Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: A Study to Compare the Effectiveness and Safety of IBI310 Combined With Sintilimab Versus Sorafenib in the First-line Treatment of Advanced HCC [Phase 3]
A Phase 3 trial comparing IBI310 plus Sintilimab versus Sorafenib as first-line treatment for advanced hepatocellular carcinoma has complete…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients [Phase 1]
Phase 1 trial of Cabotamig (ARB202) in advanced gastrointestinal cancers has completed; no specific efficacy results are provided in the doc…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Alectinib in Combination With Nivolumab in the Treatment of Recurrent or Refractory HCC Patients Guided With Serum RNase1 and Tumor Expression of PD-L1 [Phase 1]
Phase 1 study evaluating alectinib in combination with nivolumab for recurrent or refractory hepatocellular carcinoma, guided by serum RNase…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Individualized Surgical Guidance in HCC-BDTT
Completed clinical trial investigating individualized surgical guidance for hepatocellular carcinoma with bile duct tumor thrombus.
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Selective Internal Radiation Therapy and 188Re-SSS Lipiodol Treatment for Liver Cancer (Lip-Re2) [Phase 2]
Phase 2 trial update evaluating selective internal radiation therapy with 188Re-SSS Lipiodol for unresectable hepatocellular carcinoma. The …
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Pressure-enabled Delivery in Radioembolization (TriNav Study) [NA]
The TriNav study, led by Massachusetts General Hospital, is evaluating pressure-enabled delivery in radioembolization for liver cancers; the…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Prevention of Variceal Rebleeding by EUS-guided vs Conventional Endoscopic Therapy in Hepatocellular Carcinoma Patients [NA]
A clinical trial comparing endoscopic ultrasound-guided therapy with conventional endoscopic therapy to prevent variceal rebleeding in patie…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Trial of Atezolizumab and Bevacizumab With SRF388 or Placebo in Patients With Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating atezolizumab and bevacizumab with SRF388 or placebo in hepatocellular carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Safety and Efficacy of LVD + C-TACE + Tis/Len for Unresectable Right-Liver HCC [NA]
A clinical trial update evaluating the safety and efficacy of LVD + C-TACE + Tis/Len for unresectable hepatocellular carcinoma; the study is…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Phase I Clinical Study To Evaluate Pharmacokinetic Profile, Safety, Efficacy and Immunogenicity Of Ipilimumab Biosimilar HLX13 Vs. YERVOY® (US-Sourced YERVOY®) As A First-Line Treatment For Patients With Unresectable Hepatocellular Carcinoma [Phase 1]
Phase I trial evaluating pharmacokinetics, safety, efficacy and immunogenicity of the ipilimumab biosimilar HLX13 versus YERVOY in first-lin…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Effect of Pregabalin on the Postoperative Analgesia in RFA of Focal Lesions in the Liver [Phase 4]
Phase 4 clinical trial investigating pregabalin for postoperative analgesia during radiofrequency ablation of focal liver lesions in hepatoc…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Stereotaxic Irradiation of Hepatocellular Carcinoma [Phase 2]
This document reports the completion of a Phase 2 clinical trial evaluating stereotaxic irradiation for hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Early Biomarkers of Tumor Response in High Dose Hypofractionated Radiotherapy Word Package 3 : Immune Response [NA]
A terminated clinical trial (NCT02439008) investigating early biomarkers of tumor response to high-dose hypofractionated radiotherapy across…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Safety and Efficacy of Atezolizumab-Bevacizumab Versus Tyrosin Kinase Inhibitors in Patients With Liver Cirrhosis
A completed clinical trial assesses safety and efficacy of the atezolizumab‑bevacizumab combination versus tyrosine kinase inhibitors in pat…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Affordable Made-in-India Microspheres for Liver Cancer Therapy [Phase 1]
A Phase 1 clinical trial in India is planned to evaluate microsphere-based therapy for hepatocellular carcinoma, with status listed as not y…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Imfinzi/Imjudo uHCC Japan PMS _ Japan Post-Marketing Surveillance (PMS) Study
A post-marketing surveillance study in Japan evaluating the combination of durvalumab (Imfinzi) and tremelimumab (Imjudo) for unresectable h…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Effects of Neoadjuvant Immunotherapy on Anti-tumour Immunity in Hepatocellular Carcinoma Patients Undergoing Liver Resection [Phase 3]
A Phase 3 trial is evaluating neoadjuvant immunotherapy to enhance anti-tumor immunity in patients with hepatocellular carcinoma undergoing …
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Study Evaluating the Benefit of Adding Ipilimumab to the Combination of Atezolizumab and Bevacizumab in Patients With Hepatocellular Carcinoma Receiving First-line Systemic Therapy [Phase 2, Phase 3]
A phase 2/3 trial evaluated adding ipilimumab to the combination of atezolizumab and bevacizumab as first-line therapy for hepatocellular ca…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: A Phase I/II Study to Evaluate AZD5851 in GPC3+ Advanced/Recurrent Hepatocellular Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating AZD5851 in GPC3-positive advanced or recurrent hepatocellular carcinoma, with the study currently acti…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Regorafenib-pembrolizumab vs. TACE/TARE in Intermediate Stage HCC Beyond Up-to-7 [Phase 3]
A Phase 3 trial comparing regorafenib-pembrolizumab versus TACE/TARE in intermediate-stage hepatocellular carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors [Phase 1]
Phase 1 trial evaluating IL-15 armored glypican-3–specific CAR-T cells for solid tumors, including hepatocellular carcinoma and several pedi…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Assess Efficacy and Safety of Durvalumab Alone or Combined With Bevacizumab in High Risk of Recurrence HCC Patients After Curative Treatment [Phase 3]
A Phase 3 clinical trial evaluating durvalumab alone or with bevacizumab for hepatocellular carcinoma at high risk of recurrence after curat…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Study Of Intrabucally Administered Electromagnetic Fields and Regorafenib [Phase 2]
A Phase 2 study evaluating intrabuccally administered electromagnetic fields in combination with regorafenib for hepatocellular carcinoma wa…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: A Study of AK112 in Patients With Unresectable Hepatocellular Carcinoma (HCC) [Phase 2]
This is a completed Phase 2 clinical trial evaluating AK112 in patients with unresectable hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: CECT Features of MVI Predict Response to TACE Plus TKI in Intermediate-stage HCC
The completed trial examines whether CT features of microvascular invasion can predict response to transarterial chemoembolization plus a ty…