HIV Infections
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CLINICAL_TRIALS trial_result · 2010-06-14Clinical Trial Update: A Study to Assess the Long-term Efficacy (24 Weeks) of MPC-4326 in Combination With a 2-3 Drug OBR Relative to the Efficacy of a 3-4 Drug ARV Regimen in Treatment Experienced HIV-1 Infected Subjects Who Are Failing Current Antiretroviral Therapy [Phase 2]
Phase 2 study evaluating the long-term efficacy of MPC-4326 in combination with an optimized background regimen versus a 3-4 drug antiretrov…
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CLINICAL_TRIALS trial_result · 2010-04-26Clinical Trial Update: TMC114-C227: A Study to Evaluate the Effectiveness and Safety of TMC114 (Darunavir) With a Low Dose of Ritonavir as Monotherapy (no Other Anti-HIV Drugs Will be Given) in Patients Who Have Never Been Treated With Antiretrovirals (Anti-HIV Drugs) Previously [Phase 2]
Phase 2 trial evaluating darunavir (TMC114) with low-dose ritonavir as monotherapy in antiretroviral-naive HIV patients was terminated.
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CLINICAL_TRIALS trial_result · 2010-03-11Clinical Trial Update: Culturally-Tailored HIV Risk Reduction for African-American MSM [NA]
A completed clinical trial evaluating culturally tailored HIV risk reduction for African-American men who have sex with men.
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CLINICAL_TRIALS trial_result · 2010-02-05Clinical Trial Update: Drug Interaction Study of Famotidine and Atazanavir With Ritonavir in HIV-Infected Patients [Phase 4]
A Phase 4 clinical trial evaluated drug interactions between famotidine and the HIV protease inhibitor atazanavir boosted with ritonavir in …
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CLINICAL_TRIALS trial_result · 2009-08-11Clinical Trial Update: Study of Pregabalin Versus Placebo in the Treatment of Nerve Pain Associated With HIV Neuropathy [Phase 3]
Phase 3 trial comparing pregabalin to placebo for nerve pain in HIV-associated neuropathy completed with results posted in 2009.
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CLINICAL_TRIALS trial_result · 2009-03-23Clinical Trial Update: Open Label Safety And Efficacy Study Of Pregabalin In Subjects With Nerve Pain Asociated With Human Immunodeficiency Virus (HIV) Neuropathy [Phase 3]
Open-label safety and efficacy study of pregabalin for nerve pain in HIV-related peripheral neuropathy completed with results posted in 2009…
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CLINICAL_TRIALS trial_result · 2009-02-11Clinical Trial Update: VENICE Study Nevirapine Full Dose/Dose Escalation [Phase 4]
The VENICE Phase 4 trial evaluated full-dose versus dose-escalation nevirapine regimens in HIV-infected participants; the study is completed…
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CLINICAL_TRIALS trial_result · 2008-10-09Clinical Trial Update: Effect of an Online Video-Based Intervention to Increase HIV Testing in Men Who Have Sex With Men in Peru [NA]
This completed clinical trial evaluated an online video-based intervention to increase HIV testing among men who have sex with men in Peru.
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CLINICAL_TRIALS trial_result · 2008-09-17Clinical Trial Update: Treatment Intensification for HIV Infected Patients With Multi-Drug Resistant Virus [NA]
An update on an NIAID clinical trial evaluating intensified treatment for HIV infections with multi-drug resistant virus; no results or curr…
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CLINICAL_TRIALS trial_result · 2008-08-26Clinical Trial Update: A Phase I/II Trial of Ribavirin (With Escalation) + Isoprinosine in Asymptomatic HIV-Viremic Patients [Phase 1]
This entry describes a Phase I/II trial evaluating ribavirin (with escalation) plus isoprinosine in asymptomatic HIV-viremic patients. The s…
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: The Pharmacokinetics of Zidovudine and Oxazepam Alone and in Combination in the HIV-Infected Patient [Phase 1]
This Phase 1 pharmacokinetic study assesses Zidovudine and Oxazepam when given alone and in combination in HIV-infected patients.
