Hepatocellular Carcinoma

• CLINICAL_TRIALS withdrawal · 2014-12-02
  Clinical Trial Update: TACE With or Without Radiation Therapy in Treating Patients With Stage A-C Liver Cancer [Phase 2]

  A Phase 2 trial evaluating transarterial chemoembolization (TACE) with or without radiation therapy for stage I–III hepatocellular carcinoma…

• CLINICAL_TRIALS trial_result · 2014-12-01
  Clinical Trial Update: Sorafenib as Adjuvant Treatment in the Prevention Of Recurrence of Hepatocellular Carcinoma (STORM) [Phase 3]

  Phase 3 trial update for sorafenib as adjuvant therapy in hepatocellular carcinoma (STORM) completed; results posted in 2014.

• CLINICAL_TRIALS trial_result · 2014-11-24
  Clinical Trial Update: A Study of Adoptive Immunotherapy With Autologous Tumor Infiltrating Lymphocytes in Solid Tumors [Phase 1]

  A Phase 1 study evaluating autologous tumor-infiltrating lymphocytes (TIL) therapy in solid tumors, including nasopharyngeal carcinoma, hepa…

• CLINICAL_TRIALS research · 2014-11-21
  Clinical Trial Update: Thymalfasin Adjuvant Therapy in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC) After Curative Resection [Phase 4]

  Phase 4 clinical trial update on thymalfasin (thymosin alpha-1) as adjuvant therapy after curative resection in HBV-related hepatocellular c…

• FDA approval · 2014-11-10
  FDA Approved: STIVARGA — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)

  FDA approved a supplemental application for Stivarga (regorafenib) submitted by Bayer HealthCare Pharmaceuticals Inc. The action updates the…

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• CLINICAL_TRIALS research · 2014-11-07
  Clinical Trial Update: Diffusion-Weighted Magnetic Resonance Imaging [Phase 2]

  Clinical trial update for a Phase 2 diffusion-weighted MRI study in hepatocellular carcinoma and spine metastasis; current status is unknown…

• CLINICAL_TRIALS trial_result · 2014-10-30
  Clinical Trial Update: Doxorubicin and Bortezomib in Treating Patients With Liver Cancer [Phase 2]

  Phase 2 trial evaluating the combination of doxorubicin and bortezomib for hepatocellular carcinoma has completed, with results posted in 20…

• CLINICAL_TRIALS trial_result · 2014-10-27
  Clinical Trial Update: Global Study Looking at the Combination of RAD001 Plus Best Supportive Care (BSC) and Placebo Plus BSC to Treat Patients With Advanced Hepatocellular Carcinoma. [Phase 3]

  Phase 3 global trial evaluating everolimus (RAD001) plus best supportive care versus placebo plus best supportive care in advanced hepatocel…

• CLINICAL_TRIALS withdrawal · 2014-10-22
  Clinical Trial Update: Study of Sorafenib, Gemcitabine, and Cisplatin in Advanced Hepatocellular Carcinoma (HCC) [Phase 2]

  A Phase 2 study evaluating sorafenib with gemcitabine and cisplatin for advanced hepatocellular carcinoma has been withdrawn.

• CLINICAL_TRIALS trial_result · 2014-10-03
  Clinical Trial Update: Study of GC33 and Sorafenib in Combination in Advanced or Metastatic Liver Cancer (Hepatocellular Carcinoma) [Phase 1]

  This document reports a completed Phase 1 study evaluating the combination of GC33 and sorafenib for advanced or metastatic hepatocellular c…

• CLINICAL_TRIALS research · 2014-10-01
  Clinical Trial Update: A Prospective Control Study of Cidan Capsule Combined With TACE in Hepatocellular Carcinoma [Phase 4]

  This clinical trial update outlines a Phase 4 prospective control study evaluating Cidan Capsule combined with transarterial chemoembolizati…

• CLINICAL_TRIALS trial_result · 2014-09-16
  Clinical Trial Update: Transarterial Chemotherapy Compared With Oral Chemotherapy in the Treatment of Advanced Hepatocellular Carcinoma [Phase 2, Phase 3]

  This document reports a clinical trial comparing transarterial chemotherapy to oral chemotherapy for advanced hepatocellular carcinoma, span…

• CLINICAL_TRIALS research · 2014-09-12
  Clinical Trial Update: 18F-FluoroethylCholine Positron Emission Tomography: a Promising Diagnostic Tool for Hepatocellular Carcinoma

  Clinical trial update evaluating 18F-FluoroethylCholine PET as a diagnostic tool for hepatocellular carcinoma.

