Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Donafenib Plus Sintilimab for Advanced HCC [Phase 2]
A Phase 2 trial evaluating donafenib in combination with sintilimab for advanced hepatocellular carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Sorafenib and Nivolumab in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer [Phase 2]
Phase 2 trial evaluating sorafenib plus nivolumab in unresectable, locally advanced, or metastatic hepatocellular carcinoma has completed an…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Prognostic Factors for HCC and Liver Transplantation in Patients With MASLD/MASH
A clinical trial evaluating prognostic factors for hepatocellular carcinoma and liver transplantation in patients with MASLD/MASH; recruitme…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Study of Pembrolizumab Following TACE in Primary Liver Carcinoma [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating pembrolizumab following transarterial chemoembolization in hepatocellular carcinoma to assess safety …
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 (Erdafitinib) in Participants With Advanced Hepatocellular Carcinoma [Phase 1, Phase 2]
A Phase 1/2 study evaluating erdafitinib (JNJ-42756493) in patients with advanced hepatocellular carcinoma has completed, assessing safety, …
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Phase 1/2 Study to Evaluate OTX-2002 in Patients with Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association with the MYC Oncogene [Phase 1, Phase 2]
Phase 1/2 study of OTX-2002 in hepatocellular carcinoma and other solid tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Dose Escalation Study of Cabozantinib for Advanced HCC Patients With Preserved Liver Function [Phase 2]
A Phase 2 dose-escalation trial of cabozantinib in advanced hepatocellular carcinoma with preserved liver function has completed, focusing o…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Cabozantinib for Patients with Hepatocellular Carcinoma (HCC) Refractory to First Line Treatment [Phase 2]
A Phase 2 trial of cabozantinib for hepatocellular carcinoma refractory to first-line therapy has completed, including non-resectable or met…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Ex-vivo Hypotermic Perfusion in Patients With Hepatocellular Carcinoma to Reduce the Incidence of Tumor Recurrence
Completed clinical trial evaluating ex-vivo hypothermic, oxygenated machine perfusion of donor livers in hepatocellular carcinoma patients u…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Establishment of Molecular Classification Models for Early Diagnosis of Digestive System Cancers
This completed trial developed molecular classification models for early diagnosis of digestive system cancers and assessed their ability to…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: SIR-Spheres Study to Calculate the Radiation-Absorbed Dose of 99mTc-MAA [Phase 4]
Sirtex Medical conducted a Phase 4 trial to calculate the radiation-absorbed dose of 99mTc-MAA used in planning SIR-Spheres Y-90 microsphere…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Validation of the TRAIN-AI for the Risk of HCC Recurrence After Liver Transplantation
This update reports the completed validation study of TRAIN-AI, an AI model, for predicting hepatocellular carcinoma recurrence after liver …
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Single-arm, Open-label Clinical Study of SZ003 in the Treatment of Advanced Hepatocellular Carcinoma [NA]
A single-arm, open-label study of SZ003 for advanced hepatocellular carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Cabozantinib Treatment in a Phase II Study for Patients With Hepatocellular Carcinoma (HCC) Refractory to PD-1 Inhibitors [Phase 2]
A Phase II trial of cabozantinib for hepatocellular carcinoma refractory to PD-1 inhibitors has completed.
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: The Favorable Impact of HBcAb Positive Grafts on Liver Transplantation for HBV-related HCC
A completed clinical trial update reports favorable outcomes with HBcAb-positive donor grafts in liver transplantation for HBV-related hepat…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Atezolizumab and Bevacizumab in Combination With TACE for Patients With BCLC B HCC [Phase 2]
A Phase 2 trial evaluating Atezolizumab with Bevacizumab in combination with transarterial chemoembolization for patients with BCLC B hepato…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Recurrence Patterns and Cost-Effectiveness of Surgical Approaches in Early-Stage Hepatocellular Carcinoma
This trial completion update analyzes recurrence patterns and cost-effectiveness of different surgical approaches for early-stage hepatocell…
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: Circulating Cell-free DNA-based Epigenetic Biomarker MSEPT9 for Hepatocellular Carcinoma Detection in Cirrhosis [NA]
This clinical trial update reports on using circulating cell-free DNA methylation biomarker MSEPT9 to detect hepatocellular carcinoma in pat…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Study of Oligo-Fucoidan in Advanced Hepatocellular Carcinoma (HCC) [NA]
A clinical trial evaluating Oligo-Fucoidan for advanced hepatocellular carcinoma has been terminated; no results are provided in the update.
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Composite Warming Strategy Reduces Intraoperative Hypothermia in Open Hepatectomy for Liver Cancer [NA]
A clinical trial update reports that a composite warming strategy reduces intraoperative hypothermia during open hepatectomy for hepatocellu…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver [Phase 2]
Phase 2 clinical trial results update evaluating pevonedistat in combination with chemotherapy for biliary tract cancers (cholangiocarcinoma…
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Microvascular Invasion Artificial Intelligence Prediction Via Contrast-enhanced Ultrasound With Explainability
A completed clinical trial update investigates AI-based prediction of microvascular invasion in hepatocellular carcinoma using contrast-enha…
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Study of Y90-Radioembolization With Nivolumab in Asians With Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating Y90-radioembolization with nivolumab in Asians with hepatocellular carcinoma. The study is currentl…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors [Phase 2]
Phase 2 trial evaluating neoadjuvant dual checkpoint inhibition with cryoablation in relapsed/refractory pediatric solid tumors has complete…
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CLINICAL_TRIALS trial_result · 2024-12-30Clinical Trial Update: Harms of Hepatocellular Carcinoma Surveillance
A completed clinical trial assessing the adverse harms associated with surveillance for hepatocellular carcinoma.