Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Sorafenib Chemoembolization Evaluation Controlled Trial [Phase 3]
A Phase 3 trial evaluating sorafenib in combination with hepatic chemoembolization for hepatocellular carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Stereotactic Body Radiation Therapy (SBRT) vs Trans-Arterial Chemoembolization (TACE) as Bridge to Transplant [Phase 3]
Phase 3 trial comparing stereotactic body radiation therapy (SBRT) to trans-arterial chemoembolization (TACE) as a bridge to liver transplan…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies. [NA]
A multicenter Phase II basket trial at Zhejiang Cancer Hospital is evaluating hypofractionated radiotherapy or SBRT followed by immunotherap…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: Concurrently vs Sequentially Combined HAIC With Targeted and Immunotherapy in Potentially Resectable HCC [Phase 3]
A Phase 3 clinical trial registry entry examining concurrent versus sequential hepatic arterial infusion chemotherapy combined with targeted…
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Perioperative Risk of Immunotherapy Based Neoadjuvant and Conversion Therapy for Hepatocellular Carcinoma
This clinical trial assesses perioperative risks associated with immunotherapy-based neoadjuvant and conversion therapy for hepatocellular c…
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CLINICAL_TRIALS withdrawal · 2024-08-26Clinical Trial Update: A Study Evaluating Atezolizumab and Bevacizumab Plus ADI-PEG 20 in Patients With Locally Advanced / Metastatic Hepatocellular Carcinoma [Phase 1, Phase 2]
A Phase 1/2 study evaluating atezolizumab, bevacizumab, and ADI-PEG 20 for locally advanced or metastatic hepatocellular carcinoma has been …
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Gut Microbiota in Liver Cancer (Treated With TKIs In Combination With ICIs) [Phase 2]
A Phase 2 study evaluating how gut microbiota might affect outcomes in liver cancer patients treated with a combination of tyrosine kinase i…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Intra-tumor Injection of Drug-eluting Microspheres With Multiple Drugs [Phase 2]
Phase 2 clinical trial update for intra-tumor injection of drug-eluting microspheres delivering multiple drugs in hepatocellular carcinoma; …
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Single Arm Clinical Trial (Gut Microbiota and HCC) [Phase 2]
Phase 2 single-arm clinical trial investigating the relationship between gut microbiota and hepatocellular carcinoma. The study status is no…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Study of ThermoDox With Standardized Radiofrequency Ablation (RFA) for Treatment of Hepatocellular Carcinoma (HCC) [Phase 3]
A Phase 3 trial evaluating ThermoDox in combination with standardized radiofrequency ablation for hepatocellular carcinoma has completed and…
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CLINICAL_TRIALS research · 2024-08-20Clinical Trial Update: Triple Therapy Sequential Radiotherapy in Unresectable HCC (TALENP003)
ClinicalTrials.gov entry TALENP003 describes a trial of triple therapy sequential radiotherapy for unresectable hepatocellular carcinoma, cu…
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CLINICAL_TRIALS trial_result · 2024-08-19Clinical Trial Update: The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy (#HOPE4LIVER EU/UK) [NA]
This clinical trial update reports on the HistoSonics System using histotripsy for treating liver tumors, including hepatocellular carcinoma…
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: CT011 Autologous CAR-T Cells in Patients With Hepatocellular Carcinoma at Risk of Recurrence After Surgical Resection [Phase 1]
Phase 1 clinical trial evaluating CT011 autologous CAR-T cells for hepatocellular carcinoma in patients at risk of recurrence after surgical…
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Application of Perioperative Remote Ischemic Conditioning in Patients Undergoing Hepatectomy [NA]
This document reports a completed clinical trial evaluating perioperative remote ischemic conditioning in patients undergoing hepatectomy fo…
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Image Driven Hepatocellular Carcinoma Invasiveness Evaluation Research
This document provides a clinical trial update for an image-driven study evaluating invasiveness in hepatocellular carcinoma (stage III). Th…
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CLINICAL_TRIALS research · 2024-08-16Clinical Trial Update: a Cohort Study (Gut Microbiota and HCC)
A cohort study examining the relationship between gut microbiota and hepatocellular carcinoma is in planning and not yet recruiting. Sponsor…
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FDA approval · 2024-08-14FDA Approved: EOVIST — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
FDA approved a supplemental application for EOVIST (gadoxetate disodium) by Bayer, updating the product labeling. The change involves expans…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: A Single Center Study of Donafenib Combined With PD-1 + TACE in the First-line Treatment of aHCC [Phase 2]
This is a Phase 2, single-center study evaluating donafenib in combination with a PD-1 inhibitor and transarterial chemoembolization as firs…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: Comprehensive Prognostic Model: The Study Introduces a Novel Prognostic Model That Incorporates a Wide Range of Clinical and Laboratory Variables, Providing a More Holistic Approach to Predicting Overall Survival in HCC Patients
A clinical trial update presents a novel prognostic model that integrates diverse clinical and laboratory variables to predict overall survi…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: Ablation of Oligometastasis Combined With Lenvatinib and PD-1 Inhibitor for Advanced Hepatocellular Carcinoma [NA]
Clinical trial assessing the combination of ablation of oligometastasis, lenvatinib, and a PD-1 inhibitor for advanced hepatocellular carcin…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: Safety and Efficacy of Autologous Tumor-infiltrating Lymphocytes Therapy in Patients With Hepatocellular Carcinoma [Phase 1, Phase 2]
This entry notes a phase 1/2 clinical trial evaluating autologous tumor-infiltrating lymphocytes therapy for hepatocellular carcinoma, curre…
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CLINICAL_TRIALS research · 2024-08-12Clinical Trial Update: Find HDV and Determine Its Status in Turkey
A Turkish clinical trial is currently recruiting to Find HDV and determine its status, focusing on hepatitis D infection and related liver c…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: An Open-Label, Multiple-Center, Phase IIa/IIb Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of VG161 as Monotherapy and in Combination With Nivolumab for Treatment of Patients With Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma [Phase 2]
Open-label Phase IIa/IIb trial evaluating VG161 as monotherapy and in combination with nivolumab for hepatocellular carcinoma or intrahepati…
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CLINICAL_TRIALS withdrawal · 2024-08-09Clinical Trial Update: Pre-Transplant INCBB099280 for Hepatocellular Carcinoma (HCC) [Phase 1]
A Phase 1 trial evaluating INCBB099280 as a pre-transplant therapy for hepatocellular carcinoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: GPC3-targeting CART Cell in Treatment of Advanced Hepatocellular Carcinoma [Phase 1]
Phase 1 trial evaluating a GPC3-targeting CART cell therapy in advanced hepatocellular carcinoma has been terminated.