Hypertension
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Sign up freeTop drugs studied for this disease
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FDA approval · 2020-02-19FDA Approved: ETHACRYNIC ACID — Original Application (Upsher-Smith Laboratories, LLC)
FDA approved Upsher-Smith's original generic application for Ethacrynic acid, a loop diuretic.
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CLINICAL_TRIALS trial_result · 2020-02-11Clinical Trial Update: A Clinical Study to Evaluate Safety & Efficacy of the Combination of Aliskiren, Valsartan & Hydrochlorothiazide in Diabetic Hypertensive Nonresponder Patients [Phase 3]
Phase 3 trial evaluating the safety and efficacy of the combination of Aliskiren, Valsartan, and Hydrochlorothiazide in diabetic hypertensiv…
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FDA approval · 2020-02-10FDA Approved: LOTREL — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for LOTREL (amlodipine besylate and benazepril hydrochloride) by Novartis Pharmaceuticals Corporatio…
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: Vitamin D, Insulin Resistance, and Cardiovascular Disease [NA]
Clinical trial update for a study on vitamin D, insulin resistance, and cardiovascular disease has completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: Comparative Effects of Perindopril and Zofenopril on Blood Pressure Control and Oxidative Status Blacks Hypertensive Patients. [Phase 4]
Phase 4 trial comparing the effects of perindopril and zofenopril on blood pressure control and oxidative status in Black hypertensive patie…
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CLINICAL_TRIALS research · 2020-02-05Clinical Trial Update: Safety and Feasibility of Remote Ischemic Conditioning on Prehypertension and Early-stage Hypertension [Phase 1, Phase 2]
A Phase 1/2 clinical trial exploring the safety and feasibility of remote ischemic conditioning for individuals with prehypertension and ear…
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: Short Term Cardiovascular Effects and Oxidative Status of Calcium and Vitamin D Supplementation of Postmenopausal Hypertensive Blacks Women [Phase 4]
Phase 4 trial update evaluating short-term cardiovascular effects and oxidative status from calcium and vitamin D supplementation in postmen…
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CLINICAL_TRIALS trial_result · 2020-01-31Clinical Trial Update: The Efficacy of a Combination of Telmisartan/S-Amlodipine Compared With Telmisartan Monotherapy [Phase 4]
Phase 4 trial comparing a telmisartan/S-amlodipine combination with telmisartan alone for hypertension has completed.
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CLINICAL_TRIALS trial_result · 2020-01-30Clinical Trial Update: A Mobile Personal Health Record for Behavioral Health Homes [NA]
Completed clinical trial evaluating a mobile personal health record for behavioral health homes; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-01-21Clinical Trial Update: A Study Examining the Effects of Nebivolol Compared to Atenolol on Endothelial Function [Phase 2]
Phase 2 trial comparing nebivolol to atenolol on endothelial function in hypertension; completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: 307B - Safety, Tolerability and Pharmacokinetics Study of TOPROL-XL® in Hypertensive Pediatric Subjects [Phase 3]
A Phase 3 safety, tolerability, and pharmacokinetics study of TOPROL-XL in hypertensive pediatric subjects has completed.
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CLINICAL_TRIALS trial_result · 2020-01-14Clinical Trial Update: Amlodipine Versus Valsartan for Improvement of Diastolic Dysfunction Associated With Hypertension [Phase 4]
A phase 4 trial comparing amlodipine to valsartan for improvement of diastolic dysfunction associated with hypertension has completed.
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CLINICAL_TRIALS withdrawal · 2020-01-14Clinical Trial Update: Ertugliflozin Versus Hydrochlorothiazide in Reducing Sympathetic Neural Overactivity in Patients With Hypertension and Recently-diagnosed Type 2 Diabetes. [Phase 4]
Phase 4 trial comparing ertugliflozin to hydrochlorothiazide for reducing sympathetic neural overactivity in patients with hypertension and …
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FDA approval · 2020-01-06FDA Approved: PROPRANOLOL HYDROCHLORIDE — Original Application (Lannett Company, Inc.)
FDA approved the original application for propranolol hydrochloride from Lannett Company, Inc., enabling a generic version to be marketed.
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CLINICAL_TRIALS trial_result · 2019-12-23Clinical Trial Update: A Phase 3 Long-term Study of TAK-536 in Pediatric Patients 6 to Less Than 16 Years With Hypertension [Phase 3]
Phase 3 long-term study of TAK-536 in children with hypertension has completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-12-23Clinical Trial Update: Short Term Effect of Empagliflozin in Hypertension [Phase 4]
Phase 4 clinical trial update evaluating the short-term effect of empagliflozin in hypertension has completed.
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FDA approval · 2019-12-20FDA Approved: OLMESARTAN MEDOXOMIL / AMLODIPINE BESYLATE / HYDROCHLOROTHIAZIDE — Supplemental Application (Par Health USA, LLC)
The FDA approved a supplemental application for Par Health USA’s generic fixed-dose combination tablet of olmesartan medoxomil, amlodipine b…
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FDA approval · 2019-12-19FDA Approved: CONJUPRI — Original Application (CSPC Ouyi Pharmaceutical Co. Ltd)
FDA approved CONJUPRI (levamlodipine) through an Original Application by CSPC Ouyi Pharmaceutical Co. Ltd for indications including hyperten…
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FDA approval · 2019-12-18FDA Approved: AMLODIPINE AND ATORVASTATIN — Supplemental Application (Prasco Laboratories)
FDA approved a supplemental application for the amlodipine besylate and atorvastatin calcium combination product, submitted by Prasco Labora…
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women [Phase 2]
Phase 2 trial examining worksite wellness interventions and their effects on vascular function, insulin sensitivity, and HDL in overweight o…
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CLINICAL_TRIALS trial_result · 2019-12-16Clinical Trial Update: Study of Febuxostat Effect on Blood Pressure in Patients With High Normal Blood Pressure [Phase 4]
Phase 4 clinical trial update evaluating the effect of febuxostat on blood pressure in patients with high normal blood pressure and gout; st…
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FDA approval · 2019-12-13FDA Approved: CAPTOPRIL — Original Application (Ajanta Pharma USA Inc.)
This document reports the FDA approval of CAPTOPRIL as a generic product (Original Application) by Ajanta Pharma USA Inc.
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CLINICAL_TRIALS trial_result · 2019-12-12Clinical Trial Update: The Effect of Nebivolol on Insulin Sensitivity [NA]
A completed clinical trial evaluating the effect of nebivolol on insulin sensitivity in hypertension patients, with results posted in 2019.
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FDA approval · 2019-12-10FDA Approved: OLMESARTAN MEDOXOMIL, AMLODIPINE AND HYDROCHLOROTHIAZIDE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for a fixed-dose combination of olmesartan medoxomil, amlodipine, and hydrochlorothiazide manufactur…
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CLINICAL_TRIALS trial_result · 2019-12-09Clinical Trial Update: Efficacy of Chlorthalidone and Hydrochlorothiazide Combined With Amiloride on Blood Pressure in Primary Hypertension. [Phase 3]
Phase 3 trial update assessing the combination of chlorthalidone and hydrochlorothiazide with amiloride for blood pressure control in primar…