HIV Infection
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Adjuvant 5-Fluorouracil Following Thermal Ablation to Improve HPV Treatment Outcomes in Women With HIV in Kenya [Phase 2]
A Phase 2 clinical trial in Kenya is evaluating adjuvant 5-fluorouracil after thermal ablation to improve HPV-related outcomes in women with…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Pilot RCT and Interview Study on an HIV Chatbot in Nigeria [NA]
This document reports a pilot randomized controlled trial and interview study evaluating an HIV chatbot in Nigeria, sponsored by Christoph P…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Assessment of Metformin for Restoration of Immune Homeostasis in HIV+ and HIV- Individuals With a History of Injection Drug Use [Phase 4]
Phase 4 clinical trial update evaluating metformin for restoring immune homeostasis in HIV-positive and HIV-negative individuals with a hist…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women
A clinical trial is investigating the combined impact of menopause and HIV on cardiovascular disease risk in women and is currently recruiti…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Study of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV [Phase 2]
Phase 2 trial of the oral TLR8 agonist Selgantolimod (GS-9688) on HBsAg in participants with chronic hepatitis B and HIV has completed.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Exploratory Study of LP-98 for Injection in ART-Naive HIV-Infected Individuals [Phase 1, Phase 2]
An exploratory Phase 1/2 clinical trial evaluating LP-98 injections in ART-naive individuals with HIV; the study is currently in recruitment…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Implementing PrEP for Women Who Inject Drugs [NA]
Clinical trial update on implementing pre-exposure prophylaxis (PrEP) for women who inject drugs; the study is currently active but not recr…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission [Phase 2]
A Phase 2 clinical trial is evaluating combination HIV-specific broadly neutralizing monoclonal antibodies with antiretroviral therapy initi…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV [Phase 2, Phase 3]
Phase 2/3 pediatric trial evaluating cobicistat-boosted atazanavir, cobicistat-boosted darunavir, and emtricitabine/tenofovir alafenamide fo…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study of very early intensive antiretroviral therapy for infants with HIV to achieve …
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Lower Intersecting HIV-related Stigmas to Facilitate Treatment as Prevention (LIFT) [NA]
The LIFT clinical trial is investigating whether reducing intersecting HIV-related stigmas can facilitate treatment as prevention, and is cu…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Spatial Analysis of Hotspots and Targeted Injection Settings Pilot Intervention for HIV Prevention Among People Who Inject Drugs [NA]
A clinical trial update describing a pilot intervention that uses spatial analysis of hotspots and targeted injection settings to prevent HI…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Among Justice-involved Black Men Who Have Sex With Men and Other Key Populations [NA]
The trial registry entry describes the J-RISE study, which aims to implement strategies to eliminate social and structural barriers to HIV s…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Intensive Combination Approach to Rollback the Epidemic in Nigerian Adolescents: UH3 Phase [NA]
Clinical trial update for a completed UH3-phase study in Nigerian adolescents evaluating an intensive combination approach to HIV infection;…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Adaptation and Implementation of an Evidence-based Approach to Advance HIV Prevention and Care [NA]
A UCLA-led clinical trial update on adapting and implementing an evidence-based approach to advance HIV prevention and care, with recruitmen…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes [NA]
This clinical trial is currently recruiting to evaluate a harm reduction strategy for people with HIV who smoke cigarettes. The study is spo…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection [Phase 2]
Phase 2 clinical trial evaluating surgery for early-stage anal canal cancer or perianal cancer in HIV-infected patients; the study has compl…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: HIV Engagement and Adolescent Depression Support (HEADS-UP) [NA]
A completed UNC-led clinical trial evaluating HIV engagement and support for adolescents with depression and anxiety.
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: A Study to Assess the Safety, Tolerability and Pharmacokinetics of Lipovirtide in HIV-infected Patients [Phase 1]
Phase 1 clinical trial evaluating the safety, tolerability, and pharmacokinetics of Lipovirtide in HIV infection; the study has completed.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Clinical Trial to Evaluate the Safety and Immunogenicity of Ferritin Nanoparticles Expressing Native-like HIV-1 Envelope Trimers Followed by Boost With mRNA Lipid Nanoparticles Encoding a Native-like HIV-1 Envelope Trimer in Adults Without HIV [Phase 1]
Phase 1 trial to assess the safety and immunogenicity of ferritin nanoparticle HIV envelope trimers followed by an mRNA lipid nanoparticle b…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Working Memory Training for People Aging With HIV [EARLY_Phase 1]
Early phase 1 trial assessing working memory training for people aging with HIV has completed.
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Telehealth Delivery (Tele-B6) [NA]
Tele-B6 is a telehealth-delivery trial that completed and posted results in HIV infection (HIV-seropositive) individuals, including particip…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Ending the HIV Epidemic: An All-facility Intervention for Patient and Healthcare Staff Well-being [NA]
This clinical trial update notes recruitment for an all-facility intervention aimed at improving patient and healthcare staff well-being and…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Natural History Study of Kaposi Sarcoma
The National Cancer Institute-sponsored natural history study of Kaposi sarcoma is currently recruiting. The study will observe disease prog…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: ACT for HIV-Positive Men [NA]
A clinical trial evaluating Acceptance and Commitment Therapy (ACT) for stress and anxiety in HIV-positive men has been terminated.