Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Prediction and Prognostic Analysis of Liver Abscess Formation After Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma (CHANCE 2407)
A CHANCE 2407 trial investigates prediction and prognosis of liver abscess formation after transarterial chemoembolization in hepatocellular…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Bevacizumab in Combination With Sintilimab Versus Transcatheter Arterial Chemoembolization for the Treatment of Intermediate Stage Hepatocellular Carcinoma (Beyond Up-To-Seven Criteria) [Phase 2]
This entry describes a Phase 2 randomized trial evaluating bevacizumab plus sintilimab versus transarterial chemoembolization for intermedia…
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: HAIC Combined With Adebrelimab Plus Apatinib as the First-line Treatment for HCC in BCLC Stage C: An Open-label, Single-arm, Phase II Study [Phase 2]
This is a Phase II open-label, single-arm trial evaluating hepatic arterial infusion chemotherapy (HAIC) combined with adebrelimab and apati…
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Backline Treatment of Advanced Hepatocellular Carcinoma With Palbociclib [NA]
A clinical trial is evaluating palbociclib as a backline treatment for advanced hepatocellular carcinoma and is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: HAIC Combined With TQB2450 and Anlotinib in Second-line Treatment of Advanced Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating hepatic arterial infusion chemotherapy (HAIC) combined with TQB2450 and Anlotinib for second-line treatment of adva…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression [Phase 1]
Phase 1 trial evaluating GPC3-CAR-T cell therapy for glypican-3 expressing cancers. The study includes hepatocellular carcinoma and squamous…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating engineered tumor-infiltrating lymphocytes (TILs) and CAR-TILs for advanced solid tumors, sponsored by the …
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors [Phase 2, Phase 3]
Clinical trial update for a Phase 2/Phase 3 study examining trans-arterial/intra-tumor infusion of checkpoint inhibitors plus chemotherapy f…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Non-contrast Abbreviated MRI for Secondary Surveillance of HCC
A completed clinical trial evaluating non-contrast abbreviated MRI for secondary surveillance of hepatocellular carcinoma. The study is spon…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors [Phase 2]
This Phase 2 clinical trial is evaluating a three-drug combination (trametinib, everolimus, and lenvatinib) for recurrent/refractory advance…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: Palliative Hepatectomy Combined With Targeted Therapy and Immunotherapy for Advanced Hepatocellular Carcinoma [Phase 1]
An ongoing Phase 1 clinical trial is evaluating palliative hepatectomy combined with targeted therapy and immunotherapy for hepatocellular c…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Efficacy and Safety of HAIC in Combination With TQB2868 and Ramucirumab for Second-line Treatment of Advanced Hepatocellular Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of combining hepatic arterial infusion chemotherapy (HAIC) with TQB2868 and ramu…
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Cohort of Patients With Hepatocellular Carcinoma or Cholangiocarcinoma
A clinical trial is enrolling a cohort of patients with hepatocellular carcinoma or cholangiocarcinoma.
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Precision Treatment of Unresectable HCC Guided by Multi-omics Deep Learning Models [Phase 1]
A Phase 1 trial for unresectable hepatocellular carcinoma using multi-omics deep learning to guide precision therapy and is currently recrui…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Intra-Tumoral Vascular Growth Patterns is a Robust Indicator of Adjuvant Therapy Following Liver Resection in HCC
The trial explores intra-tumoral vascular growth patterns as a potential indicator to guide adjuvant therapy following liver resection for h…
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Atezolizumab/Bevacizumab Followed by On-demand TACE or Initial Synchronous Treatment With TACE and Atezolizumab/Bevacizumab [Phase 2]
Phase 2 trial assessing atezolizumab/bevacizumab followed by on-demand TACE or initial synchronous TACE with atezolizumab/bevacizumab for un…
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Multi-analyte Blood Test Clinical Trial
This clinical trial update notes that a multi-analyte blood test is currently recruiting for evaluation in patients with cirrhosis and hepat…
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CLINICAL_TRIALS research · 2024-06-13Clinical Trial Update: Combined TACE, TKI/Anti-VEGF and ICIs as Conversion Therapy for Advanced Hepatocellular Carcinoma
A clinical trial status update indicating recruitment for a study combining TACE, TKIs/anti-VEGF therapy, and immune checkpoint inhibitors a…
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CLINICAL_TRIALS research · 2024-06-10Clinical Trial Update: Compare the Accuracy of ctDNA-MRD and MVI Result in Predicting Postoperative Recurrence of Hepatocellular Carcinoma
A ClinicalTrials.gov entry for a study evaluating whether ctDNA-MRD and microvascular invasion can more accurately predict postoperative rec…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease. [Phase 3]
Phase 3 trial update announcing a study to evaluate zinc supplementation for improving prognosis in patients with compensated advanced chron…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Liver Cancer Disparities in American Indian and Alaska Native Persons [Phase 2]
This clinical trial update discusses a Phase 2 study investigating liver cancer disparities affecting American Indian and Alaska Native peop…
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CLINICAL_TRIALS research · 2024-05-31Clinical Trial Update: Huaier Granule for Prevention of Recurrence and Metastasis of Hepatocarcinoma Following Local Ablation
A clinical trial is recruiting to test Huaier Granule for preventing recurrence and metastasis of hepatocellular carcinoma after local ablat…
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CLINICAL_TRIALS research · 2024-05-31Clinical Trial Update: Comparison of Gd-EOB-DTPA-enhanced MRI and Contrast-enhanced Ultrasound for Measuring Tumor Size of Solitary Hepatocellular Carcinoma ≤ 5cm:A Retrospective Study
A retrospective study comparing Gd-EOB-DTPA-enhanced MRI and contrast-enhanced ultrasound for measuring the size of solitary hepatocellular …
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CLINICAL_TRIALS research · 2024-05-21Clinical Trial Update: PD-1/PD-L1 Inhibitors and Anti-angiogenic Therapy Combined With/Without TACE/HAIC in Patients With BCLC B/C Hepatocellular Carcinoma Beyond Up-to-7
This clinical trial update describes a study evaluating PD-1/PD-L1 inhibitors combined with anti-angiogenic therapy, with or without transar…
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: The Dual Impact of Cirrhosis on Transplantation for Hepatocellular Carcinoma：a Two-center Retrospective Cohort Study in China
A two-center retrospective cohort study from China examining how cirrhosis affects liver transplantation outcomes for hepatocellular carcino…