Hypercholesterolemia
📧 Sign up to get email alerts when something new happens for Hypercholesterolemia.
Sign up freeTop drugs studied for this disease
-
FDA approval · 2017-03-27FDA Approved: ATORVASTATIN CALCIUM — Original Application (Teva Pharmaceuticals USA, Inc.)
FDA approves Teva's atorvastatin calcium as an original-application generic product.
-
CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Study to Evaluate the Efficacy and Safety of an Every Four Weeks Treatment Regimen of Alirocumab (REGN727/ SAR236553) in Patients With Primary Hypercholesterolemia (ODYSSEY CHOICE 1) [Phase 3]
Phase 3 study ODYSSEY CHOICE 1 evaluated the efficacy and safety of an every-four-weeks dosing regimen of alirocumab (Praluent) in patients …
-
FDA approval · 2017-03-21FDA Approved: ROSUVASTATIN CALCIUM — Original Application (Ascend Laboratories, LLC)
FDA approves the original ANDA for rosuvastatin calcium from Ascend Laboratories, LLC, enabling the generic rosuvastatin calcium product to …
-
CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: The Effects of Lowering Low-density Lipoprotein Cholesterol Levels to New Targets on Cardiovascular Complications in Peritoneal Dialysis Patients [NA]
Clinical trial evaluating whether lowering LDL cholesterol to new targets reduces cardiovascular complications in peritoneal dialysis patien…
-
CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: Phase III Study To Evaluate Alirocumab in Patients With Hypercholesterolemia Not Treated With a Statin (ODYSSEY CHOICE II) [Phase 3]
Phase III ODYSSEY CHOICE II evaluated alirocumab in patients with hypercholesterolemia not treated with a statin; results were posted in Mar…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2017-03-01Clinical Trial Update: Metabolic Abnormalities in HIV Infected and Uninfected Young Women
A completed clinical trial update examining metabolic abnormalities in HIV-infected and uninfected young women.
-
CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: Effect of Red Yeast Rice, Phytosterols and L-tyrosol on Lipid Profile and Endothelial Function [NA]
A completed clinical trial evaluated the effects of red yeast rice, phytosterols, and L-tyrosol on lipid profile and endothelial function in…
-
CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: A 10-12 Week Study to Evaluate the Safety and Efficacy of 320 mg Valsartan and 80 mg Simvastatin in Combination and as Monotherapies in Treating Hypertension and Hypercholesterolemia [Phase 3]
A completed Phase 3 trial evaluating a fixed combination of valsartan 320 mg and simvastatin 80 mg versus monotherapies for hypertension and…
-
CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Efficacy and Safety of Fluvastatin in Different Doses in Adults With Mixed Dyslipidemia or Primary Hypercholesterolemia [Phase 3]
This entry notes the completion of a Phase 3 trial evaluating different doses of fluvastatin for efficacy and safety in adults with mixed dy…
-
CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: Effect of an Investigational Compound on Tolerability of Extended Release Niacin (0524A-023)(COMPLETED) [Phase 3]
Phase 3 trial update showing completion of a study evaluating an investigational compound's effect on the tolerability of extended-release n…
-
CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: Tolerability of MK0524A Versus Niacin Extended-Release (0524A-054) [Phase 3]
Phase 3 trial comparing tolerability of MK0524A to niacin extended-release in patients with high cholesterol has completed.
-
FDA approval · 2017-02-03FDA Approved: PITAVASTATIN — Original Application (Upsher-Smith Laboratories, LLC)
The FDA approved an original ANDA for pitavastatin calcium from Upsher-Smith Laboratories, making a generic pitavastatin product available.
-
CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: The Effects of a Spread With Added Plant Sterols and Omega-3 Fatty Acids on Blood Lipids [NA]
A completed clinical trial sponsored by Unilever R&D evaluated the effects of a spread enriched with plant sterols and omega-3 fatty acids o…
-
CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: The Effect of Plant Sterols on the Blood Lipid Profile of Subjects With and at High Risk of Type 2 Diabetes Mellitus [NA]
A completed clinical trial sponsored by Unilever R&D evaluated the effect of plant sterols on blood lipid profiles in adults with Type 2 dia…
-
CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: The Effects of Metformin on Blood Vessel Structure and Function [Phase 2]
Phase 2 trial results evaluating metformin's effects on blood vessel structure and function in individuals with obesity and related metaboli…
-
CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: A Study Comparing CoQ10 Levels While Taking 3 Different Statins [Phase 4]
A Phase 4 clinical trial evaluating CoQ10 levels in patients taking three different statins for hypercholesterolemia has completed, with res…
-
CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Measuring the Impact of Dietary Supplementation With a New Baking Product on Gut Microbiota and Cholesterol Metabolism [NA]
Completed clinical trial evaluating a dietary baking product's effects on gut microbiota and cholesterol metabolism in individuals with hype…
-
CLINICAL_TRIALS trial_result · 2016-12-26Clinical Trial Update: Phase III Clinical Trial to Evaluate the Efficacy and Safety of DP-R208 and Each Monotherapy [Phase 3]
Phase III trial evaluating DP-R208 and each monotherapy for hypertension and hypercholesterolemia has completed.
-
CLINICAL_TRIALS trial_result · 2016-12-13Clinical Trial Update: A Study to Evaluate Efficacy and Safety of Extended-Release Niacin + Laropiprant + Simvastatin in Participants With Primary Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-118) [Phase 3]
Phase 3 trial evaluating extended-release niacin combined with laropiprant and simvastatin in primary hypercholesterolemia or mixed dyslipid…
-
CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Pilot Study in the Cholesterol Absorption Reduction After Consumption of Low-fat, Drinkable Fermented Milk Enriched With Plant Sterols [NA]
This record reports a completed pilot trial evaluating the effect of a low-fat, drinkable fermented milk enriched with plant sterols on chol…
-
CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (France) [NA]
A completed clinical trial evaluating the effects of consuming fermented milk enriched with plant sterols in mildly hypercholesterolemic adu…
-
CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (Spain) [NA]
Update on a completed clinical trial in Spain evaluating whether consuming a fermented milk product enriched with plant sterols lowers hyper…
-
CLINICAL_TRIALS trial_result · 2016-11-25Clinical Trial Update: Effects of Fermented Milk Product Enriched With Plant Sterols and Policosanols in Mild Hypercholesterolaemic Adults [NA]
This clinical trial update reports the completion of a study evaluating a fermented milk product enriched with plant sterols and policosanol…
-
CLINICAL_TRIALS trial_result · 2016-11-25Clinical Trial Update: Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (Italy) [NA]
This completed clinical trial evaluated the effect of consuming a plant sterol–enriched fermented milk on cholesterol levels in mildly hyper…
-
CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Guideline Adherence for Heart Health [Phase 2]
Phase 2 trial update evaluating adherence to guidelines for heart health in people with cardiovascular diseases and related risk factors.