Hepatocellular Carcinoma

• CLINICAL_TRIALS research · 2026-03-25
  Clinical Trial Update: Phase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid Tumors [Phase 1, Phase 2]

  A Phase Ib/II trial is evaluating the combination of Envafolimab (PD-L1 inhibitor) and lenvatinib in patients with solid tumors, including n…

• CLINICAL_TRIALS research · 2026-03-24
  Clinical Trial Update: GNB4 and Riplet Gene Methylation Combined Detection Kit for Hepatocellular Carcinoma Recurrence Monitoring

  Clinical trial update on a diagnostic kit using GNB4 and Riplet gene methylation to monitor hepatocellular carcinoma recurrence. The study i…

• CLINICAL_TRIALS research · 2026-03-24
  Clinical Trial Update: Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma [Phase 2]

  This update describes a Phase 2 trial evaluating durvalumab, bevacizumab, tremelimumab plus transarterial chemoembolization for hepatocellul…

• CLINICAL_TRIALS research · 2026-03-23
  Clinical Trial Update: Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV [Phase 1]

  This is a Phase 1 clinical trial evaluating the combination of cabozantinib (XL184) and nivolumab in patients with various advanced cancers …

• CLINICAL_TRIALS research · 2026-03-23
  Clinical Trial Update: Atezolizumab and Bevacizumab in Combination With Y^90 Radioembolization in HCC for Liver Transplant [Phase 4]

  Clinical trial update for a Phase 4 study evaluating atezolizumab and bevacizumab in combination with Y-90 radioembolization for hepatocellu…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• CLINICAL_TRIALS research · 2026-03-23
  Clinical Trial Update: cfDNA Methylation for Liver Cancer Recurrence Detection

  A prospective clinical trial is recruiting to evaluate cfDNA methylation as a biomarker for detecting recurrence in primary liver cancer.

• CLINICAL_TRIALS research · 2026-03-20
  Clinical Trial Update: Atezolizumab and Bevacizumab With Proton Radiotherapy for Unresectable Hepatocellular Carcinoma [Phase 2]

  Phase 2 clinical trial evaluating the combination of atezolizumab and bevacizumab with proton radiotherapy for unresectable hepatocellular c…

• CLINICAL_TRIALS research · 2026-03-20
  Clinical Trial Update: Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Longitudinal Monitoring MRD Based on ctDNA

  This clinical trial is evaluating whether longitudinal minimal residual disease monitoring using ctDNA can predict hepatocellular carcinoma …

• CLINICAL_TRIALS research · 2026-03-20
  Clinical Trial Update: Early Detection of Liver Cancer by QUS

  A CHUM-led clinical trial is evaluating quantitative ultrasound for the early detection of hepatocellular carcinoma. The study is currently …

• CLINICAL_TRIALS research · 2026-03-20
  Clinical Trial Update: Association Between Galectin-3 Levels and Outcomes in Patients With Renal Cell Carcinoma, Transitional Cell Carcinoma , Non Small Cell Lung Cancer, and Hepatocellular Carcinoma, Treated With PD-1/PDL-1 Inhibitors

  A clinical trial is investigating whether Galectin-3 levels predict outcomes in patients with renal cell carcinoma, urothelial carcinoma, no…

• CLINICAL_TRIALS research · 2026-03-19
  Clinical Trial Update: Efficacy and Safety of Camrelizumab Plus Rivoceranib and Local Therapy for Hepatocellular Carcinoma With Lung Metastases (CAPLocal) : A Multicentre, Single-Arm,Prospective Cohort Study

  This document outlines the CAPLocal study, a multicentre, single-arm prospective cohort evaluating camrelizumab plus rivoceranib with local …

• CLINICAL_TRIALS research · 2026-03-19
  Clinical Trial Update: A Multicenter Prospective Study on the Performance of Spectral CT for Evaluating Treatment Response After TACE in Hepatocellular Carcinoma

  A multicenter prospective study evaluating the use of spectral CT to assess treatment response after transarterial chemoembolization in hepa…

• CLINICAL_TRIALS research · 2026-03-19
  Clinical Trial Update: A Multicenter Clinical Study of Combined Therapy for Unresectable Hepatocellular Carcinoma [Phase 1, Phase 2]

  This document reports on a multicenter Phase 1/Phase 2 clinical trial evaluating a combined therapy for unresectable hepatocellular carcinom…

