Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Neoadjuvant Atezo, Adjuvant Atezo + Beva Combined With RF Ablation of Small HCC: a Multicenter Randomized Phase II Trial [Phase 2]
A multicenter randomized Phase II trial is evaluating neoadjuvant atezolizumab and adjuvant atezolizumab plus bevacizumab with radiofrequenc…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer [Phase 2, Phase 3]
A prospective Phase 2/Phase 3 clinical trial evaluating memantine in patients with cirrhosis and hepatocellular carcinoma is currently recru…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Adjuvant IP-001 Treatment for HCC Patients Following Surgical Resection and Ablation or Ablation Alone [Phase 2]
Phase 2 clinical trial investigating adjuvant IP-001 following surgical resection and ablation (or ablation alone) for hepatocellular carcin…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Brazilian Reality of Hepatocellular Carcinoma
AstraZeneca-sponsored hepatocellular carcinoma trial conducted in Brazil has completed, with analyses by BCLC stage.
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Neoadjuvant HAIC and PD-1 Plus Adjuvant PD-1 for High-risk Recurrent HCC [Phase 2]
Clinical trial update for a Phase 2 neoadjuvant hepatic arterial infusion chemotherapy with PD-1 inhibitor and adjuvant PD-1 in high-risk re…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Neoadjuvant IMRT Combined With Camrelizumab and Apatinib for Resectable HCC With PVTT [Phase 2]
A Phase 2 neoadjuvant trial is evaluating camrelizumab plus apatinib with intensity-modulated radiotherapy for resectable hepatocellular car…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Phase I Clinical Trial of CT0180 Cells in the Treatment of Hepatocellular Carcinoma [Phase 1]
Phase I trial update for CT0180 cells in advanced hepatocellular carcinoma; the study is active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis
Clinical trial evaluating the utility of [68Ga]Ga-PSMA-11 PET/MRI for assessing liver cirrhosis and related conditions is currently recruiti…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Systemic Chemotherapy With FOLFOX Plus Atezolizumab & Bevacizumab for Patients With Advanced HCC Who Previously Received Atezolizumab & Bevacizumab [Phase 2]
Phase 2 trial evaluating FOLFOX chemotherapy with atezolizumab and bevacizumab in patients with advanced hepatocellular carcinoma who previo…
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CLINICAL_TRIALS other · 2025-09-25Clinical Trial Update: Adebrelimab + Apatinib in Advanced HCC Post-Systemic Therapy [Phase 2]
A Phase 2 study of Adebrelimab in combination with Apatinib for advanced hepatocellular carcinoma after prior systemic therapy is not yet re…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Real-world Elecsys® GAAD Implementation and Validation to Improve Surveillance and Early Detection of HCC [NA]
This clinical trial update describes the real-world implementation and validation of the Elecsys GAAD assay to improve surveillance and earl…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: LOcoregional vs Systemic Therapy in Patients With BCLC Stage B HCC [Phase 2]
A Phase 2 trial comparing locoregional therapy versus systemic therapy for intermediate-stage hepatocellular carcinoma (BCLC stage B) has be…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Phase I Study of RNA Oligonucleotide, MTL-CEBPA, Atezolizumab and Bevacizumab in Patients With Advanced Hepatocellular Carcinoma. [Phase 1]
Phase I trial evaluating the RNA oligonucleotide MTL-CEBPA in combination with atezolizumab and bevacizumab for advanced hepatocellular carc…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Single-arm Clinical Trial of TACE in Combination With Icaritin as Adjuvant Therapy After Surgery in Patients With Hepatocellular Carcinoma at High Risk of Recurrence [Phase 2, Phase 3]
A single-arm Phase 2/3 clinical trial in hepatocellular carcinoma evaluating adjuvant therapy with Icaritin in combination with transarteria…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Safety and Efficacy of Atorvastatin v. Placebo on HCC Risk [Phase 2]
Phase 2 clinical trial evaluating whether atorvastatin reduces hepatocellular carcinoma risk compared with placebo in patients with liver fi…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC [Phase 2]
Phase 2 clinical trial evaluating a neoantigen dendritic cell vaccine in combination with nivolumab for hepatocellular carcinoma and colorec…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: 68Ga-PSMA-11 PET-directed Radioligand Therapy in Metastatic Hepatocellular Carcinoma (HCC) [Phase 2]
This clinical trial update concerns a Phase 2 study evaluating 68Ga-PSMA-11 PET-directed radioligand therapy in metastatic hepatocellular ca…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista [Phase 3]
Phase 3 study evaluating the safety and efficacy of atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma not previously tr…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Adjuvant Radiotherapy of Sintilimab Versus TACE for HCC [Phase 3]
Phase 3 clinical trial evaluating adjuvant radiotherapy with sintilimab versus transarterial chemoembolization for hepatocellular carcinoma …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: EDN Combined With TACE/HAIC and Second-Line Immune-Targeted Treatment Versus TACE/HAIC Alone in Locally Advanced HCC With Portal Vein Tumor Thrombosis After First-Line Therapy Failure: A Prospective, Multicenter, Randomized Controlled Trial [Phase 1, Phase 2]
A multicenter, randomized Phase 1/2 trial evaluating EDN in combination with TACE/HAIC and a second-line immune-targeted therapy versus TACE…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: EchoTip AcuCore Post-Market Clinical Study
Completed post-market clinical study update for the EchoTip AcuCore device, detailing the completion of the post-market evaluation.
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Immunogenomic Dynamics and Biomarkers in Patients With Hepatocellular Carcinoma Receiving Immunotherapy
Clinical trial update exploring immunogenomic dynamics and biomarkers in hepatocellular carcinoma patients receiving immunotherapy. The stud…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Abbreviated Magnetic Resonance Imaging vs Ultrasound Surveillance for Liver Cancer dETection in People at High Risk of Developing Liver Cancer
A clinical trial update indicates recruitment is ongoing for a study comparing abbreviated MRI to ultrasound surveillance for detecting live…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors, Hepatocellular Carcinoma (HCC), Melanoma, and Pediatric Cancer [Phase 1]
Chiome Bioscience's CBA-1205, an anti-DLK1 monoclonal antibody, is in a Phase I first-in-human trial for advanced solid tumors including hep…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: JS014 Combined With Toripalimab and TACE in Unresectable HCC: a Phase Ib Study [Phase 1]
Phase Ib study evaluating JS014 in combination with toripalimab and transarterial chemoembolization (TACE) for unresectable hepatocellular c…