Human Immunodeficiency Virus Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Generic VEL/SOF With or Without RBV for HIV/HCV Coinfected Patients [Phase 4]
Phase 4 trial evaluating generic Velpatasvir/sofosbuvir with or without ribavirin in HIV/HCV coinfected patients; the study status is comple…
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: Immunogenicity of Fluzone High Dose in Immunocompromised Children and Young Adults [Phase 2]
Phase 2 trial assessing immunogenicity of Fluzone High Dose in immunocompromised pediatric and young adult populations.
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Monoclonal Antibody-based Multipurpose Microbicides
This clinical trial update reports results from a monoclonal antibody–based multipurpose microbicide trial for HIV/STI prevention; the study…
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CLINICAL_TRIALS research · 2017-10-27Clinical Trial Update: German Centre for Infection Research HIV Translational Platform
A clinical trial in Germany focusing on an HIV translational platform is currently recruiting, sponsored by the University Hospital of Colog…
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: SSAT063- Pharmacokinetics of Efavirenz 400 mg Once Daily During Pregnancy in HIV-1 Infected Women [Phase 1]
Phase 1 pharmacokinetic study evaluating efavirenz 400 mg once daily in HIV-1 infected pregnant women. The trial has completed.
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CLINICAL_TRIALS trial_result · 2017-10-16Clinical Trial Update: Shedding, Immunogenicity and Safety of Quadrivalent Live Intranasal Influenza Vaccine (QLAIV) in HIV-infected Children and Young Adults [Phase 2]
Phase 2 trial updates on shedding, immunogenicity, and safety of Quadrivalent Live Intranasal Influenza Vaccine (QLAIV) in HIV-infected chil…
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CLINICAL_TRIALS trial_result · 2017-10-12Clinical Trial Update: Dose-finding Study of GSK2248761 in Antiretroviral Therapy-experienced Subjects With NNRTI-resistant HIV Infection [Phase 2]
Phase 2 dose-finding trial of GSK2248761 in ART-experienced NNRTI-resistant HIV infection; the study was terminated and results were posted.
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FDA approval · 2017-09-25FDA Approved: EPIVIR — Supplemental Application (ViiV Healthcare Company)
The FDA approved a supplemental application for Epivir (lamivudine) submitted by ViiV Healthcare Company.
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CLINICAL_TRIALS trial_result · 2017-09-05Clinical Trial Update: Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery [Phase 2]
A Phase 2 trial evaluated isotretinoin for its effect on immune activation in HIV-1–infected individuals with incomplete CD4+ T cell recover…
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Safety and Efficacy of Allogenic Adoptive Immune Therapy for Advanced AIDS Patients [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and preliminary efficacy of an allogeneic adoptive immune therapy in advanced AIDS patients; the study is r…
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CLINICAL_TRIALS trial_result · 2017-08-25Clinical Trial Update: Promoting Antiretroviral Therapy Among Serodiscordant Couples to Reduce HIV Transmission [NA]
Completed Chinese clinical trial evaluating the use of antiretroviral therapy to reduce HIV transmission in serodiscordant couples. The stud…
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CLINICAL_TRIALS trial_result · 2017-08-15Clinical Trial Update: Addressing Gender Based Violence in HIV Testing and Counseling [NA]
A completed clinical trial update evaluating integration of gender-based violence considerations into HIV testing and counseling programs.
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CLINICAL_TRIALS trial_result · 2017-08-09Clinical Trial Update: A Study to Assess the Drug-drug Interaction of BMS 663068 With Methadone and Also With Buprenorphine/Naloxone [Phase 1]
Phase 1 study completed evaluating potential drug-drug interactions between fostemsavir (BMS-663068) and methadone, and between fostemsavir …
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CLINICAL_TRIALS trial_result · 2017-07-27Clinical Trial Update: Study to Evaluate the Effect of Food on the Pharmacokinetics of BMS-626529 [Phase 1]
A Phase 1 study evaluating the effect of food on the pharmacokinetics of BMS-626529 in HIV infection has completed.
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: Early Infant Diagnosis Point of Care Pilot [NA]
A completed pilot study of early infant diagnosis using point-of-care testing for HIV in Mozambique.
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: Changes in Liver Steatosis After Switching to Raltegravir in HIV/HCV Coinfection [Phase 4]
Phase 4 trial update assessing changes in liver steatosis after switching HIV/HCV coinfected patients to raltegravir; study completed.
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Absolute Bioavailability of BMS-626529 After Oral and Intravenous Dosing [Phase 1]
Phase 1 pharmacokinetic study assessing the absolute bioavailability of BMS-626529 after oral and intravenous dosing.
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CLINICAL_TRIALS research · 2017-07-19Clinical Trial Update: A Clinical Trial of SystemCHANGE to Improve Exercise, Diet and Health in HIV-Infected Adults [NA]
This entry notes the completion of a trial evaluating SystemCHANGE to improve exercise, diet, and health in HIV-infected adults. The study a…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Atripla to Stribild Switch Study to Evaluate Sleep Disturbances [Phase 4]
This Phase 4 switch study evaluated sleep disturbances when moving from Atripla to Stribild in people with HIV/AIDS, with results posted.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Pilot Study of Oral Probiotic Bacteria Supplementation to Reduce Chronic Immune Activation in HIV-infected Malian Women [NA]
A completed pilot clinical trial evaluated whether oral probiotic bacteria supplementation could reduce chronic immune activation in HIV-inf…
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CLINICAL_TRIALS withdrawal · 2017-06-14Clinical Trial Update: A Pilot Study to Determine if Raltegravir Eradicates HIV From Peripheral Blood Mononuclear Cells [Phase 4]
A Phase 4 pilot trial evaluating whether raltegravir can eradicate HIV from peripheral blood mononuclear cells has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-06-09Clinical Trial Update: GSK1349572 Relative Bioavailability Study [Phase 1]
Phase 1 relative bioavailability study of GSK1349572 (dolutegravir) completed to characterize pharmacokinetics and bioavailability.
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CLINICAL_TRIALS research · 2017-06-09Clinical Trial Update: Polypharmacy and Clinically Significant Drug Interactions Among HIV-Infected Patients Receiving Antiretroviral Therapy
A clinical trial update examining polypharmacy and clinically significant drug interactions among HIV-infected patients receiving antiretrov…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Phase 1, Open Label, Two Arm, Fixed Sequence Study to Evaluate the Effect of Rifampin and Rifabutin on GSK1349572 Pharmacokinetics in Healthy Male and Female Volunteers [Phase 1]
Phase 1 open-label study in healthy volunteers to evaluate the effect of rifampin and rifabutin on the pharmacokinetics of GSK1349572 (dolut…
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Immunomodulating Therapy and Improved Vaccination Responses by Cox-2 Inhibitor in HIV-infected Patients [Phase 2]
Phase 2 trial evaluating an immunomodulatory therapy using a COX-2 inhibitor in HIV-infected patients. The study aims to improve vaccination…