Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Sequential Transarterial Chemoembolization (TACE), Stereotactic Body Radiation Therapy (SBRT), and Immune Checkpoint Inhibitors for Unresectable Hepatocellular Carcinoma Treated With Donafenib [Phase 2]
A Phase 2 clinical trial in China is testing sequential transarterial chemoembolization (TACE), stereotactic body radiation therapy (SBRT), …
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors [Phase 2]
Phase 2 study evaluating SOT101 in combination with pembrolizumab in selected advanced solid tumors was terminated; results have been posted…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Sequential TACE-SBRT Combined With Targeted Immunotherapy for Patients With Intermediate to Advanced Liver Cancer
A clinical trial evaluating sequential transarterial chemoembolization (TACE) and stereotactic body radiotherapy (SBRT) in combination with …
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Streamlined Resin Y90 Radiation Segmentectomy for Small HCC
Clinical trial update describing a streamlined yttrium-90 resin microsphere radiation segmentectomy approach for small hepatocellular carcin…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Fibroscan Study in HCC [NA]
The document provides an update on a Fibroscan study in hepatocellular carcinoma, including patients scheduled for transarterial chemoemboli…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer [Phase 1, Phase 2]
This document details an ongoing Phase 1/2 clinical trial evaluating cobolimab in combination with dostarlimab in pediatric and young adult …
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors [Phase 1]
This is a completed Phase 1 clinical trial update evaluating CHS-388 (formerly SRF388) in patients with advanced solid tumors, including cle…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy [Phase 2]
Phase 2 trial comparing short-stitch versus traditional suture to prevent incisional hernia after open hepatectomy (liver resection); curren…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Maintenance Zanzalintinib and Durvalumab in Participants With Advanced Hepatocellular Cancer [Phase 2]
Phase 2 trial update evaluating maintenance zanzalintinib plus durvalumab in advanced hepatocellular carcinoma; the study is currently not r…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA) [Phase 2]
Phase 2 trial ZENOBIA evaluating Zanzalintinib in combination with Durvalumab and Tremelimumab for unresectable hepatocellular carcinoma is …
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors [Phase 1]
Phase 1 trial evaluating cytokine-armored GPC3-targeted CAR-T cells in adults with solid tumors, including hepatocellular carcinoma; the stu…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells [Phase 1]
Phase 1 clinical trial evaluating GPC3-targeted CAR T cells armored with IL-15 and IL-21 for GPC3-positive solid tumors; currently recruitin…
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: 68Ga-PSMA-Dual-Contrast PET/MRI or PET/CT for Early Detection of Liver Cancer [Phase 2]
Phase 2 trial assessing 68Ga-PSMA dual-contrast PET imaging for early detection of hepatocellular carcinoma; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: A Phase II Study of Intra-arterial Chemotherapy With Cisplatin and Mitomycin-C in Patients With Hepatocellular Carcinoma [Phase 2]
A Phase II trial evaluating intra-arterial chemotherapy with cisplatin and mitomycin-C in hepatocellular carcinoma has completed, with resul…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Futibatinib and Pembrolizumab for Treatment of Advanced or Metastatic FGF19 Positive BCLC Stage A, B, or C Liver Cancer [Phase 2]
Phase 2 trial results for futibatinib plus pembrolizumab in advanced hepatocellular carcinoma (BCLC A-C and metastatic) have been completed …
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery [NA]
This trial update reports that the sulfur colloid SPECT/CT liver-function study in patients with hepatocellular carcinoma or intrahepatic ch…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Clinical trial SYNERGY-AI is an AI-based precision oncology matching and registry study sponsored by Massive Bio, currently recruiting acros…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: A Study of E7386 in Combination With Pembrolizumab in Previously Treated Participants With Selected Solid Tumors [Phase 1, Phase 2]
Results from a Phase 1/2 study of E7386 in combination with pembrolizumab in previously treated solid tumors (melanoma, hepatocellular carci…
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: Immunotherapy for Advanced Liver Cancer [Phase 2, Phase 3]
A Phase 2/Phase 3 immunotherapy trial for hepatocellular carcinoma has been suspended.
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: Pressure Enabled Delivery of SD-101 With Checkpoint Blockade for Primary Liver Tumors [Phase 1, Phase 2]
A Phase 1/2 trial evaluating pressure-enabled delivery of SD-101 in combination with checkpoint blockade for primary liver tumors has been t…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of HFB301001 in Adult Patients With Advanced Solid Tumors [Phase 1]
The Phase 1 trial of HFB301001 in adults with advanced solid tumors has been terminated.
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Visugromab, Nivolumab and a Tyrosine Kinase Inhibitor (TKI) Compared to Double Placebo and a TKI in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure [Phase 2]
A Phase 2 clinical trial evaluating Visugromab, Nivolumab, and a Tyrosine Kinase Inhibitor versus double placebo and a TKI in unresectable o…
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies [Phase 1]
Open-label Phase 1 safety and tolerability study of INCB062079 in patients with advanced hepatocellular carcinoma and other malignancies; st…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Therasphere® and Systemic Therapy for Patients With Hepatocellular Carcinoma That is High-risk [Phase 2]
Phase 2 clinical trial evaluating TheraSphere in combination with systemic therapy for high-risk hepatocellular carcinoma is currently suspe…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial of INCB099318 in participants with advanced solid tumors has been terminated. The update reports safety, tolerability…