Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Camrelizumab and Apatinib With or Without FOLFOX Chemotherapy for Advanced HCC [Phase 3]
A Phase 3 clinical trial is investigating camrelizumab and apatinib with or without FOLFOX chemotherapy for advanced hepatocellular carcinom…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: HOPE Against Cancer Recurrence in HCC [Phase 4]
Phase 4 clinical trial update for HOPE Against Cancer Recurrence in hepatocellular carcinoma; the study is currently recruiting under sponso…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Safety and Efficacy of Paclitaxel Liposome Arterial Infusion Combined With Systemic Therapy for Second-Line Treatment of Advanced Liver Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the safety and efficacy of paclitaxel liposome delivered via arterial infusion combined with systemic th…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Clinical Trial of Autologous CD19 CAR-T Cells (CNCT19) Therapy for Advanced Hepatocellular Carcinoma [Phase 1]
A Phase 1 clinical trial evaluating autologous CD19 CAR-T CNCT19 therapy for advanced hepatocellular carcinoma is currently recruiting.
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CLINICAL_TRIALS other · 2025-12-15Clinical Trial Update: Anti-PD-1/PD-L1 Antibodies Plus Anti-VEGF Antibody Treatment in Patients With Advanced-Stage HCC
Clinical trial update describing a study of combining anti-PD-1/PD-L1 antibody therapy with an anti-VEGF antibody in patients with advanced …
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Transarterial Chemoembolization With Low-Dose Bevacizumab Plus Atezolizumab as First-Line Treatment for Unresectable Hepatocellular Carcinoma [NA]
A clinical trial update outlines a planned first-line regimen for unresectable hepatocellular carcinoma using transarterial chemoembolizatio…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Organ-specific Responses to Atezolizumab Plus Bevacizumab in Advanced HCC
The trial evaluated organ-specific responses to the combination of atezolizumab and bevacizumab in advanced hepatocellular carcinoma; result…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors [Phase 3]
Phase 3 trial evaluating the duration of PD-1/PD-L1 inhibitor therapy in advanced solid tumors; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Have Not Received Previous Systemic Anticancer Therapy [Phase 3]
A Phase 3 study comparing cabozantinib in combination with atezolizumab versus sorafenib as first-line therapy for advanced hepatocellular c…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: HAIC vs. TACE Combined With ICIs and TKIs in Intermediate-to-Advanced HCC: A Multicenter Study on Liver Injury and Survival
A completed multicenter study in hepatocellular carcinoma compared hepatic artery infusion chemotherapy (HAIC) to transarterial chemoemboliz…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: A Study of TACE Combined With Camrelizumab Plus Rivoceranib (Apatinib) in Patients With Incurable Hepatocellular Carcinoma [Phase 3]
A Phase 3 trial evaluating TACE combined with camrelizumab and rivoceranib (apatinib) for incurable hepatocellular carcinoma is currently ac…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Intravital Microscopy in Human Solid Tumors [NA]
Mayo Clinic is conducting a clinical trial using intravital microscopy in multiple solid tumors, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma [Phase 3]
Clinical trial update for Nofazinlimab (CS1003) in advanced hepatocellular carcinoma; the Phase 3 study is currently active but not recruiti…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Radiotherapy Combined With QL1706 and Bevacizumab for Unresectable Non-metastatic Hepatocellular Carcinoma [Phase 2]
A Phase 2 trial is evaluating radiotherapy in combination with QL1706 and bevacizumab for unresectable non-metastatic hepatocellular carcino…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: A Prospective Observational Study on Efficacy of TARE for Early Stage HCC
A prospective observational study evaluating the efficacy of transarterial radioembolization (TARE) with Yttrium-90 microspheres for early-s…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma [Phase 1, Phase 2]
Hoffmann-La Roche sponsored a Phase 1/2 trial evaluating neoadjuvant immunotherapy combinations in patients with surgically resectable hepat…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Fecal Microbiota Transplantation to RESCUE Patients With Unresectable Hcc Progressors to First Line Therapy With AtezolizUmaB and Bevacizumab [Phase 2]
A Phase 2 trial is evaluating fecal microbiota transplantation in patients with unresectable hepatocellular carcinoma who progress on first-…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: SBRT Plus Systemic Therapy vs Systemic Therapy Alone in BCLC C Hepatocellular Carcinoma [Phase 2]
This Phase 2 clinical trial evaluates adding SBRT to systemic therapy versus systemic therapy alone for hepatocellular carcinoma with BCLC s…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Mutational Landscape in Hepatocellular Carcinoma
This clinical trial update summarizes the mutational landscape of hepatocellular carcinoma based on genomic profiling from the completed stu…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: A Cell-free tsRNA Signature for Early Detection of Hepatocellular Carcinoma
A clinical trial at City of Hope Medical Center is evaluating a cell-free tsRNA signature as a potential biomarker for early detection of he…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: The Effectiveness and Safety in High-risk Patients Receiving First-line Atezolizumab and Bevacizumab Combined With HAIC for HCC: a Retrospective Study [NA]
A retrospective study evaluating the effectiveness and safety of first-line Atezolizumab plus Bevacizumab combined with HAIC in high-risk he…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Identification of an Immune Single Cell Transcriptomic Profile of Responder and Non-responder Hepatocellular Carcinoma Patients Treated With Immune-checkpoint Inhibitors
A clinical trial is investigating an immune single-cell transcriptomic profile associated with response to immune-checkpoint inhibitors in h…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Phase III Study of Toripalimab（JS001） Combined With Lenvatinib for Advanced HCC [Phase 3]
This entry reports a Phase III trial evaluating toripalimab in combination with lenvatinib for advanced hepatocellular carcinoma, which is c…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: New Diagnostic Criteria in the Evaluation Response to Ablation Treatment of Hepatocellular Carcinoma Nodules
This clinical trial is evaluating new diagnostic criteria for assessing response to ablation therapy in hepatocellular carcinoma nodules.
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Understanding Gene ENvironment Interaction in ALcohol-related Hepatocellular Carcinoma [NA]
Clinical trial update for NCT07272200 investigating gene-environment interactions in alcohol-related hepatocellular carcinoma; recruitment i…