Hepatocellular Carcinoma

• CLINICAL_TRIALS trial_result · 2023-09-08
  Clinical Trial Update: The Clinical Significance of Peripheral Blood T Lymphocyte PD-1 Expression and T Cell Subset Distribution. [Phase 2]

  Phase 2 clinical trial update examining the significance of peripheral blood T lymphocyte PD-1 expression and T cell subset distribution in …

• CLINICAL_TRIALS trial_result · 2023-08-30
  Clinical Trial Update: Low Dose ICG for Biliary Tract and Tumor Imaging [Phase 2]

  Phase 2 trial evaluating low-dose indocyanine green (ICG) for biliary tract and tumor imaging completed with results posted.

• CLINICAL_TRIALS trial_result · 2023-08-23
  Clinical Trial Update: HAIC Combined With Durvalumab, Tremelimumab and Bevacizumab as Conversion Therapy for Potentially Resectable Hepatocellular Carcinoma [Phase 2]

  Phase 2 trial assessing hepatic arterial infusion chemotherapy combined with durvalumab, tremelimumab, and bevacizumab as conversion therapy…

• CLINICAL_TRIALS trial_result · 2023-08-22
  Clinical Trial Update: BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer [Phase 1, Phase 2]

  Clinical trial evaluating BMS-986205 in combination with nivolumab for hepatocellular carcinoma across first- or second-line settings; study…

• CLINICAL_TRIALS trial_result · 2023-08-18
  Clinical Trial Update: Trial of Beads Versus Doxorubicin Eluting Beads for Arterial Embolization of Hepatocellular Carcinoma [Phase 2]

  Phase 2 trial comparing Beads versus Doxorubicin-eluting Beads for arterial embolization in hepatocellular carcinoma has completed with resu…

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• CLINICAL_TRIALS trial_result · 2023-08-15
  Clinical Trial Update: A Trial of Conversion Treatment of HAIC Combined With Camrelizumab and Apatinib for Unresected Hepatocellular Carcinoma [Phase 2]

  Phase 2 clinical trial evaluating hepatic arterial infusion chemotherapy with camrelizumab and apatinib for unresected hepatocellular carcin…

• CLINICAL_TRIALS trial_result · 2023-08-15
  Clinical Trial Update: HAIC Plus Toripalimab vs. HAIC Plus Sorafenib for HCC With PVTT: a Non-comparative, Prospective, Randomized Trial [Phase 2]

  Phase 2 trial evaluating HAIC plus toripalimab versus HAIC plus sorafenib in hepatocellular carcinoma with portal vein tumor thrombosis (PVT…

• CLINICAL_TRIALS trial_result · 2023-08-14
  Clinical Trial Update: Evaluate the Safety and Efficacy of Toripalimab Combined With Bevacizumab Versus Sorafenib Therapy for HCC [Phase 3]

  Phase 3 trial evaluating toripalimab plus bevacizumab versus sorafenib for advanced hepatocellular carcinoma.

• CLINICAL_TRIALS trial_result · 2023-08-14
  Clinical Trial Update: Sintilimab+Bevacizumab+TACE vs. Lenvatinib+TACE for Advanced HCC [Phase 3]

  Phase 3 trial comparing Sintilimab+Bevacizumab+TACE versus Lenvatinib+TACE for advanced hepatocellular carcinoma non-resectable; currently r…

• CLINICAL_TRIALS trial_result · 2023-08-04
  Clinical Trial Update: A Study of QL1706 in Combination With Bevacizumab and/or Chemotherapy as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma [Phase 2, Phase 3]

  A clinical trial update for QL1706 in combination with bevacizumab and/or chemotherapy as first-line therapy for advanced hepatocellular car…

• CLINICAL_TRIALS trial_result · 2023-08-02
  Clinical Trial Update: Phase II Study of Fruquintinib Combined With Sintilimab and TACE for Inoperable Primary Hepatocellular Carcinoma [Phase 2]

  A Phase II clinical trial evaluating the combination of Fruquintinib, Sintilimab, and TACE for inoperable primary hepatocellular carcinoma.

• CLINICAL_TRIALS trial_result · 2023-07-27
  Clinical Trial Update: Study of BGB-A317 in Participants With Previously Treated Unresectable HCC [Phase 2]

  Phase 2 trial of BGB-A317 in previously treated unresectable hepatocellular carcinoma has completed with results posted.