• CLINICAL_TRIALS trial_result · 2014-09-04
  Clinical Trial Update: Tenofovir Antiviral Therapy Following Transarterial Chemoembolization for HBV Related Hepatocellular Carcinoma [Phase 3]

  Phase 3 trial of Tenofovir antiviral therapy following transarterial chemoembolization for HBV-related hepatocellular carcinoma has been ter…

• CLINICAL_TRIALS trial_result · 2014-08-29
  Clinical Trial Update: A Study of Avastin (Bevacizumab) and Transarterial Chemoembolisation (TACE) Treatment in Patients With Liver Cancer [Phase 2]

  This Phase 2 trial evaluates bevacizumab (Avastin) in combination with transarterial chemoembolization (TACE) for hepatocellular carcinoma, …

• CLINICAL_TRIALS trial_result · 2014-07-30
  Clinical Trial Update: Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma [Phase 3]

  A Phase 3 trial evaluating immunosuppression in liver transplant patients with hepatocellular carcinoma has completed. The update notes the …

• CLINICAL_TRIALS trial_result · 2014-07-29
  Clinical Trial Update: Preliminary Results for the Double-dose Adenovirus-mediated Adjuvant Therapy Improving Outcome of Liver Transplantation in Patients With Advanced Hepatocellular Carcinoma [Phase 2]

  Phase 2 trial results assess a double-dose adenovirus-mediated adjuvant therapy given after liver transplantation in patients with advanced …

• CLINICAL_TRIALS withdrawal · 2014-07-22
  Clinical Trial Update: Associating Liver Partition With Portal Vein Ligation For Staged Hepatectomy (ALPPS) or Portal Vein Occlusion in Treating Patients With Liver Cancer [Phase 2]

  The Phase 2 clinical trial evaluating ALPPS or portal vein occlusion for hepatocellular carcinoma has been withdrawn.

• CLINICAL_TRIALS withdrawal · 2014-07-16
  Clinical Trial Update: Radiofrequency Ablation in Treating Patients With Liver Cancer (Hepatocellular Carcinoma) [Phase 2]

  The Phase 2 trial evaluating radiofrequency ablation for hepatocellular carcinoma (liver cancer) has been withdrawn.

• CLINICAL_TRIALS trial_result · 2014-07-16
  Clinical Trial Update: Trial of TG4023 Combined With Flucytosine in Liver Tumors [Phase 1]

  A Phase 1 study evaluating TG4023 in combination with flucytosine for hepatocellular carcinoma has completed.

• CLINICAL_TRIALS trial_result · 2014-07-08
  Clinical Trial Update: Determine the Pharmacokinetics and Safety of Brivanib in Chinese Subjects With Advanced Primary Liver Cancer (Hepatocellular Carcinoma: HCC) [Phase 1]

  A Phase 1 pharmacokinetic and safety study evaluating Brivanib in Chinese patients with advanced hepatocellular carcinoma. The trial status …

• CLINICAL_TRIALS research · 2014-07-04
  Clinical Trial Update: TH-302 Plus Doxorubicin Delivered by Trans-Arterial Chemoembolization (TACE) in Patients With Hepatocellular Carcinoma [Phase 1]

  Phase 1 trial update of TH-302 (evofosfamide) plus doxorubicin delivered via trans-arterial chemoembolization for hepatocellular carcinoma. …

• CLINICAL_TRIALS trial_result · 2014-07-03
  Clinical Trial Update: Study of IMC-1121B (Ramucirumab) in Participants With Liver Cancer Who Have Not Previously Been Treated With Chemotherapy [Phase 2]

  A Phase 2 study of ramucirumab (IMC-1121B) in untreated hepatocellular carcinoma has completed, with results posted in 2014.

• CLINICAL_TRIALS withdrawal · 2014-06-26
  Clinical Trial Update: Efficacy of Radiation Therapy and Transarterial Chemoembolization (TACE) to Treat Hepatocellular Carcinoma (HCC) [Phase 2]

  Phase 2 trial evaluating radiation therapy in combination with transarterial chemoembolization for hepatocellular carcinoma has been withdra…

• CLINICAL_TRIALS trial_result · 2014-06-18
  Clinical Trial Update: Selection Criteria for Safe Hepatectomy for Hepatocellular Carcinoma

  A completed clinical trial from the University of Milan evaluating selection criteria for safe hepatectomy in patients with hepatocellular c…