Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: FMT in IT-refractory HCC - FAB-HCC Pilot Study [Phase 2]
Phase 2 FAB-HCC Pilot Study completed evaluating fecal microbiota transplant for hepatocellular carcinoma that is refractory to immune thera…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Contrast-Enhanced Ultrasound in Predicting Treatment Response in Patients With Liver Cancer Receiving Transarterial Chemoembolization With Drug Eluting Beads [Phase 1]
A completed Phase 1 trial evaluating whether contrast-enhanced ultrasound can predict treatment response in hepatocellular carcinoma patient…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: TheraSphere for the Treatment of Unresectable Hepatocellular Carcinoma
The clinical trial NCT01349075 evaluating TheraSphere for unresectable hepatocellular carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: Blood Sample Collection for Experimental Blood Test to Track Liver Cancer
A completed clinical trial update describing blood sample collection for an experimental blood test to monitor hepatocellular carcinoma.
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: A Clinical Trial for the Safety and Efficacy of CD-801 in Patients With Advanced Hepatocellular Carcinoma [EARLY_Phase 1]
An early-phase trial evaluating the safety and efficacy of CD-801 in patients with advanced hepatocellular carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Implication of Long Non-coding RNA HOTTIP Haplotype on Liver Cancer Metastasis
A completed clinical trial update investigates whether the haplotype of the long non-coding RNA HOTTIP influences metastasis in hepatocellul…
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: Radioembolization as a Spearhead Treatment of Hepatocellular Carcinoma With Localized Portal Vein Tumor Thrombosis [Phase 2]
A Phase 2 clinical trial is evaluating radioembolization as a spearhead treatment for hepatocellular carcinoma with localized portal vein tu…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Microbiota Study in Liver Transplanted Patients
A microbiota-focused clinical trial in patients with cirrhosis and hepatocellular carcinoma undergoing liver transplantation has completed.
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Ezurpimtrostat Autophagy Inhibitor in Association With Atezolizumab-Bevacizumab in First Line Treatment of Unresectable Hepatocellular Carcinoma [Phase 2]
A Phase 2 trial evaluating Ezurpimtrostat with atezolizumab-bevacizumab as first-line therapy for unresectable hepatocellular carcinoma has …
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: A Multi-center, Open-label Study of Oral ENMD-2076 for the Treatment of Patients With Advanced Fibrolamellar Carcinoma [Phase 2]
Phase 2 open-label study of ENMD-2076 in patients with advanced fibrolamellar hepatocellular carcinoma and advanced hepatocellular carcinoma…
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis [Phase 2]
Phase 2 trial evaluating simvastatin to prevent hepatocellular carcinoma in patients with liver cirrhosis; results have been posted and the …
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC) [Phase 2]
Phase 2 study of YIV-906 in combination with Sorafenib for HBV-positive hepatocellular carcinoma has completed. It investigates the use of Y…
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: A First-in-Human Study to Learn About How BAY3630942 is Distributed and Processed Inside the Body When Given After BAY3547922 and How Safe it is in People With Liver Cancer or Other Select Solid Cancers [Phase 1]
A Phase 1 first-in-human study evaluated BAY3630942 after BAY3547922, focusing on distribution, pharmacokinetics, and safety. The trial in h…
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: SIRT or TACE Plus Lenvatinib and PD-(L)1 Inhibitor in High Burden HCC
A study evaluating SIRT or TACE in combination with lenvatinib and a PD-1/PD-L1 inhibitor for unresectable hepatocellular carcinoma has comp…
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CLINICAL_TRIALS trial_result · 2025-04-07Clinical Trial Update: Lenvatinib Treatment in Waiting List of Liver Transplantation After TACE Failure in Patients With Hepatocellular Carcinoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating lenvatinib for patients with non-resectable hepatocellular carcinoma on the liver transplant waiting lis…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies [Phase 1, Phase 2]
Phase 1/2 open-label study evaluating Alomfilimab (KY1044) alone and with atezolizumab in multiple advanced cancers. The trial was terminate…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Dexmedetomidine-esketamine for Percutaneous Radiofrequency Liver Ablation [NA]
The clinical trial update indicates completion of a study evaluating the combination of dexmedetomidine and esketamine for sedation during p…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Cabozantinib in Patients With Hepatocellular Carcinoma (ACTION) [Phase 2]
The ACTION Phase 2 trial evaluating cabozantinib in hepatocellular carcinoma has completed, with results posted on 2025-03-30.
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Single-Cell Profiling of Liver-infiltrating Immune Cells of Patients with NASH- and Virus-related HCC: Implications for Immunotherapy
A completed single-cell profiling study of liver-infiltrating immune cells in hepatocellular carcinoma associated with MASLD or hepatitis C …
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Atezolizumab and Bevacizumab Combination Recommended in a Multidisciplinary Consultation Meeting in Caen for Hepatocellular Carcinoma (ABCHCaen)
The clinical trial evaluating atezolizumab plus bevacizumab for hepatocellular carcinoma has completed, and the combination was recommended …
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: HAIC Compared With TACE in Huge Hepatocellular Carcinoma
Sun Yat-sen University is sponsoring a clinical trial comparing hepatic arterial infusion chemotherapy (HAIC) with transarterial chemoemboli…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers [Phase 1]
Phase 1 study of the oral STAT3 inhibitor TTI-101 in patients with advanced cancers has completed, with enrollment across multiple tumor typ…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: A Study of Participants With Initially Unresectable Hepatocellular Carcinoma That is Treated With Atezolizumab and Bevacizumab Plus Transarterial Chemoembolization
This clinical trial update reports on a completed study evaluating the combination of atezolizumab and bevacizumab with transarterial chemoe…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study) [NA]
PLATON, a platform for analyzing targetable tumor mutations, completed its pilot study evaluating its utility across hepatocellular carcinom…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Blood Salvage in Orthotopic Liver Transplantation With HCC [NA]
Clinical trial update on blood salvage during orthotopic liver transplantation for hepatocellular carcinoma; the study is currently active a…