Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Construction and Clinical Validation of a Predictive Model for Postoperative Adjuvant Therapy in Hepatocellular Carcinoma Based on Whole-Slide Digital Pathological Images and Deep Learning [NA]
This clinical trial aims to construct and clinically validate a predictive model using whole-slide digital pathology and deep learning to gu…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Tislelizumab Combined With Huaier Granule as First-line Treatment for Unresectable Hepatocellular Carcinoma [Phase 2]
A Phase 2 trial is investigating tislelizumab in combination with Huaier granule as first-line therapy for unresectable hepatocellular carci…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells [Phase 1]
Phase 1 pediatric trial of interleukin-15 and interleukin-21 armored glypican-3–specific CAR T cells for solid tumors, including liver-origi…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Biobank for Cholestatic Liver Diseases.
Mayo Clinic is recruiting for a biobank study of cholestatic liver diseases, including primary sclerosing cholangitis and primary biliary ch…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab [Phase 3]
Phase 3 study evaluating atezolizumab plus lenvatinib or sorafenib versus lenvatinib or sorafenib alone in unresectable hepatocellular carci…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Lenvatinib and Pembrolizumab With or Without BCAA in Unresectable HCC [Phase 2]
A Phase 2 study evaluating Lenvatinib with Pembrolizumab, with or without branched-chain amino acids, for unresectable hepatocellular carcin…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Surgery vs. Watch-and-Wait Strategy in Complete Responders for Hepatocellular Carcinoma (SWITCH)
Clinical SWITCH trial examines surgery versus watch-and-wait in complete responders with hepatocellular carcinoma; the study is currently no…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Comparison of Response Between Combination of Transarterial Chemoembolization and Lenvatinib Therapy Versus Lenvatinib Monotherapy in Patients With Unresectable Hepatocellular Carcinoma [NA]
Clinical trial comparing combination therapy of transarterial chemoembolization plus lenvatinib versus lenvatinib alone in unresectable hepa…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study [Phase 2]
A Phase 2 trial (The Knight SHIFT Study) is comparing morning versus afternoon administration of immunotherapy for advanced or metastatic so…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: "Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".
A French research trial aims to assemble a biological collection to develop preclinical translational models for tumors and chronic liver di…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: REGULUS: MRI-guided Adaptive SABR for Liver Cancers [Phase 2]
Stanford's REGULUS trial investigates MRI-guided adaptive SABR for liver cancers, including hepatocellular carcinoma and intrahepatic cholan…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: A Study Evaluating Cadonilimab Injection in Combination With Regorafenib for the Advanced Hepatocellular Carcinoma [Phase 1]
This Phase 1 trial investigates Cadonilimab in combination with Regorafenib for advanced hepatocellular carcinoma that has failed at least o…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Phase II Trial of Immunonutrition in Hepatectomy [NA]
This update describes a Phase II trial evaluating immunonutrition in patients undergoing hepatectomy for hepatocellular carcinoma, currently…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: A Clinical Study of SH006 Injection in Combination Therapy Versus Regorafenib in the Treatment of Advanced Hepatocellular Carcinoma [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial comparing SH006 Injection in combination therapy to Regorafenib for advanced hepatocellular carcinoma, with…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Monitoring Circulating Tumor DNA [NA]
A clinical trial is investigating whether monitoring circulating tumor DNA can predict recurrence of hepatocellular carcinoma after curative…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Registry on Percutaneous Electrochemotherapy
A clinical trial registry update for a percutaneous electrochemotherapy study in primary and secondary liver cancers, sponsored by the Cardi…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: PSYLIVER-PILOTE: Involvement of the Autonomic Nervous System in Hepatocellular Carcinoma (HCC) [NA]
ClinicalTrials.gov entry PSYLIVER-PILOTE describes research on autonomic nervous system involvement in hepatocellular carcinoma, with the st…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: MDN-001 Injection for the Treatment of Unresectable Primary Hepatocellular Carcinoma. [Phase 1]
Phase 1 study of MDN-001 Injection for unresectable primary hepatocellular carcinoma is currently recruiting. The sponsor is Suzhou Mednovo …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: A Study of SH009 Injection in Patients With Advanced Solid Tumors. [Phase 1]
A Phase 1 clinical trial update for SH009 Injection in patients with advanced solid tumors, currently recruiting across multiple indications…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Exploratory Blood-Based Biomarkers in TACE-Treated Hepatocellular Carcinoma
An ongoing clinical trial in Belgrade is investigating blood-based biomarkers in hepatocellular carcinoma patients treated with transarteria…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers [Phase 1]
Phase 1 exploratory study evaluating FAPi PET/CT imaging with histopathology validation in patients with various cancers. The trial collects…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: NIS on the Benefits of TIPS in Patients With HCC Receiving Atezo+Bev in 1st-Line Therapy
A non-interventional study is investigating the benefits of applying Transjugular Intrahepatic Portosystemic Shunt (TIPS) in hepatocellular …
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Project OASIS: Optimizing Approaches to Select Implementation Strategies [NA]
A VA-sponsored update on the PROJECT OASIS trial, aiming to optimize implementation strategies; the study is currently enrolling by invitati…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Durvalumab and Tremelimumab With or Without Hepatic Arterial Infusion of Chemotherapy in Hepatocellular Carcinoma [Phase 2, Phase 3]
A phase 2/3 trial evaluating durvalumab and tremelimumab with or without hepatic arterial infusion chemotherapy in hepatocellular carcinoma.…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients [NA]
An update on a clinical trial assessing SIR-Spheres Y-90 resin microspheres for unresectable hepatocellular carcinoma, focusing on duration …