Heroin Dependence
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing Regimens [Phase 2]
Phase 2 trial completed comparing three dosing regimens for heroin/opioid dependence to evaluate efficacy and safety.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Addition of Naltrexone to Methadone Taper [Phase 2]
A Phase 2 clinical trial evaluating the addition of naltrexone to a methadone taper for heroin dependence and related opioid/substance use d…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Treatment Efficacy for Drug Abuse and AIDS Prevention - 1 [Phase 2]
Phase 2 trial results assess the efficacy of a treatment for cocaine-related disorders and heroin dependence, with AIDS prevention objective…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Buprenorphine/Naloxone Versus Clonidine for Outpatient Opiate Detoxification - 1 [Phase 3]
Phase 3 trial comparing Buprenorphine/Naloxone versus Clonidine for outpatient opiate detoxification has completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Buprenorphine/Naloxone Versus Clonidine for Inpatient Opiate Detoxification - 1 [Phase 3]
This is a Phase 3 clinical trial comparing buprenorphine/naloxone to clonidine for inpatient detoxification in heroin and morphine dependenc…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Effects of Buspirone in Opiate Withdrawal [Phase 4]
A Phase 4 clinical trial evaluated the effects of buspirone on opiate withdrawal in individuals with heroin dependence; the study has comple…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Buprenorphine and Naloxone Combination Study - 10 [Phase 1]
This update reports the completion of a Phase 1 clinical trial evaluating a buprenorphine/naloxone combination for heroin dependence and opi…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals
A completed clinical trial evaluated whether a pre-session supplemental dose of hydromorphone influences drug-seeking behavior in opioid-dep…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: The Therapeutic Workplace Initiation Study [NA]
Clinical trial update for The Therapeutic Workplace Initiation Study completed; results posted in 2016. Conditions include cocaine-related d…
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CLINICAL_TRIALS trial_result · 2016-11-28Clinical Trial Update: Acute and Short-term Effects of Cannabidiol Admin on Cue-induced Craving in Drug-abstinent Heroin Dependent Humans [Phase 2]
Phase 2 clinical trial investigating acute and short-term effects of cannabidiol administration on cue-induced craving in drug-abstinent her…
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CLINICAL_TRIALS trial_result · 2016-11-09Clinical Trial Update: Pharmacogenomics Study of Sleep Disturbance and Neurocognitive Impairments in the Opioid Addicts
This clinical trial update reports the completion of a pharmacogenomics study examining sleep disturbance and neurocognitive impairments in …
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CLINICAL_TRIALS trial_result · 2016-09-29Clinical Trial Update: Variance of Oral Methadone Dosage: Description of Implicated Factors
This update describes factors implicated in the variability of oral methadone dosing observed in a completed trial for heroin dependence. It…
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CLINICAL_TRIALS trial_result · 2016-06-07Clinical Trial Update: Study to Assess Longer-term Opioid Medication Effectiveness (SALOME) [Phase 3]
The SALOME Phase 3 trial evaluating longer-term opioid medication effectiveness for opioid dependence and heroin dependence has completed.
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CLINICAL_TRIALS trial_result · 2016-01-11Clinical Trial Update: Buprenorphine Maintenance Treatment of Opioid Dependence in Primary Care: A Randomized Clinical Trial [Phase 2, Phase 3]
Randomized trial assessing buprenorphine maintenance treatment for opioid dependence in primary care settings, with results posted after com…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Methadone Maintenance Outcome Study in Taiwan: 5-year Follow-up
Five-year follow-up update of a methadone maintenance study in Taiwan for heroin dependence, reporting long-term outcomes such as mortality,…
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CLINICAL_TRIALS trial_result · 2015-09-04Clinical Trial Update: Mirtazapine as a Treatment for Co-Occurring Opioid and ATS Dependence in Malaysia [Phase 3]
A Phase 3 trial is investigating mirtazapine for co-occurring heroin (opioid) and amphetamine dependence in Malaysia; the current status is …
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CLINICAL_TRIALS trial_result · 2014-12-11Clinical Trial Update: Diversion to Treatment for Injection Drug Users Arrested for Possession of Heroin [Phase 1]
Phase 1 clinical trial update on diversion to treatment for injection drug users arrested for heroin possession, involving conditions includ…
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: Depot Naltrexone Mechanism of Action in Heroin Dependent Patients Using fMRI and SPECT [Phase 4]
Phase 4 study investigating the mechanism of action of depot naltrexone in heroin-dependent patients using functional MRI and SPECT imaging.
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CLINICAL_TRIALS trial_result · 2012-10-24Clinical Trial Update: Naltrexone and Adrenergic Agents to Reduce Heroin Use in Heroin Addicts [Phase 2]
A Phase 2 clinical trial update evaluating naltrexone combined with adrenergic agents to reduce heroin use in individuals with heroin depend…
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CLINICAL_TRIALS trial_result · 2012-06-05Clinical Trial Update: Effects of Stress and Other Factors on Opiate Drug Choice.
This completed clinical trial studied how stress and other factors influence opiate drug choice in individuals with heroin dependence and op…
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CLINICAL_TRIALS trial_result · 2012-06-05Clinical Trial Update: Effects of Post-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals
A completed clinical trial examined whether post-session supplemental hydromorphone affects drug-seeking behavior in heroin-dependent indivi…
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CLINICAL_TRIALS trial_result · 2012-01-13Clinical Trial Update: Opiate Dependence: Combined Naltrexone/Behavior Therapy - 1 [Phase 2]
Phase 2 clinical trial of combined naltrexone and behavioral therapy for heroin dependence has completed.
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CLINICAL_TRIALS research · 2011-03-11Clinical Trial Update: Effect Study of Optimized Intervention to Heroin Addicts [NA]
Clinical trial update on an optimized intervention for heroin dependence conducted by Shanghai Mental Health Center; current status is unkno…
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CLINICAL_TRIALS research · 2008-09-25Clinical Trial Update: Effect of Stress on Heroin-Related Memory Retrieval [NA]
This completed clinical trial studied whether stress influences the retrieval of heroin-related memories in individuals with heroin dependen…
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CLINICAL_TRIALS trial_result · 2006-10-24Clinical Trial Update: A Stepwise Strategy Utilizing Buprenorphine and Methadone [Phase 4]
Completed Phase 4 trial evaluating a stepwise strategy using buprenorphine and methadone for heroin dependence.