Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2023-05-03Clinical Trial Update: Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery [Phase 4]
A Phase 4 clinical trial evaluating anesthetic agents and acute kidney injury after liver resection has been withdrawn.
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CLINICAL_TRIALS trial_result · 2023-04-26Clinical Trial Update: Regorafenib After Progression on Atezolizumab Plus Bevacizumab in Advanced HCC [Phase 2]
Phase 2 clinical trial evaluating regorafenib after progression on atezolizumab plus bevacizumab in advanced hepatocellular carcinoma is ong…
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CLINICAL_TRIALS trial_result · 2023-04-26Clinical Trial Update: Lenalidomide to Reverse Drug Resistance After First-line Treatment of Advanced HCC [Phase 2]
A Phase 2 trial evaluating lenalidomide to reverse drug resistance after first-line treatment in advanced hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2023-04-20Clinical Trial Update: HAIC Combined With Cadonilimab and Bevacizumab as First-line Therapy in Unresectable Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating HAIC combined with cadonilimab and bevacizumab as first-line therapy for unresectable hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2023-04-19Clinical Trial Update: Ablation Combined With PD-1 in HCC: Phase II Study [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating ablation combined with PD-1 blockade for hepatocellular carcinoma (HCC).
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: A Phase 2 Study of Cabozantinib in Japanese Participants With Advanced Hepatocellular Carcinoma [Phase 2]
Phase 2 trial assessing cabozantinib in Japanese patients with advanced hepatocellular carcinoma has completed with posted results.
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FDA approval · 2023-04-12FDA Approved: SORAFENIB — Original Application (Torrent Pharmaceuticals Limited)
The FDA approved Torrent Pharmaceuticals' original ANDA for sorafenib, a generic version of Nexavar, expanding access to the cancer therapy.
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CLINICAL_TRIALS trial_result · 2023-04-05Clinical Trial Update: Cabozantinib and Pembrolizumab for the First-Line Treatment of Advanced Liver Cancer [Phase 2]
Phase 2 trial evaluating cabozantinib with pembrolizumab as first-line therapy for advanced hepatocellular carcinoma was terminated; results…
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CLINICAL_TRIALS trial_result · 2023-04-04Clinical Trial Update: HCV Related Hepatocellular Carcinoma Recurrence After Directly Acting Antivirals: A Randomized Controlled Trial [Phase 4]
Phase 4 randomized trial evaluating recurrence after direct-acting antivirals in hepatitis C-related hepatocellular carcinoma; study complet…
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CLINICAL_TRIALS trial_result · 2023-03-31Clinical Trial Update: Toripalimab or Placebo as Adjuvant Therapy in Hepatocellular Carcinoma After Radical Resection [Phase 2, Phase 3]
Clinical trial update for toripalimab as adjuvant therapy after radical resection in hepatocellular carcinoma is in Phase 2 and Phase 3; sta…
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Lenvatinib Combined Toripalimab in Advanced Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial investigating lenvatinib plus toripalimab in advanced hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Lenvatinib in Combination With Camrelizumab as First-Line Therapy in Patients With Advanced HCC [Phase 1, Phase 2]
A first-line trial evaluating lenvatinib in combination with camrelizumab for advanced hepatocellular carcinoma is in Phase 1/2 with status …
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Regorafenib Combined With PD-1 Inhibitor Therapy for Second-line Treatment of Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating regorafenib in combination with a PD-1 inhibitor for second-line hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Effects of Esketamine on Acute Abdominal Pain After TACE in Patients With Hepatocellular Carcinoma [Phase 4]
Phase 4 clinical trial examining the effects of esketamine on acute abdominal pain after transarterial chemoembolization in hepatocellular c…
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CLINICAL_TRIALS trial_result · 2023-03-22Clinical Trial Update: Ablation Plus Tislelizumab Versus Ablation Alone for Intrahepatic Recurrent Early Stage HCC [Phase 2]
Phase 2 trial updating ablation plus tislelizumab versus ablation alone for intrahepatic recurrent early-stage hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2023-03-21Clinical Trial Update: Study of Pembrolizumab (MK-3475) or Placebo Given With Best Supportive Care in Asian Participants With Previously Treated Advanced Hepatocellular Carcinoma (MK-3475-394/KEYNOTE-394) [Phase 3]
Phase 3 study MK-3475-394/KEYNOTE-394 evaluated pembrolizumab versus placebo with best supportive care in Asian patients with previously tre…
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CLINICAL_TRIALS trial_result · 2023-03-21Clinical Trial Update: Sintilimab Combined With Bevacizumab and Liver Protective Support Therapy in Unresectable Hepatocellular Carcinoma [Phase 2]
Phase 2 trial investigating sintilimab plus bevacizumab and liver protective support therapy for unresectable hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2023-03-16Clinical Trial Update: Safety and Efficacy Study of Radioembolization in Combination With Durvalumab in Locally Advanced and Unresectable HCC [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating radioembolization combined with durvalumab for locally advanced, unresectable hepatocellular carcinoma…
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CLINICAL_TRIALS trial_result · 2023-03-13Clinical Trial Update: Applicability of PDOX in Patients With Primary Liver Cancer: A Randomized Controlled Trial [Phase 3]
Phase 3 randomized trial evaluating applicability of PDOX in patients with resectable hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2023-03-10Clinical Trial Update: the Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma [Phase 2, Phase 3]
A trial update for Rulonilimab in combination with Lenvatinib in hepatocellular carcinoma is in Phase 2 and Phase 3 and currently recruiting…
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: The Synergistic Effect of Portal Venous Supply Control and Immunotherapy in Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating the combination of portal venous supply control with immunotherapy for hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: Candonilimab Plus Bevacizumab for Patients With Advanced HCC Who Progressed on A+T [Phase 2]
Phase 2 clinical trial update evaluating Candonilimab plus Bevacizumab for advanced hepatocellular carcinoma patients who progressed on A+T …
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: Immunological Variables Associated to ICI Toxicity in Cancer Patients [Phase 2]
A Phase 2 clinical trial investigating immunological variables associated with immune checkpoint inhibitor toxicity in cancer patients.
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CLINICAL_TRIALS trial_result · 2023-03-03Clinical Trial Update: A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors [Phase 1, Phase 2]
A Phase I/II study investigating regorafenib in combination with avelumab in various solid tumors, spanning Phase 1 and Phase 2 cohorts.
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CLINICAL_TRIALS trial_result · 2023-03-03Clinical Trial Update: A Study of Apatinib in Patients With Advanced Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial of apatinib in patients with advanced hepatocellular carcinoma has been completed.