Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Building Evidence for Ablative Internal Radiation Therapy in Localized HCC Beyond the Up-To-7 Criteria [Phase 2]
A Phase 2 clinical trial evaluating ablative internal radiation therapy for localized hepatocellular carcinoma beyond the Up-To-7 criteria i…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma [Phase 2]
Phase 2 trial assessing whether deep multi-omics profiling can predict response, resistance and recurrence to adjuvant atezolizumab plus bev…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Atezolizumab and Bevacizumab as Neoadjuvant Plus Adjuvant Treatment in HCC [Phase 2]
Phase 2 study evaluating the combination of atezolizumab and bevacizumab as neoadjuvant and adjuvant therapy for resectable hepatocellular c…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Iparomlimab and Tuvonralimab as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With High Risk of Recurrence [Phase 2]
Phase 2 clinical trial evaluating neoadjuvant Iparomlimab and Tuvonralimab for resectable hepatocellular carcinoma at high risk of recurrenc…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: International Study of High-Risk Patients for Hepatocellular Carcinoma Using Liquid Biopsy
A Johns Hopkins University–sponsored international trial evaluating liquid biopsy to detect hepatocellular carcinoma in high-risk patients w…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Phase II Study of PRL3-ZUMAB in Advanced Solid Tumors [Phase 2]
Phase II clinical trial of PRL3-ZUMAB in advanced solid tumors is currently recruiting, with planned investigations in gastric cancer and he…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: FOLFOX Combined With Durvalumab (MEDI4736), Bevacizumab, and Stereotactic Body Radiotherapy in Sequential Treatment of Potentially Resectable Locally Advanced Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating sequencing of FOLFOX chemotherapy with Durvalumab (MEDI4736) and Bevacizumab, followed by stereotactic body radioth…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Prospective Cohort of Patients With Hepatocellular Carcinoma in France
A prospective cohort study of patients with hepatocellular carcinoma being recruited in France, sponsored by Centre Hospitalier Universitair…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Chronic Hepatitis B Virus Infection in Zambia
An ongoing clinical trial in Zambia studying chronic hepatitis B virus infection and liver-related conditions (fibrosis, cirrhosis, alcoholi…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Neoadjuvant Therapy of iIparomlimab and Tuvonralimab Combined With Lenvatinib for Hepatocellular Carcinoma [Phase 2]
This Phase 2 clinical trial updates a neoadjuvant combination of iparomlimab, tuvonralimab, and lenvatinib for resectable hepatocellular car…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Liver Fibrosis in Zambian HIV-HBV Co-infected Patients
This ClinicalTrials.gov update concerns a study in Zambian patients co-infected with HIV and hepatitis B, investigating liver fibrosis and r…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Head-to-Head Comparison of Hepatocellular Cancer (HCC) Screening Strategies: A Prospective Population-Based Cohort Study in Zhongshan City
A prospective population-based cohort study in Zhongshan City comparing hepatocellular carcinoma (HCC) screening strategies is currently rec…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Comparison of ultraSound, Abbreviated MRI witH and Without HBP aS mOdalities for HCC suRveillance in patienTs With High Risk [NA]
This clinical trial compares ultrasound and abbreviated MRI (with and without hepatobiliary phase) for hepatocellular carcinoma surveillance…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: A Multicenter, Prospective Study of Perioperative Finotonlimab Combined With Bevacizumab in Resectable Hepatocellular Carcinoma Patients With High-Risk Factors for Recurrence [NA]
A multicenter prospective trial is evaluating perioperative finotonlimab in combination with bevacizumab for patients with resectable hepato…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Photon Radiotherapy Plus Tremelimumab/Durvalumab for BCLC Stage B and C HCC [Phase 2]
A Phase 2 clinical trial is evaluating the combination of photon radiotherapy with tremelimumab and durvalumab for BCLC stage B and C hepato…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: KAT-101 in Subjects With Hepatocellular Carcinoma (HCC) [Phase 1, Phase 2]
A Phase 1/2 trial of KAT-101 for hepatocellular carcinoma and fibrolamellar carcinoma has been suspended.
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO [Phase 3]
A Phase 3 trial is evaluating whether an immune-oncology therapy given every three months after six months of standard administration is as …
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Real-world Study on Liver Cancer Risk in Chronic Hepatitis B Patients With Family History of Liver Cancer
A real-world study to evaluate liver cancer risk in patients with chronic hepatitis B who have a family history of liver cancer, sponsored b…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Seravue Validation Study for Hepatocellular Carcinoma (HCC) Diagnosis
A validation study is planned to evaluate Seravue for diagnosing hepatocellular carcinoma, with recruitment not yet started.
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: ctDNA Monitoring in Patients With HCC and mCRC [NA]
A recruiting clinical trial from the Medical University of Warsaw is evaluating ctDNA monitoring in patients with hepatocellular carcinoma a…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: DYNAmic Immune Microenvironment of HCC Treated With atezolIzumab Plus bevaCizumab [Phase 2]
Phase 2 clinical trial update studying the immune microenvironment in hepatocellular carcinoma treated with atezolizumab plus bevacizumab.
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Abbreviated MRI Using Gadoxetic Acid Versus Ultrasonography for Surveillance of Early-stage HCC in Patients at High Risk [NA]
A clinical trial is evaluating abbreviated MRI using gadoxetic acid versus ultrasonography for surveillance of early-stage hepatocellular ca…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Personalized Tumor Neoantigen mRNA Therapy for Advanced Hepatocellular Carcinoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating a personalized tumor neoantigen mRNA therapy for advanced hepatocellular carcinoma. The study is current…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Study of CT-01 as Monotherapy and Combination Therapy in Subjects With Intermediate or Advanced Hepatocellular Carcinoma [Phase 1]
A Phase 1 clinical trial update for CT-01 in intermediate or advanced hepatocellular carcinoma shows the study is currently NOT_YET_RECRUITI…
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: PD-1 Inhibitor Combined With 125I Seed Implantation for Hepatocellular Carcinoma's Extrahepatic Metastasis: Efficacy and Safety [NA]
A completed clinical trial evaluated a PD-1 inhibitor in combination with 125I seed implantation for hepatocellular carcinoma with extrahepa…