Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: TACE Combined With Immune Checkpoint Inhibitors for Liver Malignant Tumors [NA]
This clinical trial assesses the combination of transarterial chemoembolization (TACE) with immune checkpoint inhibitors for non-resectable …
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Lenvatinib After Progression on Atezolizumab-bevacizumab in Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial evaluating lenvatinib after progression on atezolizumab-bevacizumab for hepatocellular carcinoma is currently active …
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Prediction and Prognostic Analysis of Liver Abscess Formation After Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma (CHANCE 2407)
A CHANCE 2407 trial investigates prediction and prognosis of liver abscess formation after transarterial chemoembolization in hepatocellular…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Bevacizumab in Combination With Sintilimab Versus Transcatheter Arterial Chemoembolization for the Treatment of Intermediate Stage Hepatocellular Carcinoma (Beyond Up-To-Seven Criteria) [Phase 2]
This entry describes a Phase 2 randomized trial evaluating bevacizumab plus sintilimab versus transarterial chemoembolization for intermedia…
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: HAIC Combined With Adebrelimab Plus Apatinib as the First-line Treatment for HCC in BCLC Stage C: An Open-label, Single-arm, Phase II Study [Phase 2]
This is a Phase II open-label, single-arm trial evaluating hepatic arterial infusion chemotherapy (HAIC) combined with adebrelimab and apati…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Checkpoint Inhibitor Combinations Therapy as First Line for HCC Via IT [Phase 2]
A Phase 2 clinical trial is evaluating first-line checkpoint inhibitor combination therapy for hepatocellular carcinoma and is currently rec…
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Backline Treatment of Advanced Hepatocellular Carcinoma With Palbociclib [NA]
A clinical trial is evaluating palbociclib as a backline treatment for advanced hepatocellular carcinoma and is currently recruiting.
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CLINICAL_TRIALS other · 2024-06-26Clinical Trial Update: Infusion of PD1/PDL1/CTLA4 Inhibitors Via Hepatic Arterial for Immunotherapy of Hepatocellular Carcinoma [Phase 3]
Phase 3 clinical trial investigating infusion of PD-1/PD-L1/CTLA-4 inhibitors via hepatic artery for hepatocellular carcinoma; currently rec…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Intratumor CpG-ODN Injection Boosters Immune Killing Against in Situ Tumor Antigen Release for Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating intratumoral CpG-ODN injections to boost immune killing and in situ tumor antigen release in advanced soli…
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: HAIC Combined With TQB2450 and Anlotinib in Second-line Treatment of Advanced Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating hepatic arterial infusion chemotherapy (HAIC) combined with TQB2450 and Anlotinib for second-line treatment of adva…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: TACE, Sorafenib and PD-1 Monoclonal Antibody in the Treatment of HCC [Phase 2]
Phase 2 trial evaluating the combination of transarterial chemoembolization (TACE), sorafenib, and a PD-1 monoclonal antibody for hepatocell…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression [Phase 1]
Phase 1 trial evaluating GPC3-CAR-T cell therapy for glypican-3 expressing cancers. The study includes hepatocellular carcinoma and squamous…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating engineered tumor-infiltrating lymphocytes (TILs) and CAR-TILs for advanced solid tumors, sponsored by the …
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors [Phase 2, Phase 3]
Clinical trial update for a Phase 2/Phase 3 study examining trans-arterial/intra-tumor infusion of checkpoint inhibitors plus chemotherapy f…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Non-contrast Abbreviated MRI for Secondary Surveillance of HCC
A completed clinical trial evaluating non-contrast abbreviated MRI for secondary surveillance of hepatocellular carcinoma. The study is spon…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors [Phase 2]
This Phase 2 clinical trial is evaluating a three-drug combination (trametinib, everolimus, and lenvatinib) for recurrent/refractory advance…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: Palliative Hepatectomy Combined With Targeted Therapy and Immunotherapy for Advanced Hepatocellular Carcinoma [Phase 1]
An ongoing Phase 1 clinical trial is evaluating palliative hepatectomy combined with targeted therapy and immunotherapy for hepatocellular c…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Efficacy and Safety of HAIC in Combination With TQB2868 and Ramucirumab for Second-line Treatment of Advanced Hepatocellular Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of combining hepatic arterial infusion chemotherapy (HAIC) with TQB2868 and ramu…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy [NA]
This completed University of Maryland study evaluated whether postoperative heme oxygenase induction and carbon monoxide production can asse…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Study of SHR-8068 Combined With Adebrelimab and Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating SHR-8068 combined with Adebrelimab and Bevacizumab for advanced hepatocellular carcinoma is currently re…
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: A Study of Lenvatinib Plus Nivolumab in Participants With Hepatocellular Carcinoma [Phase 1]
Phase 1 study of lenvatinib plus nivolumab in hepatocellular carcinoma has completed and results have been posted.
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Cohort of Patients With Hepatocellular Carcinoma or Cholangiocarcinoma
A clinical trial is enrolling a cohort of patients with hepatocellular carcinoma or cholangiocarcinoma.
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CLINICAL_TRIALS trial_result · 2024-06-17Clinical Trial Update: RFA Versus SBRT for Recurrent Small HCC [Phase 3]
A Phase 3 trial comparing radiofrequency ablation (RFA) versus stereotactic body radiotherapy (SBRT) for recurrent small hepatocellular carc…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Precision Treatment of Unresectable HCC Guided by Multi-omics Deep Learning Models [Phase 1]
A Phase 1 trial for unresectable hepatocellular carcinoma using multi-omics deep learning to guide precision therapy and is currently recrui…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Intra-Tumoral Vascular Growth Patterns is a Robust Indicator of Adjuvant Therapy Following Liver Resection in HCC
The trial explores intra-tumoral vascular growth patterns as a potential indicator to guide adjuvant therapy following liver resection for h…