HIV Infections
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: Immunomodulators on HIV-1 Reservoir [Phase 4]
A Phase 4 clinical trial update on immunomodulators for HIV-1 reservoir, with status currently unknown.
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: Uptake of Medical Male Circumcision Among Men With Sexually Transmitted Infections [NA]
A completed clinical trial assessing uptake of medical male circumcision among men with sexually transmitted infections, with results posted…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Women in Dual With Dolutegravir [Phase 3]
Phase 3 clinical trial update on women using dolutegravir in dual therapy for HIV infection; current status is unknown.
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Anti-HIV Medications for People Recently Infected With HIV [Phase 4]
Phase 4 trial update on anti-HIV medications for people recently infected with HIV; results completed and posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-08-25Clinical Trial Update: Study of Once Daily Elvucitabine Versus Lamivudine in Participants With a Documented M184V Mutation [Phase 1, Phase 2]
Clinical trial update comparing once-daily elvucitabine to lamivudine in participants with an M184V mutation in HIV infections; completed ph…
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CLINICAL_TRIALS trial_result · 2023-08-21Clinical Trial Update: Impact of CCR5 Blockade in HIV+ Kidney Transplant Recipients [Phase 2]
Phase 2 trial evaluating CCR5 blockade in HIV-positive kidney transplant recipients has completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: An Open-Label Treatment Protocol to Provide Continued Elvucitabine Treatment [Phase 2]
Open-label Phase 2 trial update describing continued elvucitabine treatment for HIV infections after completion of the study.
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CLINICAL_TRIALS trial_result · 2023-08-04Clinical Trial Update: Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs [Phase 3]
A Phase 3 safety and drug detection study evaluating Dapivirine vaginal ring and oral TRUVADA in breastfeeding mother-infant pairs has compl…
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CLINICAL_TRIALS trial_result · 2023-07-25Clinical Trial Update: Vitamin E for NASH Treatment in HIV Infected Individuals [Phase 2]
A Phase 2 trial studying vitamin E for treating nonalcoholic fatty liver disease and nonalcoholic steatohepatitis in individuals with HIV wa…
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Acceptability, Safety, and Use of Daily Truvada Pre-Exposure Prophylaxis in Adolescents [Phase 2]
Phase 2 trial update evaluating daily Truvada for HIV pre-exposure prophylaxis (PrEP) in adolescents, focusing on acceptability, safety, and…
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial [NA]
A completed efficacy trial evaluating YouTHrive for ART adherence in youth and young adults with HIV infections; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-06-05Clinical Trial Update: A Food-effect Study of the Pediatric Dispersible Tablet Formulations of TRIUMEQ® and DOVATO® in Healthy Adult Participants [Phase 1]
Phase 1 study assessing the food-effect of pediatric dispersible tablet formulations of TRIUMEQ and DOVATO in healthy adults; completed with…
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Evaluating the Safety and Antiviral Activity of Monoclonal Antibody VRC01 in Infants With HIV Receiving Combination Antiretroviral Therapy [Phase 1, Phase 2]
A Phase 1/2 clinical trial assessed the safety and antiviral activity of the monoclonal antibody VRC01 in infants with HIV on combination an…
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CLINICAL_TRIALS trial_result · 2023-05-19Clinical Trial Update: A Study Evaluating Implementation Strategies for Cabotegravir (CAB)+ Rilpivirine (RPV) Long-acting (LA) Injectables for Human Immunodeficiency Virus (HIV)-1 Treatment in European Countries [Phase 3]
Phase 3 study update on implementation strategies for cabotegravir plus rilpivirine long-acting injectables in HIV-1 treatment across Europe…
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: Reducing HIV Vulnerability Through A Multilevel Life Skills Intervention For Adolescent Men [NA]
Completed clinical trial evaluating a multilevel life skills intervention to reduce HIV vulnerability among adolescent men; results posted i…
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EMA approval · 2023-04-21EMA Authorised: Lamivudine Teva Pharma B.V. (lamivudine) — Teva B.V.
The EMA has authorised Lamivudine Teva Pharma B.V. for HIV infections, with Teva B.V. as the marketing authorization holder.
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EMA withdrawal · 2023-04-21EMA Application withdrawn: Raltegravir Viatris (raltegravir potassium) — Viatris Limited
The EMA has withdrawn the application for Raltegravir Viatris (raltegravir potassium) by Viatris Limited for HIV infections.
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EMA approval · 2023-04-18EMA Authorised: Emtriva (emtricitabine) — Gilead Sciences Ireland UC
Emtriva (emtricitabine) has been authorised by the EMA for HIV infections in the European Union.
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: Dolutegravir and Darunavir Evaluation in Adults Failing Therapy [Phase 4]
A Phase 4 clinical trial evaluating dolutegravir and darunavir in adults failing therapy for HIV infections.
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CLINICAL_TRIALS trial_result · 2023-04-14Clinical Trial Update: Evaluating the Safety and Pharmacokinetics of PC-1005 Administered Rectally to HIV-1 Seronegative Adults [Phase 1]
Phase 1 trial evaluating safety and pharmacokinetics of PC-1005 administered rectally in HIV-seronegative adults; completed with posted resu…
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CLINICAL_TRIALS trial_result · 2023-03-27Clinical Trial Update: The Effect Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) on Small Intestine Gut Wall [Phase 4]
Phase 4 clinical trial update evaluating the effect of tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) on the small inte…
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EMA withdrawal · 2023-03-21EMA Withdrawn: Lamivudine/Zidovudine Teva (lamivudine;zidovudine) — Teva Pharma B.V.
The EMA has withdrawn Lamivudine/Zidovudine Teva (lamivudine; zidovudine) from the market.
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CLINICAL_TRIALS trial_result · 2023-03-21Clinical Trial Update: PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects [Phase 1]
Phase 1 clinical trial assessing PET imaging of dopaminergic and serotonergic systems in HIV-positive individuals treated for depression; re…
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CLINICAL_TRIALS trial_result · 2023-03-15Clinical Trial Update: Valproic Acid and Its Effects on HIV Latent Reservoirs [Phase 2]
Phase 2 trial investigating valproic acid effects on HIV latent reservoirs has completed.
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Safety and Tolerability of PRO 140 in HIV Uninfected Male Volunteers [Phase 1]
Phase 1 study assessing safety and tolerability of PRO 140 in HIV-uninfected male volunteers has completed, with results posted.