• CLINICAL_TRIALS research · 2026-03-19
  Clinical Trial Update: Conversion Therapy With FOLFOX-HAIC Plus Lenvatinib And Tislelizumab For Hepatocellular Carcinoma With Vp3 Portal Vein Tumor Thrombus [Phase 2]

  A Phase 2 trial evaluating conversion therapy with FOLFOX-HAIC plus lenvatinib and tislelizumab for hepatocellular carcinoma with portal vei…

• CLINICAL_TRIALS research · 2026-03-19
  Clinical Trial Update: Phase 2 Study of WGI-0301 for Advanced HCC [Phase 2]

  This document reports an ongoing Phase 2 clinical trial evaluating WGI-0301 for advanced hepatocellular carcinoma, which is currently recrui…

• CLINICAL_TRIALS research · 2026-03-19
  Clinical Trial Update: EUS Glue vs Endoscopic Variceal Band Ligation for Prevention of Rebleeding in Patients With HCC and EV Bleeding: a Retrospective Comparative Study

  A retrospective comparative study evaluating EUS-guided cyanoacrylate injection versus endoscopic variceal band ligation for preventing rebl…

• CLINICAL_TRIALS research · 2026-03-19
  Clinical Trial Update: A US Study to Evaluate Transarterial Radioembolization (TARE) in Combination With Durvalumab and Bevacizumab Therapy in People With Unresectable Hepatocellular Carcinoma Amenable to TARE [Phase 2]

  Phase 2 clinical trial evaluating transarterial radioembolization with durvalumab and bevacizumab for unresectable hepatocellular carcinoma;…

• CLINICAL_TRIALS research · 2026-03-18
  Clinical Trial Update: Prospective Clinical Validation of Next Generation Sequencing (NGS) and Patient-Derived Tumor Organoids (PDO) Guided Therapy in Patients With Advanced/ Inoperable Solid Tumors [NA]

  This document outlines a prospective clinical validation trial using next-generation sequencing and patient-derived tumor organoids to guide…

• CLINICAL_TRIALS research · 2026-03-18
  Clinical Trial Update: A Prospective Study to Evaluate the Safety and Efficacy of the Combination Therapy of Irpagratinib, Atezolizumab, and Bevacizumab in Patients With Hepatocellular Carcinoma [Phase 2]

  A Phase 2 prospective clinical trial is evaluating safety and efficacy of a triplet therapy (Irpagratinib, atezolizumab, and bevacizumab) in…

• CLINICAL_TRIALS research · 2026-03-18
  Clinical Trial Update: MRG006A Combination Therapy for Advanced Hepatocellular Carcinoma (Phase I/II) [Phase 1, Phase 2]

  Phase I/II trial of MRG006A in combination therapy for advanced hepatocellular carcinoma; the study status is not yet recruiting.

• CLINICAL_TRIALS research · 2026-03-18
  Clinical Trial Update: Effect of Fufang Biejiaruangan Combined With Antiviral Therapy on the Incidence of Hepatocellular Carcinoma in Patients With Hepatitis B-related Cirrhosis: A Multicenter, Randomized, Placebo-controlled Study [NA]

  A multicenter randomized controlled trial evaluating whether Fufang Biejiaruangan plus antiviral therapy reduces hepatocellular carcinoma in…

• CLINICAL_TRIALS research · 2026-03-17
  Clinical Trial Update: A Study of SHR-2524 Plus Bevacizumab in the First-line Treatment of Advanced Hepatocellular Carcinoma [Phase 1]

  This is a Phase 1 study evaluating SHR-2524 in combination with bevacizumab as first-line therapy for advanced unresectable hepatocellular c…

• CLINICAL_TRIALS research · 2026-03-16
  Clinical Trial Update: Identification of Innovative Biomarkers to Predict Outcomes in Hepatocellular Carcinoma Treated With Tremelimumab and Durvalumab [NA]

  This clinical trial update reports ongoing research to identify biomarkers that predict outcomes for hepatocellular carcinoma patients treat…

• CLINICAL_TRIALS research · 2026-03-16
  Clinical Trial Update: A Phase II Clinical Study of AK104/AK112 in Combination With TT-00420 Tablet for Advanced HCC. [Phase 2]

  A Phase II clinical trial update indicates the combination of AK104 and AK112 with TT-00420 tablet for advanced hepatocellular carcinoma is …

• CLINICAL_TRIALS research · 2026-03-16
  Clinical Trial Update: Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients [Phase 1, Phase 2]

  An ongoing phase 1/2 pediatric trial examines safety and potential efficacy of a four-drug combination (cyclophosphamide, sorafenib, bevaciz…