Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2008-07-24Clinical Trial Update: Atrial Fibrillation Incidence, Risk Factors and Genetics
This clinical trial update highlights the incidence of atrial fibrillation, its risk factors, and genetic associations identified in the stu…
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FDA approval · 2008-07-23FDA Approved: EXFORGE — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for EXFORGE (amlodipine besylate and valsartan) from Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2008-07-22Clinical Trial Update: Canadian Study of Trandolapril on Blood Pressure in Hypertensive Patients (TRAIL) [Phase 4]
A Phase 4 Canadian trial evaluating the blood pressure effects of trandolapril in hypertensive patients (TRAIL) has completed.
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FDA approval · 2008-07-17FDA Approved: DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE — Supplemental Application (Endo USA, Inc.)
FDA approved a supplemental application for Diltiazem Hydrochloride Extended-Release from Endo USA, Inc., resulting in an approved update to…
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CLINICAL_TRIALS trial_result · 2008-07-16Clinical Trial Update: Family Blood Pressure Program - GENOA (Genetic Epidemiology Network of Atherosclerosis)
The GENOA trial investigating the genetic epidemiology of atherosclerosis and hypertension has been terminated.
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CLINICAL_TRIALS trial_result · 2008-07-15Clinical Trial Update: Tarka® vs. Lotrel® in Hypertensive, Diabetic Subjects With Renal Disease (TANDEM) [Phase 4]
A Phase 4 trial (TANDEM) comparing Tarka (trandolapril/verapamil) with Lotrel (amlodipine/benazepril) in hypertensive, diabetic patients wit…
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CLINICAL_TRIALS trial_result · 2008-07-15Clinical Trial Update: A Study for Prevention of Kidney Disease in Diabetic Patients (BENEDICT) [Phase 4]
This update reports the completion of the Phase 4 BENEDICT trial evaluating prevention of kidney disease in diabetic patients. The study inc…
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CLINICAL_TRIALS trial_result · 2008-07-15Clinical Trial Update: Tarka vs. Hyzaar in Patients With Metabolic Syndrome (STAR) [Phase 4]
Phase 4 trial comparing Tarka (trandolapril/verapamil) with Hyzaar (losartan/hydrochlorothiazide) in patients with hypertension and metaboli…
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CLINICAL_TRIALS trial_result · 2008-07-10Clinical Trial Update: Russian Study of the Efficacy and Safety of Tarka in Patients With Hypertension [Phase 4]
A Phase 4 trial conducted in Russia evaluated the efficacy and safety of Tarka (trandolapril/verapamil) in patients with hypertension; the s…
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CLINICAL_TRIALS trial_result · 2008-07-10Clinical Trial Update: Pharmacy Implementation Trial: Adherence to Antihypertensive Therapy [NA]
The Pharmacy Implementation Trial on adherence to antihypertensive therapy has completed.
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CLINICAL_TRIALS trial_result · 2008-07-04Clinical Trial Update: The Effect of Calcium Supplementation on Insulin Resistance and 24h Blood Pressure [Phase 4]
Phase 4 clinical trial evaluating whether calcium supplementation affects insulin resistance and 24-hour blood pressure. The study is comple…
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CLINICAL_TRIALS trial_result · 2008-07-04Clinical Trial Update: Correlation of Flicker Induced and Flow Mediated Vasodilatation in Patients With Endothelial Dysfunction and Healthy Volunteers. [NA]
The completed trial assessed the correlation between flicker-induced vasodilatation and flow-mediated vasodilatation in patients with endoth…
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CLINICAL_TRIALS trial_result · 2008-06-25Clinical Trial Update: The Relaxation and Blood Pressure in Pregnancy (REBIP) Study [NA]
The REBIP trial, investigating relaxation and blood pressure in pregnancy for women with hypertension-related conditions, has completed. The…
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FDA approval · 2008-06-20FDA Approved: RAMIPRIL — Original Application (GSMS, Incorporated)
FDA approved RAMIPRIL as a generic drug under an original Abbreviated New Drug Application (ANDA 079116) filed by GSMS, Incorporated.
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CLINICAL_TRIALS research · 2008-06-19Clinical Trial Update: Survey of Thai-Muslim Health Status
This document reports the completion of a Mahidol University survey studying health status among Thai-Muslim populations, focusing on diabet…
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CLINICAL_TRIALS trial_result · 2008-06-18Clinical Trial Update: Efficacy and Safety of Valsartan, Hydrochlorothiazide and Amlodipine Combination Therapy in Hypertension [Phase 4]
Phase 4 clinical trial update reporting on the efficacy and safety of a triple combination therapy (valsartan, hydrochlorothiazide, and amlo…
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FDA approval · 2008-06-18FDA Approved: RAMIPRIL — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved Hikma Pharmaceuticals USA Inc.'s original ANDA for ramipril, authorizing the marketing of a generic ramipril product.
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FDA approval · 2008-06-18FDA Approved: RAMIPRIL — Original Application (Chartwell RX, LLC.)
The FDA approved Chartwell RX, LLC's original generic application for ramipril, enabling the marketing of a RAMIPRIL product.
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CLINICAL_TRIALS trial_result · 2008-06-17Clinical Trial Update: Efficacy of the New Closure Device in Improving Patient Compliance in Treatment of Hypertension With Valsartan+/-Hydrochlorothiazide (HCTZ) at 6 Months [Phase 4]
Phase 4 clinical trial update assessing a closure device to improve adherence in hypertension treatment with valsartan, with or without hydr…
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CLINICAL_TRIALS trial_result · 2008-06-10Clinical Trial Update: Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin. [Phase 4]
Phase 4 clinical trial evaluating whether simvastatin and atorvastatin reduce oxidative stress in patients with diabetes mellitus and hypert…
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CLINICAL_TRIALS trial_result · 2008-06-05Clinical Trial Update: Autoregulation of Glomerular Filtration Rate in Patients With Type 1 Diabetes During Spironolactone Therapy [Phase 4]
Phase 4 study examining how spironolactone affects autoregulation of the glomerular filtration rate in patients with Type 1 diabetes and hyp…
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FDA label_change · 2008-05-29FDA Approved: LOTENSIN — Supplemental Application (Validus Pharmaceuticals LLC)
FDA Supplemental Application for Lotensin (benazepril hydrochloride) submitted by Validus Pharmaceuticals LLC.
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FDA approval · 2008-05-29FDA Approved: BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE — Supplemental Application (Padagis US LLC)
FDA approved a supplemental application for Benazepril hydrochloride and hydrochlorothiazide, indicating approved changes to the product's l…
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FDA approval · 2008-05-29FDA Approved: AMLODIPINE AND ATORVASTATIN — Supplemental Application (Prasco Laboratories)
FDA approved a supplemental application for a fixed-dose combination of amlodipine besylate and atorvastatin calcium (amlodipine and atorvas…
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CLINICAL_TRIALS trial_result · 2008-05-29Clinical Trial Update: LACTOPRES:Study on the Effect of Dairy Peptides on Blood Pressure in Untreated Hypertensive Subjects. [Phase 2]
Phase 2 trial investigating the effect of dairy-derived lactotripeptides on blood pressure in untreated hypertensive adults; the study has c…