Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-05-26Clinical Trial Update: Evolocumab Plus Ezetimibe in High Risk Haemodialized Statin Intolerant Patients [Phase 4]
Phase 4 clinical trial evaluating evolocumab plus ezetimibe in high-risk statin-intolerant patients undergoing hemodialysis.
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FDA approval · 2020-05-21FDA Approved: CRESTOR — Supplemental Application (AstraZeneca Pharmaceuticals LP)
The FDA approved a Supplemental Application for CRESTOR (rosuvastatin) submitted by AstraZeneca Pharmaceuticals LP, updating the drug's labe…
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CLINICAL_TRIALS trial_result · 2020-04-27Clinical Trial Update: Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk [Phase 3]
Phase 3 trial update assessing long-term efficacy of bempedoic acid in patients with hypercholesterolemia at high cardiovascular risk; resul…
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: Investigating the Effects of Lipid-therapy Intensification With Alirocumab on Endothelial Function, Carotid Arteries, Lipoprotein Particle Subfractions, Inflammation and Post-prandial Lipemia [Phase 4]
Phase 4 trial investigating alirocumab intensification effects on endothelial function, carotid arteries, lipoprotein subfractions, inflamma…
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CLINICAL_TRIALS trial_result · 2020-04-20Clinical Trial Update: Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony) [Phase 3]
Phase 3 long-term safety and tolerability evaluation of ETC-1002 in high-risk hyperlipidemia patients completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-04-14Clinical Trial Update: Effect of an Atlantic Diet on Anthropometric Indices and Serum Lipid Profile [NA]
A completed clinical trial evaluating the effects of an Atlantic diet on anthropometric measures and lipid profile in individuals with cardi…
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-C [Phase 2]
Phase 2 trial evaluating a fixed-dose combination of bempedoic acid and ezetimibe in patients with type 2 diabetes and elevated LDL-C has co…
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated Triglycerides [Phase 2]
Phase 2 trial update assessing efficacy and safety of gemcabene in patients with low HDL-C and varying triglyceride levels; study completed.
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients on Stable Statin Therapy [Phase 2]
Phase 2 trial update reporting efficacy and safety of gemcabene in hypercholesterolemia patients on stable statin therapy.
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients as Monotherapy or in Combination With Atorvastatin [Phase 2]
Phase 2 trial update on gemcabene for hypercholesterolemia assessing monotherapy or combination with atorvastatin; completed.
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FDA approval · 2020-04-07FDA Approved: ROSUVASTATIN CALCIUM — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approves Sun Pharmaceutical's supplemental application for ROSUVASTATIN CALCIUM, a generic rosuvastatin calcium product, under approved …
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility) [Phase 3]
Phase 3 trial update assessing bempedoic acid added to ezetimibe for lowering LDL-C in patients with hypercholesterolemia/atherosclerosis.
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin Intolerant [Phase 3]
Phase 3 trial evaluating the efficacy and safety of bempedoic acid (ETC-1002) in hyperlipidemia patients intolerant to statins; study comple…
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-C [Phase 2]
Phase 2 trial evaluating a triplet therapy (bempedoic acid, ezetimibe, atorvastatin) for elevated LDL-C; results posted after completion.
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg When Added to PCSK9 Inhibitor Therapy [Phase 2]
Phase 2 trial evaluating the added efficacy and safety of bempedoic acid (ETC-1002) 180 mg in combination with PCSK9 inhibitor therapy for h…
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CLINICAL_TRIALS trial_result · 2020-03-30Clinical Trial Update: Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE) [Phase 3]
Phase 3 trial update on alirocumab (ODYSSEY APPRISE) evaluating safety, tolerability, and effect in high cardiovascular risk patients with s…
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CLINICAL_TRIALS trial_result · 2020-03-13Clinical Trial Update: Effect of Atorvastatin on Carotid Intima Media Thickness [Phase 4]
Phase 4 trial update on atorvastatin and its effect on carotid intima-media thickness in patients with essential hypertension and hyperchole…
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FDA approval · 2020-03-09FDA Approved: ROSUVASTATIN CALCIUM — Supplemental Application (Glenmark Pharmaceutials Inc., USA)
FDA approved Glenmark's supplemental application for rosuvastatin calcium, authorizing a generic rosuvastatin calcium product and expanding …
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FDA approval · 2020-03-09FDA Approved: ROSUVASTATIN CALCIUM — Supplemental Application (Westminster Pharmaceuticals, LLC)
FDA approves Westminster Pharmaceuticals' supplemental application for rosuvastatin calcium, confirming this rosuvastatin salt as an approve…
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FDA approval · 2020-03-09FDA Approved: ROSUVASTATIN CALCIUM — Supplemental Application (Rising Pharma Holdings, Inc.)
The FDA approved a supplemental application for Rosuvastatin Calcium from Rising Pharma Holdings, Inc., enabling this rosuvastatin calcium g…
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FDA approval · 2020-02-21FDA Approved: NEXLETOL — Original Application (Esperion Therapeutics, Inc.)
FDA approved Nexletol (bempedoic acid) as an original application for adults with heterozygous familial hypercholesterolemia or established …
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FDA approval · 2020-02-21FDA Approved: ROSUVASTATIN CALCIUM — Supplemental Application (Quallent Pharmaceuticals Health LLC)
FDA approved a supplemental application for Rosuvastatin Calcium from Quallent Pharmaceuticals Health LLC, establishing a generic rosuvastat…
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CLINICAL_TRIALS trial_result · 2020-02-12Clinical Trial Update: Alirocumab in Patients on a Stable Dialysis Regimen [Phase 3]
Phase 3 clinical trial evaluating alirocumab in patients on stable dialysis regimens to assess lipid-lowering efficacy and safety.
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FDA approval · 2020-01-29FDA Approved: EZETIMIBE AND SIMVASTATIN — Supplemental Application (Ascend Laboratories, LLC)
The FDA approved a supplemental application for the ezetimibe and simvastatin combination product from Ascend Laboratories LLC.
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Efficacy/Safety of Rosuvastatin+Ezetimibe in High Risk Patients With Primary Hypercholesterolemia/Mixed Dyslipidemia [Phase 3]
Phase 3 trial evaluating rosuvastatin plus ezetimibe in high-risk patients with primary hypercholesterolemia or mixed dyslipidemia has compl…