Human Immunodeficiency Virus Infection
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: Dysbiosis Impact on Lung Disease in HIV
A completed clinical trial assessed the impact of dysbiosis on lung disease in people with HIV, including those with COPD.
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Safety and Acceptability Study of Non-occupational Prophylaxis (PEP) Following Potential Exposure to HIV [Phase 4]
A Phase 4 safety and acceptability study of non-occupational post-exposure prophylaxis for HIV was terminated, with results posted on 2025-0…
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4011499 in Healthy Participants [Phase 1]
A first-in-human Phase 1 study of VH4011499 in healthy participants assessed safety, tolerability, and pharmacokinetics; the trial is comple…
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: Development of a Multilevel HIV Prevention Intervention for the Emergency Department [NA]
This clinical trial update describes a Brigham and Women's Hospital study to develop a multilevel HIV prevention intervention for the emerge…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: A Study of MGD020 Alone or Combined With MGD014 in Persons With HIV-1 on Antiretroviral Therapy [Phase 1]
A Phase 1 study evaluated MGD020 alone or with MGD014 in people with HIV-1 infection on antiretroviral therapy. Results were posted on 2025-…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Prevention and Treatment Continuum for Youth at HIV Risk, Acutely Infected and With Established HIV Infection
Clinical trial update from UCLA describes a prevention and treatment continuum for youth at risk of HIV, acutely infected, and with establis…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: HIV-1 & Coronavirus-Coinfection in Europe: Morbidity & Risk Factors of COVID-19 in People Living With HIV
This completed observational trial in Europe studied morbidity and risk factors for COVID-19 among people living with HIV-1 infection; resul…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Integrated PrEP Interventions for People Who Inject Drugs in Rural Kentucky [NA]
This ClinicalTrials.gov study evaluated integrated PrEP interventions to prevent HIV among people who inject drugs in rural Kentucky. The tr…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Improving Cervical Cancer Screening in Women Living With HIV Attending Chronic Disease Clinics in Semi-rural Tanzania
A completed clinical trial in semi-rural Tanzania evaluated strategies to improve cervical cancer screening among women living with HIV. The…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Lamivudine/Dolutegravir in Virologically Suppressed Subjects With Expected or Confirmed Resistance to Lamivudine [Phase 2]
Phase 2 trial update of lamivudine/dolutegravir in virologically suppressed HIV patients with lamivudine resistance; the study has completed…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Real-Life Outcomes of TAF/FTC/BIC in HIV Patients in Colombia
A completed real-world study from Colombia evaluating the HIV regimen TAF/FTC/BIC in patients receiving routine care, reporting treatment ou…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: EPIC-P Intervention [NA]
The EPIC-P Intervention trial for HIV has completed, per the registry update. No results are described in this update.
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: Safety and Immunogenicity of HIV DNA-C CN54ENV and Recombinant HIV CN54gp140 Vaccines in Healthy Volunteers [Phase 1]
Phase 1 trial evaluating safety and immunogenicity of HIV DNA-C CN54ENV and CN54gp140 vaccines in healthy volunteers; results have been post…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: COVID-19 Serology in People Living with HIV in Hong Kong
A completed clinical trial evaluating serology for COVID-19 in people living with HIV in Hong Kong.
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: A Drug-Drug Interaction Study of MK 8527 With a Combined Oral Contraceptive (LNG/EE) [Phase 1]
Phase 1 drug-drug interaction study completed evaluating MK-8527 with a combined oral contraceptive (levonorgestrel/ethinyl estradiol) in th…
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: A Single Dose of Pembrolizumab in HIV-Infected People [Phase 1]
This clinical trial update describes a Phase 1 study of a single dose of pembrolizumab in people living with HIV infection. The trial was te…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: First in Human Study of TLC-ART 101 (ACTU 2001) [Phase 1]
This Clinical Trials update documents the first-in-human Phase 1 study of TLC-ART 101 for HIV treatment, with the trial completed under the …
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: Data-informed Stepped Care (DiSC) to Improve Adolescent HIV Outcomes (UH3) [NA]
Clinical trial update for the Data-informed Stepped Care (DiSC) program aimed at improving HIV outcomes in adolescents; the study status is …
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care in Kisarawe, Tanzania [NA]
Completed clinical trial evaluating whether integrated HIV and non-communicable disease screening increases HIV testing uptake and engagemen…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: A Study to Determine the Safety and Efficacy of Rilpivirine in Treatment-naive Indian Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Infection [Phase 3]
Phase 3 study evaluating the safety and efficacy of rilpivirine in treatment-naive HIV-1 infection patients in India has been terminated.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Biomarkers for Event-driven PrEP Adherence [Phase 4]
Phase 4 clinical trial update reporting results on biomarkers to monitor adherence to event-driven HIV pre-exposure prophylaxis.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Integrase Regimen Switch to Symtuza to Increase Tolerability/Adherence (SYMita) [Phase 4]
Phase 4 trial evaluating switching to Symtuza (darunavir/cobicistat/emtricitabine/tenofovir alafenamide) to improve tolerability and adheren…
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: Hepatitis C Treatment to Prevent HIV, Initiate Opioid Substitution Therapy, and Reduce Risky Behavior
This clinical trial update describes a study of hepatitis C treatment to prevent HIV infection, initiation of opioid substitution therapy wi…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Pharmacokinetics of Intracellular TFV-DP and FTC-TP in HIV-infected Adolescents
A completed pharmacokinetic study in HIV-infected adolescents evaluating intracellular TFV-DP and FTC-TP levels to understand drug exposure …
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Expedited Partner Therapy and the HIV Prevention Cascade [NA]
This document reports that a clinical trial evaluating expedited partner therapy in the HIV prevention cascade has completed, involving HIV …