• CLINICAL_TRIALS trial_result · 2023-07-24
  Clinical Trial Update: Safety and Efficacy of Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) Versus Lenvatinib as First-line Therapy in Participants With Advanced Hepatocellular Carcinoma (MK-7902-002/E7080-G000-311/LEAP-002) [Phase 3]

  Phase 3 LEAP-002 trial comparing lenvatinib plus pembrolizumab versus lenvatinib alone as first-line therapy for advanced hepatocellular car…

• CLINICAL_TRIALS trial_result · 2023-07-20
  Clinical Trial Update: Transarterial Chemoembolization in Combination With Nivolumab Performed for Intermediate Stage Hepatocellular Carcinoma [Phase 2]

  Phase 2 trial evaluating transarterial chemoembolization combined with nivolumab for intermediate-stage hepatocellular carcinoma has complet…

• CLINICAL_TRIALS trial_result · 2023-07-13
  Clinical Trial Update: Donafenib Combined With Hepatic Artery Chemoembolization for Perioperative Treatment of Liver Transplantation [Phase 2]

  A Phase 2 clinical trial evaluating donafenib in combination with hepatic artery chemoembolization as perioperative treatment in liver trans…

• CLINICAL_TRIALS trial_result · 2023-07-11
  Clinical Trial Update: Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers [Phase 2]

  Phase 2 clinical trial evaluating nivolumab with tadalafil and oral vancomycin in patients with refractory hepatocellular carcinoma or liver…

• CLINICAL_TRIALS trial_result · 2023-07-11
  Clinical Trial Update: Feasibility 3D Perfusion Ultrasound for Liver Cancer SABR Planning and Response Evaluation [NA]

  A completed feasibility study on 3D perfusion ultrasound for planning and evaluating response to SBRT in liver cancer patients.

• CLINICAL_TRIALS trial_result · 2023-07-10
  Clinical Trial Update: Nivolumab With or Without Ipilimumab in Treating Patients With Resectable Liver Cancer [Phase 2]

  Phase 2 trial evaluating nivolumab with or without ipilimumab in patients with resectable hepatocellular carcinoma has completed; results po…

• CLINICAL_TRIALS trial_result · 2023-07-03
  Clinical Trial Update: Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer [Phase 3]

  Phase 3 trial evaluating whether adding stereotactic body radiation therapy to sorafenib improves outcomes in adults with hepatocellular car…

• CLINICAL_TRIALS trial_result · 2023-07-03
  Clinical Trial Update: Phase Ib/II Study of INC280 + PDR001 or PDR001 Single Agent in Advanced HCC [Phase 1, Phase 2]

  Phase Ib/II trial investigating INC280 plus PDR001 or PDR001 alone in advanced hepatocellular carcinoma has completed with results posted.

• CLINICAL_TRIALS trial_result · 2023-06-29
  Clinical Trial Update: Cadonilimab Plus TACE in Patients With Intermediate-stage Unresectable Hepatocellular Carcinoma [Phase 2]

  Phase 2 trial update for cadonilimab plus TACE in intermediate-stage unresectable hepatocellular carcinoma is reported, with status currentl…

• CLINICAL_TRIALS trial_result · 2023-06-28
  Clinical Trial Update: Electromagnetic Fields Versus Placebo For Child-Pugh A and B Patients With Advanced Hepatocellular Carcinoma [Phase 2, Phase 3]

  A clinical trial investigating electromagnetic fields versus placebo in advanced hepatocellular carcinoma (Child-Pugh A and B) across Phase …

• CLINICAL_TRIALS trial_result · 2023-06-27
  Clinical Trial Update: Cryoablation Combined With Tislelizumab Plus Lenvatinib in 1L Treatment of Advanced HCC (CASTLE-10) [Phase 2]

  Phase 2 trial exploring cryoablation with tislelizumab and lenvatinib as first-line therapy for advanced hepatocellular carcinoma.

• CLINICAL_TRIALS trial_result · 2023-06-26
  Clinical Trial Update: Efficacy and Safety of 'Immuncell-LC Group' and 'Non-treatment Group' in Nexavar Treated Patients for Advanced HCC [Phase 2]

  Phase 2 trial assessing efficacy and safety of Immuncell-LC Group versus non-treatment in Nexavar-treated patients with advanced hepatocellu…

• CLINICAL_TRIALS trial_result · 2023-06-22
  Clinical Trial Update: DEB-TACE+HAIC vs. HAIC for Large HCC [Phase 3]

  Phase 3 trial update comparing DEB-TACE+HAIC versus HAIC for unresectable hepatocellular carcinoma.