Hepatocellular Carcinoma

CLINICAL_TRIALS research · 2026-03-16

Clinical Trial Update: Evaluation of the Interest to Combine a CD4 Th1-inducer Cancer Vaccine Derived From Telomerase and Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma [Phase 2]

Phase 2 trial evaluating the addition of a telomerase-derived CD4 Th1-inducer cancer vaccine to atezolizumab plus bevacizumab in unresectabl…

CLINICAL_TRIALS research · 2026-03-16

Clinical Trial Update: A Study of Neoadjuvant Tislelizumab Plus Lenvatinib in Resectable HCC at High Risk of Recurrence [Phase 3]

This is a Phase 3 clinical trial update on neoadjuvant tislelizumab plus lenvatinib for resectable hepatocellular carcinoma at high risk of …

CLINICAL_TRIALS research · 2026-03-13

Clinical Trial Update: Biannual Screening for HCC Offered to Patients With Cirrhosis. Introducing Surveillance for Hepatocellular Carcinoma (HCC) in the Central Denmark Region Using Ultrasound and Alpha-Fetoprotein to Reduce HCC-Related Mortality in Patients With Compensated Non-Viral Cirrhosis [NA]

This clinical trial update describes a program in the Central Denmark Region that offers biannual ultrasound and alpha-fetoprotein screening…

CLINICAL_TRIALS research · 2026-03-13

Clinical Trial Update: A Pilot Study of Liver Protection Using Prednisone for Patients Receiving Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma [Phase 2]

Phase 2 clinical trial update describing a pilot study of prednisone for liver protection in patients with hepatocellular carcinoma receivin…

CLINICAL_TRIALS research · 2026-03-12

Clinical Trial Update: Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors [Phase 1]

A Phase 1 study evaluating Zanzalintinib in combination with immuno-oncology agents in patients with various solid tumors; recruitment is on…

CLINICAL_TRIALS research · 2026-03-12

Clinical Trial Update: FAST-IRM for HCC suRveillance in pAtients With High risK of Liver Cancer. [NA]

A clinical trial update indicates FAST-IRM is being studied for hepatocellular carcinoma surveillance in high-risk liver cancer patients and…

CLINICAL_TRIALS research · 2026-03-12

Clinical Trial Update: HAIC Plus Lenva and PD-1 for Advanced HCC With Macrovascular or Biliary Invasion

Clinical trial update evaluating hepatic arterial infusion chemotherapy with lenvatinib and a PD-1 inhibitor for advanced hepatocellular car…

CLINICAL_TRIALS research · 2026-03-11

Clinical Trial Update: A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 02(BTC&HCC)] [Phase 2]

Phase 2 clinical study of LBL-024 in combination therapy for advanced solid tumors is currently recruiting, with substudy focusing on biliar…

CLINICAL_TRIALS research · 2026-03-11

Clinical Trial Update: PULSAR Combined With Fecal Microbiota Transplantation for Advanced Hepatocellular Carcinoma Progressing After First-Line Targeted-Immunotherapy [Phase 2]

This document announces a Phase 2 clinical trial evaluating PULSAR in combination with fecal microbiota transplantation for advanced hepatoc…

CLINICAL_TRIALS research · 2026-03-11

Clinical Trial Update: The Safety and Efficacy of Ondansetron in Reducing Immune Checkpoint Inhibitor-Related Toxicities [Phase 2]

A Phase 2 clinical trial evaluating whether ondansetron can reduce immune checkpoint inhibitor–related toxicities in hepatocellular carcinom…

CLINICAL_TRIALS research · 2026-03-10

Clinical Trial Update: Safety of Atezolizumab-Bevacizumab in Liver Transplanted Patients With Advanced Hepatocellular Carcinoma [Phase 2]

Phase 2 clinical trial assessing safety of the atezolizumab-bevacizumab combination in liver transplant recipients with advanced hepatocellu…

CLINICAL_TRIALS research · 2026-03-10

Clinical Trial Update: Abbreviated MRI Using Gadoxetic Acid Versus CT for Surveillance of Recurrent HCC After Curative Treatment [NA]

A clinical trial evaluating abbreviated MRI with gadoxetic acid versus CT for surveillance of recurrent hepatocellular carcinoma after curat…

CLINICAL_TRIALS research · 2026-03-09

Clinical Trial Update: 18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplant [Phase 1]

This clinical trial update describes a Phase 1 imaging study using 18F-FSPG PET to evaluate liver cancer in patients scheduled for liver res…

CLINICAL_TRIALS research · 2026-03-09

Clinical Trial Update: TriNav Infusion System for the Evaluation of Fidelity Between 99mTc-MAA and Y90-Microspheres Hepatic Distribution for Dosimetry Treatment Planning [NA]

This clinical trial update describes an ongoing study evaluating the fidelity between 99mTc-MAA and Y90-microspheres hepatic distribution fo…

CLINICAL_TRIALS research · 2026-03-09

Clinical Trial Update: Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

An ongoing clinical trial is recruiting to study the frequency and clinical phenotype of BAP1 tumor predisposition syndrome and its associat…

CLINICAL_TRIALS research · 2026-03-09

Clinical Trial Update: Clinical Study on the Safety, Efficacy, and Exploration of Immune Mechanisms of a Combined Multimodal Tumor Therapy System for Hepatic Malignancies [NA]

A clinical trial from Fudan University investigating the safety, efficacy, and immune mechanisms of a combined multimodal tumor therapy for …

CLINICAL_TRIALS research · 2026-03-06

Clinical Trial Update: Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer [Phase 1, Phase 2]

Clinical trial update for a combination of nivolumab, fluorouracil, and interferon alfa-2b in unresectable fibrolamellar hepatocellular carc…

CLINICAL_TRIALS research · 2026-03-06

Clinical Trial Update: Registry 17-009: Multi-Institutional Study Examining Patients With HCC Undergoing Liver Transplantation

This is an update on a multi-institutional registry study of patients with Hepatocellular Carcinoma undergoing liver transplantation. The st…

CLINICAL_TRIALS research · 2026-03-05

Clinical Trial Update: Atezolizumab and Bevacizumab Before Surgery for the Treatment of Resectable Liver Cancer [Phase 2]

Phase 2 trial evaluating neoadjuvant atezolizumab plus bevacizumab before surgery for resectable hepatocellular carcinoma; the study is curr…

CLINICAL_TRIALS research · 2026-03-05

Clinical Trial Update: An Exploratory Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma and Non-Small Cell Lung Cancer With Liver Metastases (INTEGRATE) [Phase 2]

A phase 2 exploratory trial studying the combination of atezolizumab and bevacizumab in hepatocellular carcinoma and metastatic non-small ce…