HIV Infections
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Candidate HIV Vaccine [Phase 1]
A Phase 1 clinical trial of a candidate HIV vaccine sponsored by NIAID has completed. The study evaluated safety and immunogenicity in indiv…
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Clinical, Laboratory and Epidemiologic Pilot Studies of Individuals at High Risk for Viral-Associated Cancers
This news update reports on completed pilot studies assessing clinical, laboratory, and epidemiologic aspects in people at high risk for vir…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Raltegravir vs. Lopinavir/Ritonavir, Both in Combination With Truvada, in HIV+ Treatment Naive Individuals [Phase 4]
Phase 4 trial comparing raltegravir to lopinavir/ritonavir, both with Truvada, in treatment-naive HIV-infected individuals; study terminated…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Trizivir Vs. Kaletra and Combivir for the Prevention of Mother-to-Child Transmission of HIV [Phase 2]
Phase 2 trial comparing Trizivir, Kaletra, and Combivir for prevention of mother-to-child transmission of HIV; study completed with results …
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EMA withdrawal · 2017-05-29EMA Withdrawn: Vitekta (elvitegravir) — Gilead Sciences International Ltd
EMA withdrawn status for Vitekta (elvitegravir) by Gilead Sciences International Ltd. Indicates withdrawal of the medicinal product in Europ…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: The ADAPT Study: Use of Emtricitabine and Tenofovir Disoproxil Fumarate for Pre-Exposure Prophylaxis (PrEP) [Phase 2]
The HIV Prevention Trials Network completed the Phase 2 ADAPT study evaluating emtricitabine/tenofovir disoproxil fumarate as pre-exposure p…
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: Evaluating the Safety, Pharmacokinetics, and Antiviral Activity of a Human Monoclonal Antibody (VRC01) in HIV-Infected Adults Undergoing a Brief Treatment Interruption [Phase 1]
Phase 1 clinical trial evaluating safety, pharmacokinetics, and antiviral activity of the human monoclonal antibody VRC01 in HIV-infected ad…
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Pharmacokinetics, Safety, and Efficacy of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate Single Tablet Regimen (STR) in Adolescents [Phase 2, Phase 3]
Phase 2/3 trial update presents pharmacokinetics, safety, and efficacy data for the single-tablet Regimen of elvitegravir/cobicistat/emtrici…
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Assessment of Pre-Exposure Prophylaxis (PrEP) Administered at Sexually Transmitted Disease (STD) Clinics [NA]
Completed clinical trial assessing PrEP administration at STD clinics; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: Immunologic Memory (Supp. of ATN 024) [Phase 4]
Phase 4 clinical trial update on immunologic memory related to ATN 024 for HIV infections; the study status is COMPLETED.
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: C2P (With Venues): Connect to Protect® Partnerships For Youth Prevention Interventions
This is a completed status update for the Connect to Protect (C2P) Partnerships For Youth Prevention Interventions trial, sponsored by the U…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Adherence and Acceptability to and Blood Levels of Tenofovir Gel and Tablets in HIV Uninfected Women [Phase 2]
Phase 2 trial update evaluating adherence, acceptability, and blood levels of tenofovir gel and tablets for HIV-uninfected women; study comp…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: A Pilot Project of Virologic, Pharmacologic and Immunologic Correlates of Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution Following Maraviroc Therapy [Phase 4]
Phase 4 pilot study evaluating virologic, pharmacologic, and immunologic correlates of gastrointestinal-associated lymphoid tissue immune re…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: Reduction of Drug Use and HIV Risk Among Out-of-Treatment Methamphetamine Users [NA]
A completed clinical trial from the University of Colorado, Denver evaluating strategies to reduce methamphetamine use and HIV risk among ou…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Drug Treatment Combined With Drug and Risk Reduction Counseling to Prevent of HIV Infection and Death Among Injection Drug Users [Phase 3]
Phase 3 trial evaluating drug treatment plus risk reduction counseling to prevent HIV infection and death among injection drug users; study …
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CLINICAL_TRIALS approval · 2016-11-30Clinical Trial Update: An Open Label Safety Study of Tipranavir Co-administered With Low-dose Ritonavir in Patients With Advanced HIV-1 Infection and Limited Treatment Options.
An open-label safety study of tipranavir boosted with low-dose ritonavir in advanced HIV-1 infection with limited treatment options, with ma…
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Phase I Trial of an Intervention to Increase Condom Use by HIV-Discordant Couples [Phase 1]
This update reports the completion of a Phase I clinical trial evaluating an intervention aimed at increasing condom use among HIV-discordan…
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: Preventing Sexual Transmission of HIV With Anti-HIV Drugs [Phase 3]
Phase 3 trial update on preventing sexual transmission of HIV using anti-HIV drugs.
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CLINICAL_TRIALS trial_result · 2016-09-20Clinical Trial Update: TMC114-C202: A Study of Safety, Efficacy, and Tolerability of TMC114 and Low Dose Ritonavir in HIV-1 Infected Patients [Phase 2]
A Phase 2 study (TMC114-C202) assessing safety, efficacy, and tolerability of TMC114 (darunavir) boosted with low-dose ritonavir in HIV-1 in…
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Viral Activation Transfusion Study (VATS) [NA]
The Viral Activation Transfusion Study (VATS) sponsored by NHLBI has completed, investigating AIDS/HIV-related infections and cytomegaloviru…
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Evaluate Weight Gain Using 2 Different Formulations of Megestrol Acetate Oral Suspension for AIDS-related Weight Loss [Phase 2]
Phase 2 trial evaluating two formulations of megestrol acetate oral suspension for AIDS-related weight loss completed; results posted in 201…
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CLINICAL_TRIALS research · 2016-04-14Clinical Trial Update: Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection (P2C2)
NHLBI-sponsored pediatric study on pulmonary and cardiovascular complications of vertically transmitted HIV infection has completed.
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CLINICAL_TRIALS research · 2016-04-06Clinical Trial Update: Eliciting Affect in Teens in a Virtual World (Project AVATAR) [Phase 1, Phase 2]
Phase 1/2 clinical trial update for Project AVATAR, a Rhode Island Hospital study exploring eliciting affect in teens in a virtual world for…
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CLINICAL_TRIALS trial_result · 2016-04-05Clinical Trial Update: Atazanavir Used in Combination With Other Anti-HIV Drugs in HIV-Infected Infants, Children, and Adolescents [Phase 1, Phase 2]
Phase 1/2 trial of atazanavir in combination with other anti-HIV drugs in HIV-infected infants, children, and adolescents completed with res…
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CLINICAL_TRIALS trial_result · 2016-03-10Clinical Trial Update: Safety and Efficacy of E/C/F/TDF Versus RTV-Boosted ATV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment-Naive Women [Phase 3]
Phase 3 trial comparing E/C/F/TDF with RTV-boosted ATV plus FTC/TDF in ART-naive women with HIV-1, assessing safety and efficacy.