HIV Infections

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: Comparison of Foscarnet Versus Vidarabine in the Treatment of Herpes Infection in Patients With AIDS Who Have Not Had Success With Acyclovir [Phase 3]

  Phase 3 trial comparing foscarnet to vidarabine for herpes infection in AIDS patients unresponsive to acyclovir has completed.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Randomized, Comparative Trial of Zidovudine (AZT) Versus 2',3'-Didehydro-3'-Deoxythymidine (Stavudine; d4T) in Children With HIV Infection [Phase 2]

  A Phase 2 randomized trial comparing zidovudine (AZT) to stavudine (d4T) in children with HIV infection has completed.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: Comparison of New Anti-HIV Drug Combinations in HIV-Infected Children Who Have Taken Anti-HIV Drugs [Phase 2]

  Phase 2 trial update comparing new anti-HIV drug combinations in HIV-infected children who have prior antiretroviral exposure.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children [Phase 2]

  Phase 2 trial comparing drugs to prevent serious bacterial infections in HIV-positive children has completed.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Study of Indinavir Sulfate Plus Zidovudine (AZT) Plus Lamivudine in HIV-Infected Patients Who Have Taken AZT for Six or More Months [Phase 3]

  Phase 3 trial evaluating the combination of indinavir sulfate with zidovudine (AZT) and lamivudine in HIV-infected patients who have used AZ…

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• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients [Phase 3]

  Phase 3 trial evaluating three drugs plus zidovudine for prevention of infections in HIV-infected patients has completed.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: The Treatment of Tuberculosis in HIV-Infected Patients [Phase 3]

  Phase 3 trial update on treating tuberculosis in HIV-infected patients has completed.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Phase II, Double-Blind Trial of Recombinant Human Nerve Growth Factor for Treatment of HIV-Associated Sensory Neuropathy [Phase 2]

  Phase II double-blind trial evaluating recombinant human nerve growth factor for HIV-associated sensory neuropathy has completed.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Double-Blind, Placebo-Controlled Trial of Paromomycin for Treatment of Cryptosporidiosis in Patients With Advanced HIV Disease and CD4 Counts Under 150 Cells/mm3 [Phase 2]

  Phase 2 double-blind, placebo-controlled trial of paromomycin for treating cryptosporidiosis in advanced HIV patients with CD4 count <150 ce…

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDS [Phase 3]

  Phase 3 trial comparing four treatment approaches for MAC disease in patients with AIDS; completed.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS [Phase 3]

  Phase 3 trial comparing trimetrexate plus leucovorin calcium rescue versus sulfamethoxazole-trimethoprim for Pneumocystis jirovecii pneumoni…

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: The Safety and Effectiveness of Zidovudine in the Treatment of Patients With Early AIDS Related Complex [Phase 3]

  Phase 3 clinical trial update evaluating the safety and effectiveness of Zidovudine in patients with early AIDS-related complex.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: Treatment With Combinations of Several Antiviral Drugs in Infants and Young Children With HIV Infection [Phase 2]

  Phase 2 clinical trial update evaluating combinations of several antiviral drugs in infants and young children with HIV infection; study sta…

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Comparative Study of a Combination of Zidovudine, Didanosine, and Double-Blinded Nevirapine Versus a Combination of Zidovudine and Didanosine [Phase 2]

  Phase 2 trial comparing a zidovudine/didanosine/nevirapine combo versus zidovudine/didanosine in HIV infections has completed.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women [Phase 3]

  Phase III randomized trial evaluating topical 5-fluorouracil maintenance therapy versus observation for high-grade cervical dysplasia in HIV…

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Study of Three Treatment Combinations Using Zidovudine Plus Lamivudine Plus Indinavir in HIV-Infected Patients [Phase 2]

  Phase 2 trial update evaluating three treatment combinations with zidovudine, lamivudine, and indinavir in HIV infections.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Phase II Clinical Trial to Evaluate the Immunogenicity and Reactogenicity of the Recombinant HIV-1 Envelope Vaccines SF-2 rgp120 (CHO) [Chiron Vaccines] in MF59 Adjuvant and MN rgp120/HIV-1 [VaxGen] in Alum Adjuvant in Healthy Adults [Phase 2]

  Phase II trial assessing immunogenicity and reactogenicity of recombinant HIV-1 envelope vaccines in MF59 and Alum adjuvants in healthy adul…

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDS [Phase 2]

  Phase 2 trial investigating itraconazole for treatment and prevention of histoplasmosis in patients with AIDS has completed.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Multicenter, Double Blind, Comparative Study of Zidovudine Alone Versus Zidovudine and Acyclovir as Treatment for HIV-Infected Patients With CD4+ Counts Less Than 200 Cells/mm3 [Phase 2]

  Phase 2 multicenter, double-blind study comparing zidovudine alone versus zidovudine plus acyclovir in HIV patients with CD4+ counts <200 ce…

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Comparison of Three Treatments for Advanced HIV Disease in Patients Who Have Received Nucleoside Therapy in the Past [Phase 2]

  Phase 2 clinical trial comparing three treatments for advanced HIV disease in patients previously treated with nucleoside therapy.

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Study of Tumor Necrosis Factor and Human Interferon-gamma in Patients With AIDS Related Complex [Phase 2]

  Phase 2 trial evaluating tumor necrosis factor and interferon-gamma in AIDS-related complex (HIV infection).

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Phase II Double-Blind Study of Delavirdine Mesylate ( U-90152 ) in Combination With Zidovudine ( AZT ) and/or Didanosine ( ddI ) Versus AZT and ddI Combination Therapy [Phase 2]

  A Phase II double-blind study evaluating delavirdine mesylate in combination with AZT and/or ddI versus AZT/ddI therapy for HIV infections h…

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: Immunologic and Virologic Consequences of Long-Term Highly Active Antiretroviral Therapy (HAART) in Subjects With Moderately Advanced HIV-1 Disease: A Follow-Up Study to ACTG 315 [Phase 2]

  Phase 2 follow-up study assessing immunologic and virologic effects of long-term HAART in moderately advanced HIV-1 disease (ACTG 315 follow…

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Study of Dideoxycytidine Plus Zidovudine (AZT) in HIV-Infected Children Who Have Taken AZT [Phase 2]

  Phase 2 trial update evaluating the combination of dideoxycytidine (ddC) and zidovudine (AZT) in HIV-infected children previously treated wi…

• CLINICAL_TRIALS trial_result · 2021-11-04
  Clinical Trial Update: A Phase II Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV vCP205 With or Without HIV-1 SF-2 RGP120 in HIV-1 Uninfected Adult Volunteers [Phase 2]

  Phase II safety and immunogenicity trial of live recombinant Canarypox ALVAC-HIV vCP205 with or without HIV-1 SF-2 gp120 in HIV-uninfected a…