 2 clinical trial comparing febuxostat versus vitamin E for non-alcoholic steatohepatitis with hyperuricemia; the study is active but n…
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: The Effect of Allopurinol on the Risk of Cardiovascular Events in Patients with Cardiovascular Risk [Phase 3]
A Phase 3 trial is investigating whether allopurinol reduces cardiovascular events in patients with cardiovascular risk factors. The study s…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Effect of Increased Daily Water Intake in Patients With Hyperuricemia [NA]
A completed clinical trial evaluating whether increasing daily water intake affects hyperuricemia.
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: PK and Safety Evaluation Study of SAP-001 in Adult Subjects With Normal and Impaired Renal Function [Phase 1, Phase 2]
This clinical trial update describes pharmacokinetic and safety evaluation of SAP-001 in adult subjects with normal and impaired renal funct…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Non-Inferiority Study of Aliskiren vs Losartan in the Treatment of Hypertension With Hyperuricemia [Phase 4]
Phase 4 trial updates completion of a non-inferiority study comparing aliskiren to losartan for hypertension with hyperuricemia.
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: SAD,MAD and Food Effect Study of SAP-001 Tablets in Chinese Subjects [Phase 1]
Phase 1 SAD/MAD and food-effect study of SAP-001 tablets in Chinese subjects has completed. Sponsor: Shanton Pharma Co., Ltd.
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Possible Pharmacological Effect of Quercetin in the Management of Hyperuricemia - Results From Real-life Clinical Studies
This update reports real-life clinical study results suggesting quercetin may have a pharmacological effect in managing hyperuricemia; findi…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: Quercetin as Possible Supportive Therapy for Mild to Moderate Hyperuricemia [NA]
A completed clinical trial evaluated quercetin as a potential supportive therapy for mild to moderate hyperuricemia.
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Evaluate the Efficacy and Safety of D-0120 in Primary Hyperuricemia Patients [Phase 2]
Phase 2 trial of D-0120 in primary hyperuricemia has completed, assessing efficacy and safety.
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: GOS and the Management of Hyperuricemia [NA]
An ongoing Sun Yat-sen University clinical trial is evaluating galacto-oligosaccharides (GOS) for managing hyperuricemia; the study is curre…
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CLINICAL_TRIALS trial_result · 2024-10-03Clinical Trial Update: Vegan Diet, Amla Fruits and Uric Acid [NA]
A completed clinical trial from Fu Jen Catholic University evaluating the effects of a vegan diet and amla fruit on uric acid levels in hype…
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CLINICAL_TRIALS research · 2024-10-02Clinical Trial Update: The Effects of Febuxostat Dose Tapering in Gout Patients Optimally Controlled for 5 Years or More [Phase 4]
Phase 4 clinical trial assessing whether tapering febuxostat dosing is safe and effective in gout patients who have had uric acid control fo…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Phase II/III Study of AR882 Capsules Compared to Febuxostat Tablets in Patients with Primary Gout and Hyperuricemia [Phase 2, Phase 3]
A Phase 2/3 clinical trial is evaluating AR882 capsules versus febuxostat tablets in adults with primary gout and hyperuricemia; the study i…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Screening and Management of Hyperuricemia in Patients with Chronic Medical Diseases in Assiut University Hospital
This clinical trial entry describes screening and management of hyperuricemia in patients with chronic medical diseases at Assiut University…
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FDA approval · 2024-08-30FDA Approved: ALLOPURINOL — Supplemental Application (Camber Pharmaceuticals, Inc.)
FDA approved a supplemental application for Allopurinol from Camber Pharmaceuticals, Inc. under the ANDA program. This action constitutes a …
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EMA approval · 2024-08-12EMA Authorised: Fasturtec (rasburicase) — Sanofi Winthrop Industrie
The EMA authorised Fasturtec (rasburicase) by Sanofi Winthrop Industrie for hyperuricemia.
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CLINICAL_TRIALS trial_result · 2024-08-05Clinical Trial Update: A Safety and Tolerability Study of FCN-207 in Healthy Volunteers [Phase 1]
Phase 1 safety and tolerability study of FCN-207 in healthy volunteers has completed.
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FDA approval · 2024-07-22FDA Approved: FEBUXOSTAT — Supplemental Application (HEC Pharm USA Inc.)
FDA approved a supplemental application for FEBUXOSTAT submitted by HEC Pharm USA Inc. The action supplements the approved Febuxostat produc…
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CLINICAL_TRIALS research · 2024-07-15Clinical Trial Update: CPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive Sleep Apnea [Phase 4]
A Phase 4 clinical trial evaluating whether CPAP therapy affects lipid profiles and hyperuricemia in adults with dyslipidemia and moderate-t…
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Pharmacokinetic/Pharmacokinetic and Safety Studies of SHR4640 in Subjects With Moderate Renal Insufficiency and Healthy Subjects [Phase 1]
Phase 1 pharmacokinetic and safety studies of SHR4640 in subjects with moderate renal impairment and healthy volunteers have been completed.…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Acute Effects of Tart Cherry on Uric Acid and Biomarkers of CVD Risk in Healthy Individuals [NA]
A completed clinical trial evaluating the acute effects of tart cherry on uric acid levels and biomarkers of cardiovascular disease risk in …
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CLINICAL_TRIALS research · 2024-06-05Clinical Trial Update: Prebiotics and the Management of Hyperuricemia [NA]
A Sun Yat-sen University study is evaluating prebiotics to manage hyperuricemia; the trial is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Clinical Trial of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults [Phase 3]
This document reports a Phase 3 clinical trial of HR091506 tablets for gout with hyperuricemia in adults that is not yet recruiting.