Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Study of ET140203 T Cells in Adults With Advanced Hepatocellular Carcinoma (ARYA-1) [Phase 1]
A Phase 1 trial (ARYA-1) evaluating ET140203 T Cells in adults with advanced hepatocellular carcinoma has been terminated.
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Risk Assessment for HBV-Related Liver Cancer
A recruiting clinical trial studying risk assessment for HBV-related liver cancer in patients with HBV-related liver cirrhosis.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Predictive Biomarkers in Patients With Advanced Hepatocellular Carcinoma Treated With Systemic Therapy
This clinical trial update discusses predictive biomarkers in adults with advanced hepatocellular carcinoma treated with systemic therapy; t…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: AI Multitask Model for HCC Treatment
A clinical trial evaluating an AI multitask model for hepatocellular carcinoma treatment has completed.
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: EGCG for Hepatocellular Carcinoma Chemoprevention [Phase 2]
A Phase 2 clinical trial is evaluating epigallocatechin gallate (EGCG) for chemoprevention of hepatocellular carcinoma in patients with cirr…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Study on the Heterogeneity of Efficacy of Interventional Therapy Combined With Systemic Therapy for Liver Cancer Based on Multi-center Real-world Data
This clinical trial update outlines a multi-center real-world study evaluating heterogeneity in efficacy of interventional therapy combined …
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Gecacitinib Combined With Donafenib and PD-1 Inhibitor as Immune Rechallenge Therapy for Unresectable Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial evaluating a triple combination of gecacitinib, donafenib, and a PD-1 inhibitor as an immune rechallenge therapy for …
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer [Phase 2]
A Phase 2 trial evaluating the combination of sorafenib with hydroxychloroquine for hepatocellular carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Regorafenib and Durvalumab for the Treatment of High-Risk Liver Cancer [Phase 2]
A Phase 2 study evaluating the combination of regorafenib and durvalumab for high-risk hepatocellular carcinoma is currently active but not …
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Apatinib Mesylate and Camrelizumab Combined With TACE as Neoadjuvant Therapy for Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating apatinib mesylate plus camrelizumab with transarterial chemoembolization as neoadjuvant therapy for hepatocellular …
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: A Study of TPST-1120 With Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic HCC Not Previously Treated With Systemic Therapy [Phase 3]
Phase 3 trial evaluating TPST-1120 in combination with atezolizumab and bevacizumab for unresectable or metastatic hepatocellular carcinoma …
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: A Clinical Study of Multi-target Hi-TCR-T Cells in the Treatment of Advanced Hepatocellular Carcinoma [Phase 1, Phase 2]
This entry reports an ongoing Phase 1/2 clinical trial evaluating multi-target Hi-TCR-T cell therapy for advanced hepatocellular carcinoma, …
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Unravelling the Impact of Radiofrecuency in Liver Surgery: the Key to Decrease Local Recurrence? [NA]
A clinical trial from Hospital del Mar is investigating the impact of radiofrequency in liver surgery on reducing local recurrence in liver …
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: AI-Based Prediction of HCC Recurrence Patterns After Resection (APAR)
A clinical trial at Tongji Hospital is evaluating an AI-based model to predict recurrence patterns of hepatocellular carcinoma after liver r…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 trial of SON-DP in participants with relapsed/refractory solid tumors intolerant to standard therapies, including gastric cancer and…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Cabozantinib for Progressive HCC Post-first-line Immuno-oncologic Combination Therapy [Phase 2]
Phase 2 trial of cabozantinib for hepatocellular carcinoma progressing after first-line immuno-oncology therapy; study status is not yet rec…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: A Pilot Study to Evaluate the Safety of a 3 Weeks Sitagliptin Treatment in HCC Patients Undergoing Liver Resection [Phase 1]
A Phase 1 pilot study assessing the safety of a 3-week sitagliptin treatment in patients with hepatocellular carcinoma undergoing liver rese…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: SIRT With Tremelimumab and Durvalumab for Resectable HCC [Phase 1]
Phase 1 clinical trial evaluating the combination of selective internal radiation therapy (SIRT) with tremelimumab and durvalumab for resect…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: A Phase II Single-Arm Study of Iparomlimab and Tuvonralimab (QL1706) in Combination With Lenvatinib and TACE for Advanced Hepatocellular Carcinoma [Phase 2]
Phase II single-arm study of Iparomlimab and Tuvonralimab (QL1706) in combination with lenvatinib and transarterial chemoembolization for ad…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: The Treatment of Liver Injury After Liver Resection With Polyene Phosphatidylcholine [Phase 4]
A Phase 4 clinical trial is evaluating polyene phosphatidylcholine for liver injury after liver resection; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: The Safety and Efficacy of Transarterial Chemoembolization (TACE) + Lenvatinib + Programmed Cell Death Protein 1 (PD-1) Antibody of Advanced Unresectable Hepatocellular Carcinoma [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and efficacy of transarterial chemoembolization combined with lenvatinib and a PD-1 antibody in advanced un…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: The Role of Serum AKR1B10 in Early Warning of Hepatocellular Carcinoma in Cirrhosis Patients
A clinical trial is evaluating whether serum AKR1B10 can serve as an early biomarker to warn of hepatocellular carcinoma in patients with ci…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Efficacy and Safety of Multimodal Ablation Combined With PD-1 Monoclonal Antibody, Lenvatinib and TACE in the Treatment of Unresectable Primary Hepatocellular Carcinoma: A Single-Arm, Single-Center Clinical Study [NA]
This is a single-arm, single-center clinical study evaluating multimodal ablation in combination with a PD-1 monoclonal antibody, lenvatinib…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Psychoeducational Intervention for Patients With Hepatocellular Carcinoma [NA]
This ClinicalTrials.gov update reports an ongoing trial at Massachusetts General Hospital evaluating a psychoeducational intervention for he…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Lparomlimab and Tuvonralimab Injection in Combination With TACE and Lenvatinib in the Treatment of Second-Line Therapy for Unresectable Intermediate-to-Advanced Hepatocellular Carcinoma [Phase 2]
A Phase 2 trial evaluating Lparomlimab and Tuvonralimab in combination with TACE and lenvatinib as second-line therapy for unresectable inte…