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: The Safety and Effectiveness of BI-RG-587 in HIV-Infected Patients [Phase 1]
This Phase 1 trial assessed the safety and preliminary effectiveness of BI-RG-587 in HIV-infected patients and has completed the study.
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CLINICAL_TRIALS trial_result · 2008-07-04Clinical Trial Update: SWEET: Once Daily Truvada Versus Twice Daily Combivir for the Treatment of HIV Infection [Phase 3]
Phase 3 SWEET trial comparing once-daily Truvada to twice-daily Combivir for HIV infection has completed.
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CLINICAL_TRIALS trial_result · 2008-06-05Clinical Trial Update: Cotrimoxazole Prophylaxis Cessation Study Among Stabilized HIV-Infected Adult Patients on HAART in Entebbe, Uganda [Phase 4]
A Phase 4 study evaluating cessation of cotrimoxazole prophylaxis in adults with HIV infection stabilized on HAART in Entebbe, Uganda. The t…
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CLINICAL_TRIALS trial_result · 2008-03-06Clinical Trial Update: Study of NGX-4010 for Treatment of Painful HIV-Associated Neuropathy [Phase 3]
A Phase 3 trial of NGX-4010 (capsaicin patch) for painful HIV-associated neuropathy was terminated.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Pilot Study of the Combination of Retinoic Acid and Interferon-Alpha2a for the Treatment of Lymphoproliferative Disorders in Children With Immunodeficiency Syndromes [Phase 2]
A completed Phase 2 pilot trial evaluating the combination of all-trans retinoic acid and interferon-alpha2a for lymphoproliferative disorde…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Pilot Study of Adherence to Oral Medication and Health Beliefs of Adolescents With HIV and Their Mothers
A completed pilot clinical trial evaluating adherence to oral antiretroviral therapy and health beliefs among adolescents with HIV and their…
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CLINICAL_TRIALS trial_result · 2008-01-25Clinical Trial Update: Mindfulness Meditation Training in HIV [Phase 2]
Phase 2 trial of mindfulness meditation training for HIV infections has been completed.
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CLINICAL_TRIALS trial_result · 2007-11-01Clinical Trial Update: SHARE: Simple HAART With Abacavir, Reyataz, and Epivir [Phase 4]
Phase 4 trial update of a simple HAART regimen using abacavir, atazanavir, and lamivudine for HIV infection with lipodystrophy; the current …
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CLINICAL_TRIALS trial_result · 2007-10-02Clinical Trial Update: The Safety and Effectiveness of Megace in HIV-Infected Women [Phase 4]
Phase 4 clinical trial update evaluating the safety and effectiveness of Megace (megestrol acetate) in HIV-infected women; the study is list…
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CLINICAL_TRIALS trial_result · 2007-09-18Clinical Trial Update: Promoting Adherence to Anti-HIV Drug Regimens [NA]
A completed clinical trial update from NIAID focusing on promoting adherence to antiretroviral regimens for HIV infections.
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CLINICAL_TRIALS trial_result · 2007-05-11Clinical Trial Update: Safety, Tolerance, Pharmacokinetic and Antiviral Study of Amdoxovir in Combination With Zidovudine in Adults With HIV [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated safety, tolerability, pharmacokinetics, and antiviral activity of Amdoxovir in combination with Zidovu…
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CLINICAL_TRIALS trial_result · 2007-02-16Clinical Trial Update: Randomized Controlled Trial of Stress Management Training in HIV [Phase 3]
A Phase 3 randomized trial evaluating stress management training in HIV infections has completed.
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CLINICAL_TRIALS trial_result · 2006-08-18Clinical Trial Update: The Use of Reiki for Patients With Advanced AIDS [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating Reiki as a complementary therapy for patients with advanced AIDS. Th…
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CLINICAL_TRIALS trial_result · 2006-08-15Clinical Trial Update: A Study of Two Different Doses of ABT-378/Ritonavir in HIV-Infected Patients Who Have Taken Protease Inhibitors and Non-Nucleoside Reverse Transcriptase Inhibitors [Phase 3]
Phase 3 clinical trial update evaluating two different doses of lopinavir/ritonavir in HIV-infected patients who have previously taken prote…