Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS other · 2024-12-03Clinical Trial Update: HAIC Combined with PD-1 Inhibitor in Potentially Resectable Locally Advanced HCC [Phase 2]
Phase 2 clinical trial evaluating hepatic arterial infusion chemotherapy (HAIC) combined with a PD-1 inhibitor for potentially resectable lo…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Ablation of Pulmonary Oligometastasis Combined With System for Advanced Hepatocellular Carcinoma
This clinical trial is evaluating ablation of pulmonary oligometastasis combined with systemic therapy in patients with advanced hepatocellu…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: Spanish Registry of Digestive Tumours RETUD
This entry notes the RETUD Spanish registry for digestive tumours is currently recruiting, sponsored by the Spanish Cooperative Group for th…
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: Safety and Effectiveness of Eye90 Microspheres™ in the Treatment of Unresectable Hepatocellular Carcinoma (HCC) and Metastatic Colorectal Cancer (mCRC) [NA]
A completed clinical trial evaluating Eye90 Microspheres for unresectable hepatocellular carcinoma and metastatic colorectal cancer, reporti…
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CLINICAL_TRIALS research · 2024-11-29Clinical Trial Update: Downstaging Protocol Containing Immunotherapy for HCC Beyond the Milan Criteria Before Liver Transplantation [Phase 2]
A Phase 2 clinical trial evaluating a downstaging protocol that includes immunotherapy for hepatocellular carcinoma patients beyond Milan cr…
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CLINICAL_TRIALS research · 2024-11-29Clinical Trial Update: Efficacy and Safety of ALSS Treatment for ICIs-LF in Patients With HCC [NA]
A clinical trial is currently recruiting to evaluate the efficacy and safety of artificial liver support system (ALSS) for immune-mediated l…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry)
An observational registry study (SIRtain Registry) evaluating the use of SIR-Spheres Y-90 resin microspheres for unresectable liver tumors. …
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Combination of SFRT, PD-L1 Inhibitor, and Anti-VEGF in Advanced Hepatocellular Carcinoma [NA]
This study evaluates a combination of spatially fractionated radiotherapy, a PD-1 inhibitor, and anti-VEGF therapy for advanced hepatocellul…
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FDA approval · 2024-11-26FDA Approved: SORAFENIB — Supplemental Application (Dr.Reddys Laboratories Inc)
FDA approved a supplemental application for sorafenib submitted by Dr. Reddy's Laboratories Inc. This action provides supplemental approval …
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: A Study of Nivolumab and Ipilimumab and Nivolumab Alone in Combination With Trans-arterial ChemoEmbolization (TACE) in Participants With Intermediate Stage Liver Cancer [Phase 3]
Phase 3 trial evaluating nivolumab with or without ipilimumab in combination with trans-arterial chemoembolization for intermediate-stage he…
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CLINICAL_TRIALS research · 2024-11-26Clinical Trial Update: Comparison of Serum Myokine Dosages and Imaging Methods in the Evaluation of Sarcopenia in Patients With Hepatocellular Carcinoma [NA]
A clinical trial evaluating serum myokine dosages and imaging methods to evaluate sarcopenia in patients with hepatocellular carcinoma, whic…
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CLINICAL_TRIALS withdrawal · 2024-11-25Clinical Trial Update: Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs
A Travera Inc clinical trial (NCT04985357) evaluating mass response as a biomarker for tumor sensitivity to drugs has been withdrawn; no res…
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CLINICAL_TRIALS withdrawal · 2024-11-25Clinical Trial Update: A Social Support Intervention to Improve Treatment Among Hispanic Kidney and Liver Cancer Patients in Arizona [NA]
This clinical trial evaluating a social support intervention for Hispanic patients with renal cell carcinoma or hepatocellular carcinoma in …
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08) [Phase 1, Phase 2]
GI Innovation's GI-102 is being studied in a phase 1/2 trial as a single agent and in combination with pembrolizumab or trastuzumab deruxtec…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Clinical Study of SN301A Injection in the Treatment of Hepatocellular Carcinoma [EARLY_Phase 1]
This document reports an ongoing EARLY Phase 1 clinical trial evaluating SN301A Injection for hepatocellular carcinoma, sponsored by Shangha…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating the safety of combining navitoclax with sorafenib tosylate in patients with relapsed or refractory solid tumors, in…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: The Diagnostic Efficacy and Lesion Detection Advantages of 18F-FDG PET/CT and Enhanced MRI in Hepatic Malignancies
This clinical trial update assesses the diagnostic performance of 18F-FDG PET/CT and enhanced MRI for detecting hepatic tumors, including he…
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CLINICAL_TRIALS withdrawal · 2024-11-22Clinical Trial Update: TATE Versus TACE in Intermediate Stage HCC [Phase 2]
A Phase 2 trial comparing TATE to transarterial chemoembolization in intermediate-stage hepatocellular carcinoma has been terminated.
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant [Phase 2]
A Phase 2 clinical trial evaluating the combination of durvalumab and tremelimumab for hepatocellular carcinoma in patients listed for liver…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: A Study of PTX-9908 Injection for Non-resectable HCC with TACE [Phase 1, Phase 2]
PTX-9908 Injection is in a Phase 1/2 study for non-resectable hepatocellular carcinoma in combination with transarterial chemoembolization (…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Construction of a Recurrence Risk Prediction Model for Liver Resection Based on Drug Sensitivity of Patient-derived Hepatocellular Carcinoma Organoid
A clinical trial aims to build a recurrence risk prediction model for hepatocellular carcinoma patients undergoing liver resection, using dr…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Rituximab Combined With Prior Therapy in Advanced Hepatocellular Carcinoma: Efficacy & Safety Study [Phase 2]
A Phase 2 trial evaluating rituximab in combination with prior therapy for advanced hepatocellular carcinoma is currently recruiting to asse…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Ten-Year Outcomes of Operable Solitary Hepatocellular Carcinoma Patients: Impact of Tumor Size Over 6.5 cm and Microvascular Invasion
This clinical trial examines ten-year outcomes for operable solitary hepatocellular carcinoma, evaluating the impact of tumor size over 6.5 …
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: A Randomized, Placebo-controlled, Double-blind Phase 2 Study With OSI-906 in Patients With Advanced HCC [Phase 2]
A randomized, placebo-controlled, double-blind Phase 2 study evaluating OSI-906 in advanced hepatocellular carcinoma has been terminated. Th…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Intravascular Radiofrequency Ablation of Sympathetic Nerves for the Treatment of Hepatocellular Carcinoma [NA]
Recruitment is ongoing for a study evaluating intravascular radiofrequency ablation of sympathetic nerves as a treatment for hepatocellular …