Hepatocellular Carcinoma
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Cabozantinib in Patients With Advanced Hepatocellular Carcinoma With Child Pugh Class B Cirrhosis After First-Line Therapy [Phase 1, Phase 2]
Phase 1/2 trial update on cabozantinib for advanced hepatocellular carcinoma with Child-Pugh B cirrhosis after first-line therapy. The study…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Measuring and Improving the Safety of Test Result Follow-Up [NA]
This clinical trial update reports the completion and posting of results for a study assessing methods to measure and improve safety in the …
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: HELIO Liver Test Performance Study in China (HEPATIC)
The HELIO Liver Test Performance Study in China (HEPATIC) has completed per the trial status update. Sponsor is Helio Genomics.
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Neoadjuvant and Adjuvant Nivolumab in HCC Patients Treated by Electroporation [Phase 2]
This document reports the completion of a Phase 2 clinical trial evaluating nivolumab as neoadjuvant and adjuvant therapy for hepatocellular…
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CLINICAL_TRIALS trial_result · 2024-07-26Clinical Trial Update: Hepatic Intra-Arterial Administration of Ipilimumab in Combination With Intra-venous Nivolumab for Advanced Hepatocellular Carcinoma [Phase 1]
Phase 1 trial evaluating hepatic intra-arterial ipilimumab in combination with intravenous nivolumab for advanced hepatocellular carcinoma i…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: HAIC Plus Sorafenib Versus TACE Plus Sorafenibfor Advanced HCC [Phase 3]
Phase 3 trial comparing hepatic arterial infusion chemotherapy (HAIC) plus sorafenib versus transarterial chemoembolization (TACE) plus sora…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: MGD013 Monotherapy and Combination With Brivanib Dose Escalation and Expansion Study in Advanced Liver Cancer Patients [Phase 1, Phase 2]
This clinical trial update reports termination of the MGD013 monotherapy and MGD013 with brivanib dose escalation/expansion study in advance…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of Lenvatinib in Participants With Advanced or Unresectable Hepatocellular Carcinoma
This entry notes the completion of a clinical trial evaluating the safety and tolerability of lenvatinib in participants with advanced or un…
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: A Study of Pembrolizumab and Bavituximab in Patients With Advanced Hepatocellular Carcinoma [Phase 2]
A Phase 2 study evaluating pembrolizumab in combination with bavituximab for advanced hepatocellular carcinoma, with results posted and the …
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Long-term Management of Patients With Ruptured HCC
This entry provides an update on the long-term management of patients with ruptured hepatocellular carcinoma from a completed clinical trial…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer [Phase 1]
Phase 1 trial evaluating the addition of pembrolizumab to standard antiretroviral therapy in HIV-positive patients with cancer. The study ha…
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Pembrolizumab and Lenvatinib for Resectable Hepatocellular Carcinoma [Phase 2]
A Phase 2 clinical trial update evaluating the combination of pembrolizumab and lenvatinib for resectable hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Robotic Versus Laparoscopic Liver Resection for Hepatocellular Carcinoma
A completed clinical trial sponsored by Ente Ospedaliero Cantonale in Bellinzona compared robotic-assisted liver resection to laparoscopic l…
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors [NA]
A terminated clinical trial evaluating LC Bead LUMI radiopaque embolic beads for detecting and characterizing hepatic tumor vascularity has …
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: Nivolumab Plus Ipilimumab as Neoadjuvant Therapy for Hepatocellular Carcinoma (HCC) [Phase 2]
Phase 2 trial evaluating nivolumab plus ipilimumab as neoadjuvant therapy for hepatocellular carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) [Phase 1]
This update reports the completion of a Phase 1 study (DUET-3) evaluating XmAb23104 in patients with selected advanced solid tumors.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: HCC Screening Using DNA Methylation Changes in ctDNA
A completed clinical trial evaluating hepatocellular carcinoma screening using DNA methylation changes in circulating tumor DNA; results wer…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Lenvatinib After Progression on Atezolizumab-bevacizumab in Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial evaluating lenvatinib after progression on atezolizumab-bevacizumab for hepatocellular carcinoma is currently active …
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Checkpoint Inhibitor Combinations Therapy as First Line for HCC Via IT [Phase 2]
A Phase 2 clinical trial is evaluating first-line checkpoint inhibitor combination therapy for hepatocellular carcinoma and is currently rec…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Intratumor CpG-ODN Injection Boosters Immune Killing Against in Situ Tumor Antigen Release for Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating intratumoral CpG-ODN injections to boost immune killing and in situ tumor antigen release in advanced soli…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: TACE, Sorafenib and PD-1 Monoclonal Antibody in the Treatment of HCC [Phase 2]
Phase 2 trial evaluating the combination of transarterial chemoembolization (TACE), sorafenib, and a PD-1 monoclonal antibody for hepatocell…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy [NA]
This completed University of Maryland study evaluated whether postoperative heme oxygenase induction and carbon monoxide production can asse…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Study of SHR-8068 Combined With Adebrelimab and Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating SHR-8068 combined with Adebrelimab and Bevacizumab for advanced hepatocellular carcinoma is currently re…
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: A Study of Lenvatinib Plus Nivolumab in Participants With Hepatocellular Carcinoma [Phase 1]
Phase 1 study of lenvatinib plus nivolumab in hepatocellular carcinoma has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-06-17Clinical Trial Update: RFA Versus SBRT for Recurrent Small HCC [Phase 3]
A Phase 3 trial comparing radiofrequency ablation (RFA) versus stereotactic body radiotherapy (SBRT) for recurrent small hepatocellular carc…