Hyperkalemia
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: An Observational Prospective Cohort Study for Long-term Management of Hyperkalemia in Patients With Chronic Kidney Disease or Heart Failure
This document reports an update on an observational prospective cohort study evaluating long-term management of hyperkalemia in patients wit…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Tracking Treatment Pathways in Adult Patients With Hyperkalemia.
This document reports that a sponsor-led clinical trial investigating treatment pathways for hyperkalemia in adults has completed.
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Prevalence and Risk Factors of Hyperkalemia in Non-Dialysis Chronic Kidney Disease Patients in Community
This clinical trial investigates the prevalence and risk factors of hyperkalemia among non-dialysis chronic kidney disease patients in commu…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone [Phase 4]
Phase 4 study update shows completion and posted results for the efficacy and safety of Sodium Zirconium Cyclosilicate (SZC) in managing hyp…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosilicate in Heart Failure [Phase 2]
Phase 2 clinical trial update on optimizing aldosterone receptor antagonist therapy using Sodium Zirconium Cyclosilicate in heart failure. T…
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CLINICAL_TRIALS trial_result · 2025-06-18Clinical Trial Update: Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes) [Phase 3]
Phase 3 trial evaluating the effect of sodium zirconium cyclosilicate on arrhythmia-related cardiovascular outcomes in adults on chronic hem…
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FDA approval · 2025-06-10FDA Approved: SODIUM POLYSTYRENE SULFONATE — Original Application (Burel Pharmaceuticals, LLC)
FDA approved the original application for sodium polystyrene sulfonate, a generic version by Burel Pharmaceuticals, LLC, for the management …
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: The ORTIZ Study: Optimising RASi Therapy With SZC [Phase 2]
Phase 2 ORTIZ trial evaluating sodium zirconium cyclosilicate (SZC) to optimize renin-angiotensin system inhibitor therapy in CKD and type 2…
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: VITALIZE.Use and Effectiveness of Sodium Zirconium Cyclosilicate (LokelmaTM) in the Real-world Setting in Spain
Completed real-world study evaluating the use and effectiveness of Lokelma (sodium zirconium cyclosilicate) for hyperkalemia in Spain.
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients [Phase 4]
Phase 4 trial evaluating whether patiromer reduces episodic hyperkalemia in patients with end-stage renal disease. Results were posted on 20…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia. [Phase 3]
Phase 3 study evaluating the safety and efficacy of ZS for hyperkalemia has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Effect of Viscous Fiber on Postprandial Kalemic Response in Hemodialysis Patients
A clinical trial evaluating whether viscous fiber affects postprandial potassium levels in patients on hemodialysis has completed.
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4 [Phase 4]
Phase 4 clinical trial update evaluating whether Sodium Zirconium Cyclosilicate enables liberal fruit and vegetable intake for patients with…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients [NA]
A completed clinical trial comparing sodium zirconium cyclosilicate (SZC) with sodium polystyrene sulfonate (SPS) for treatment of hyperkale…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: the Cardioprotective Effects of Improving Potassium Variability in Maintenance Hemodialysis Patients [Phase 4]
Phase 4 clinical trial update evaluating whether improving potassium variability provides cardioprotection in patients undergoing maintenanc…
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: Lower Vs. Standard Insulin-Dextrose Doses for Treating Mild to Moderate Hyperkalemia in the Emergency Department [NA]
This clinical trial compares lower versus standard insulin-dextrose doses for treating mild to moderate hyperkalemia in the emergency depart…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: A Multicenter, Prospective, Non-interventional Cohort Study to Evaluate the Safety and Treatment Pattern of Sodium Zirconium Cyclosilicate for Hyperkalaemia Management in Real World Practice in China
Completed multicenter prospective non-interventional cohort study in China assessing the safety and real-world treatment patterns of sodium …
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: Safety of Oral Resin for Treatment of Hyperkalemia in Chinese Patients With Renal Insufficiency
A completed clinical trial evaluates the safety of an investigational oral resin for treating hyperkalemia in Chinese patients with renal in…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Patiromer Trial in CKD Stage IIIB to V [Phase 3]
A Phase 3 trial of patiromer in chronic kidney disease patients with hyperkalemia was terminated.
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: Cardiovascular and Renal Treatment in Heart Failure Patients With Hyperkalaemia or at High Risk of Hyperkalaemia
A clinical trial update indicating that the study evaluating cardiovascular and renal treatment in heart failure patients with hyperkalemia …
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CLINICAL_TRIALS research · 2024-10-10Clinical Trial Update: Chronic Kidney Disease, Hyperkalemia and Echocardiographic Changes
A clinical trial is currently recruiting to study echocardiographic changes in patients with chronic kidney disease and hyperkalemia, includ…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Artificial Intelligence Identified Dyskalemia Using Electrocardiogram (AIDE) [NA]
The AIDE study completed, evaluating an AI approach to identify dyskalemia from electrocardiograms in patients with hyperkalemia or hypokale…
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EMA approval · 2024-06-11EMA Authorised: Veltassa (patiromer sorbitex calcium) — Vifor Fresenius Medical Care Renal Pharma France
The European Medicines Agency authorised Veltassa (patiromer sorbitex calcium) for the treatment of hyperkalemia; the marketing authorizatio…
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CLINICAL_TRIALS trial_result · 2024-06-05Clinical Trial Update: A Prospective, Randomized, Open-Label, Cross-Over Study of Lokelma to Control Interdialytic Hyperkalemia [Phase 4]
Phase 4 randomized, open-label, cross-over study evaluating Lokelma for control of interdialytic hyperkalemia.
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FDA approval · 2024-05-03FDA Approved: KIONEX — Supplemental Application (ANI Pharmaceuticals, Inc.)
The FDA approved a supplemental application for KIONEX (sodium polystyrene sulfonate) submitted by ANI Pharmaceuticals, Inc.