Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Combination of SFRT, PD-L1 Inhibitor, and Anti-VEGF in Advanced Hepatocellular Carcinoma [NA]
This study evaluates a combination of spatially fractionated radiotherapy, a PD-1 inhibitor, and anti-VEGF therapy for advanced hepatocellul…
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CLINICAL_TRIALS research · 2024-11-26Clinical Trial Update: Comparison of Serum Myokine Dosages and Imaging Methods in the Evaluation of Sarcopenia in Patients With Hepatocellular Carcinoma [NA]
A clinical trial evaluating serum myokine dosages and imaging methods to evaluate sarcopenia in patients with hepatocellular carcinoma, whic…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08) [Phase 1, Phase 2]
GI Innovation's GI-102 is being studied in a phase 1/2 trial as a single agent and in combination with pembrolizumab or trastuzumab deruxtec…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Clinical Study of SN301A Injection in the Treatment of Hepatocellular Carcinoma [EARLY_Phase 1]
This document reports an ongoing EARLY Phase 1 clinical trial evaluating SN301A Injection for hepatocellular carcinoma, sponsored by Shangha…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: The Diagnostic Efficacy and Lesion Detection Advantages of 18F-FDG PET/CT and Enhanced MRI in Hepatic Malignancies
This clinical trial update assesses the diagnostic performance of 18F-FDG PET/CT and enhanced MRI for detecting hepatic tumors, including he…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant [Phase 2]
A Phase 2 clinical trial evaluating the combination of durvalumab and tremelimumab for hepatocellular carcinoma in patients listed for liver…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: A Study of PTX-9908 Injection for Non-resectable HCC with TACE [Phase 1, Phase 2]
PTX-9908 Injection is in a Phase 1/2 study for non-resectable hepatocellular carcinoma in combination with transarterial chemoembolization (…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Construction of a Recurrence Risk Prediction Model for Liver Resection Based on Drug Sensitivity of Patient-derived Hepatocellular Carcinoma Organoid
A clinical trial aims to build a recurrence risk prediction model for hepatocellular carcinoma patients undergoing liver resection, using dr…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Rituximab Combined With Prior Therapy in Advanced Hepatocellular Carcinoma: Efficacy & Safety Study [Phase 2]
A Phase 2 trial evaluating rituximab in combination with prior therapy for advanced hepatocellular carcinoma is currently recruiting to asse…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Ten-Year Outcomes of Operable Solitary Hepatocellular Carcinoma Patients: Impact of Tumor Size Over 6.5 cm and Microvascular Invasion
This clinical trial examines ten-year outcomes for operable solitary hepatocellular carcinoma, evaluating the impact of tumor size over 6.5 …
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Intravascular Radiofrequency Ablation of Sympathetic Nerves for the Treatment of Hepatocellular Carcinoma [NA]
Recruitment is ongoing for a study evaluating intravascular radiofrequency ablation of sympathetic nerves as a treatment for hepatocellular …
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: Combination of SBRT and Immunotherapy in Small Hepatocellular Carcinoma (HSBRT2402) [Phase 2]
A Phase 2 clinical trial update exploring a combination of SBRT and immunotherapy for small hepatocellular carcinoma, currently recruiting (…
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: Safety and Efficacy of Degradable Microsphere in Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma [NA]
This is a clinical trial update evaluating the safety and efficacy of degradable microspheres used in transarterial chemoembolization for he…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Sequential T and I With H101 Via HAI for BCLC C Stage HCC: A Prospective Single-Center Single-Arm Pilot Study [Phase 2]
A prospective, single-center, single-arm Phase 2 pilot study evaluating sequential T and I with H101 delivered by hepatic arterial infusion …
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Goal-directed LCVP Based on HP in Laparoscopic Hepatectomy [NA]
The First Affiliated Hospital with Nanjing Medical University is conducting a clinical trial evaluating goal-directed LCVP based on HP in la…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Statin for Preventing Hepatocellular Carcinoma Recurrence After Curative Treatment [Phase 4]
Phase 4 clinical trial update evaluating whether statins can prevent recurrence of hepatocellular carcinoma after curative treatment; the st…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Radiofrequency Ablation Using Combined RF Energy Delivery Mode and Octopus Electrodes for Hepatocellular Carcinoma [NA]
This clinical trial update notes an ongoing study on hepatocellular carcinoma using a novel radiofrequency ablation approach with combined R…
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CLINICAL_TRIALS research · 2024-11-04Clinical Trial Update: A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 with Valganciclovir (VGCV) in Subjects with Hepatocellular Carcinoma [Phase 1, Phase 2]
This document provides an update on a phase 1/2 clinical trial evaluating RZ-001 with valganciclovir in hepatocellular carcinoma; the study …
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: TACE Combined With ICIs Plus MTT After 125I Irradiation Stent Placement in HCC With Main PVTT.
This clinical trial is evaluating a multi-modality treatment (TACE with immune checkpoint inhibitors and MTT after 125I irradiation stent pl…
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: Atezolizumab and BEvacizumab With STereotactic Body Radiotherapy for Advanced Hepatocellular Carcinoma [NA]
A ClinicalTrials.gov update describes a study of atezolizumab and bevacizumab with stereotactic body radiotherapy for advanced hepatocellula…
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CLINICAL_TRIALS research · 2024-10-30Clinical Trial Update: Sintilimab Combined SBRT As Neoadjuvant Therapy for Resectable HCC with PVTT [Phase 2]
A Phase 2 clinical trial is investigating sintilimab plus stereotactic body radiotherapy as neoadjuvant therapy for resectable hepatocellula…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: A Prototype AI Algorithm Versus Liver Imaging Reporting and Data System (LI-RADS) Criteria in Diagnosing HCC on CT [NA]
An ongoing clinical trial at The University of Hong Kong evaluating whether a prototype AI algorithm can diagnose hepatocellular carcinoma o…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: DEB-TACE Prior to Liver Transplantation in the Treatment of HCC [Phase 4]
Phase 4 clinical trial evaluating drug-eluting bead transarterial chemoembolization (DEB-TACE) prior to liver transplantation in patients wi…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: TIPS Plus Half-dose Donafenib in AHCC with PVTT-associated Portal Hypertension [Phase 2]
A Phase 2 clinical trial assessing TIPS plus half-dose donafenib with AHCC for hepatocellular carcinoma with PVTT and PVTT-associated portal…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: A Multicenter Prospective Observational Study of Computer-aided Risk Perception and Prognosis Prediction in the Whole Process of Laparoscopic Hepatobiliary and Pancreatic Surgery
This is an ongoing multicenter observational study evaluating computer-aided risk perception and prognosis prediction during laparoscopic he…