Hepatocellular Carcinoma
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CLINICAL_TRIALS research · 2024-09-05Clinical Trial Update: A Phase I Study of ERY974 in Patients With Hepatocellular Carcinoma [Phase 1]
Phase I clinical trial evaluating ERY974 in patients with hepatocellular carcinoma; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-09-03Clinical Trial Update: Postoperative Adjuvant Therapy of Donafenib for Hepatocellular Carcinoma [NA]
This clinical trial update notes ongoing recruitment for postoperative adjuvant therapy with donafenib in hepatocellular carcinoma.
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CLINICAL_TRIALS research · 2024-08-29Clinical Trial Update: Title of Manuscript: Development and Internal-external Validation of a Comprehensive Model for Predicting Risk of Post-RFA Recurrence in HCC Patients
A clinical study aims to develop and validate a model to predict post-RFA recurrence in hepatocellular carcinoma patients. The trial is curr…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies. [NA]
A multicenter Phase II basket trial at Zhejiang Cancer Hospital is evaluating hypofractionated radiotherapy or SBRT followed by immunotherap…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: Concurrently vs Sequentially Combined HAIC With Targeted and Immunotherapy in Potentially Resectable HCC [Phase 3]
A Phase 3 clinical trial registry entry examining concurrent versus sequential hepatic arterial infusion chemotherapy combined with targeted…
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Perioperative Risk of Immunotherapy Based Neoadjuvant and Conversion Therapy for Hepatocellular Carcinoma
This clinical trial assesses perioperative risks associated with immunotherapy-based neoadjuvant and conversion therapy for hepatocellular c…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Gut Microbiota in Liver Cancer (Treated With TKIs In Combination With ICIs) [Phase 2]
A Phase 2 study evaluating how gut microbiota might affect outcomes in liver cancer patients treated with a combination of tyrosine kinase i…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Intra-tumor Injection of Drug-eluting Microspheres With Multiple Drugs [Phase 2]
Phase 2 clinical trial update for intra-tumor injection of drug-eluting microspheres delivering multiple drugs in hepatocellular carcinoma; …
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Single Arm Clinical Trial (Gut Microbiota and HCC) [Phase 2]
Phase 2 single-arm clinical trial investigating the relationship between gut microbiota and hepatocellular carcinoma. The study status is no…
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CLINICAL_TRIALS research · 2024-08-20Clinical Trial Update: Triple Therapy Sequential Radiotherapy in Unresectable HCC (TALENP003)
ClinicalTrials.gov entry TALENP003 describes a trial of triple therapy sequential radiotherapy for unresectable hepatocellular carcinoma, cu…
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: CT011 Autologous CAR-T Cells in Patients With Hepatocellular Carcinoma at Risk of Recurrence After Surgical Resection [Phase 1]
Phase 1 clinical trial evaluating CT011 autologous CAR-T cells for hepatocellular carcinoma in patients at risk of recurrence after surgical…
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Application of Perioperative Remote Ischemic Conditioning in Patients Undergoing Hepatectomy [NA]
This document reports a completed clinical trial evaluating perioperative remote ischemic conditioning in patients undergoing hepatectomy fo…
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Image Driven Hepatocellular Carcinoma Invasiveness Evaluation Research
This document provides a clinical trial update for an image-driven study evaluating invasiveness in hepatocellular carcinoma (stage III). Th…
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CLINICAL_TRIALS research · 2024-08-16Clinical Trial Update: a Cohort Study (Gut Microbiota and HCC)
A cohort study examining the relationship between gut microbiota and hepatocellular carcinoma is in planning and not yet recruiting. Sponsor…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: Comprehensive Prognostic Model: The Study Introduces a Novel Prognostic Model That Incorporates a Wide Range of Clinical and Laboratory Variables, Providing a More Holistic Approach to Predicting Overall Survival in HCC Patients
A clinical trial update presents a novel prognostic model that integrates diverse clinical and laboratory variables to predict overall survi…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: Ablation of Oligometastasis Combined With Lenvatinib and PD-1 Inhibitor for Advanced Hepatocellular Carcinoma [NA]
Clinical trial assessing the combination of ablation of oligometastasis, lenvatinib, and a PD-1 inhibitor for advanced hepatocellular carcin…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: Safety and Efficacy of Autologous Tumor-infiltrating Lymphocytes Therapy in Patients With Hepatocellular Carcinoma [Phase 1, Phase 2]
This entry notes a phase 1/2 clinical trial evaluating autologous tumor-infiltrating lymphocytes therapy for hepatocellular carcinoma, curre…
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CLINICAL_TRIALS research · 2024-08-12Clinical Trial Update: Find HDV and Determine Its Status in Turkey
A Turkish clinical trial is currently recruiting to Find HDV and determine its status, focusing on hepatitis D infection and related liver c…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: A Study of Camrelizumab Plus Apatinib as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Radical Resection or Ablation [Phase 2]
Phase 2 clinical trial evaluating camrelizumab plus apatinib as adjuvant therapy for hepatocellular carcinoma at high risk of recurrence aft…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: bTAE-HAIC Combined With Lenvatinib and Sintilimab for Infiltrative Hepatocellular Carcinoma [NA]
A clinical trial is evaluating the combination of bTAE-HAIC with Lenvatinib and Sintilimab for infiltrative hepatocellular carcinoma, with r…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Early-stage Detection of Liver Cancer by Proteins in Peripheral Blood
A clinical trial investigates early detection of Hepatocellular Carcinoma using protein markers in peripheral blood; the current status of t…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Icaritin Soft Capsule Versus Huachansu Tablet in the First-line Treatment of Unresectable Hepatocellular Carcinoma With Poor Conditions and Biomarker Enrichment (Biomarker Enrichment Study of Poor Prognosis HCC Patients, BESTPOP) [Phase 3]
Phase 3 randomized trial comparing Icaritin Soft Capsule versus Huachansu Tablet as first-line therapy for unresectable hepatocellular carci…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Transfemoral Versus Transradial Approach in Transarterial Chemoembolization of Hepatocellular Carcinoma
A clinical trial evaluating transfemoral versus transradial arterial access for transarterial chemoembolization in hepatocellular carcinoma,…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Prospective Real-World Study of HAIC With Raltitrexed or 5-Fluorouracil for the Treatment of Hepatocellular Carcinoma [NA]
The registry entry describes an ongoing prospective real-world study evaluating hepatic arterial infusion chemotherapy with raltitrexed or 5…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: SBRT Combined With Adbelimumab and Apatinib for Perioperative and Conversion Therapy of Hepatocellular Carcinoma [Phase 2]
This Phase 2 clinical trial update explores combining SBRT with Adbelimumab and Apatinib for perioperative and conversion therapy in hepatoc…