Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma [Phase 3]
A Phase 3 global trial is evaluating transarterial chemoembolization combined with durvalumab and bevacizumab for locoregional hepatocellula…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery
An observational study to evaluate how well a subsequent treatment works in adults with unresectable hepatocellular carcinoma after prior th…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Radioembolization Versus External Radiation Therapy [Phase 2]
A Phase 2 clinical trial is comparing radioembolization to external beam radiation therapy for hepatocellular carcinoma. The study is curren…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Impact of "Teaching the Teachers" Concept on Global Education and Application of Hepatocellular Carcinoma Diagnosis Guidelines
This clinical trial update discusses an MD Anderson Cancer Center study evaluating a 'Teaching the Teachers' concept to improve global educa…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Surveys, Blood Testing, and Fibroscan in Screening for Liver Fibrosis and Liver Cirrhosis [NA]
This update describes a study that uses surveys, blood testing, and FibroScan to screen for liver fibrosis and liver cirrhosis in patients w…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Pilot Study to Assess the Clinical Utility of PYLARIFY PET-CT for Detecting Metastasis in Pancreatic Cancer, Hepatocellular Carcinoma and Breast Cancer [Phase 1]
Phase 1 pilot study evaluating the clinical utility of Pylarify PET-CT for detecting metastasis in pancreatic cancer, hepatocellular carcino…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma [Phase 1]
Phase 1 trial evaluating autologous GPC3-targeted CAR T cells (RPCAR01) for advanced or metastatic hepatocellular carcinoma; the study statu…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: TACE Plus Camrelizumab and Apatinib for Unresectable Hepatocellular Carcinoma [Phase 3]
A Phase 3 study is recruiting to evaluate the combination of transarterial chemoembolization (TACE) with camrelizumab and apatinib in patien…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Can Aspirin Reduce the Risk of HCC in Cirrhosis: The AspiRe HCC Trial [Phase 3]
Phase 3 trial assessing whether aspirin can reduce the risk of hepatocellular carcinoma in patients with liver cirrhosis; the AspiRe HCC Tri…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206) [Phase 1, Phase 2]
A clinical trial evaluating the safety and tolerability of Pumitamig alone or in combination with ipilimumab in first-line advanced or unres…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of ZW251 in Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial update notes a study of ZW251 in participants with advanced solid tumors, including hepatocellular carcinoma, non-small c…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular Carcinoma [Phase 2]
This Phase 2 trial compares STRIDE (durvalumab plus tremelimumab) with lenvatinib versus STRIDE alone in unresectable hepatocellular carcino…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Single-cell Multiomics and Spatiotemporal Omics Analyze the Mechanism of Liver Degenerative Disease
A recruiting clinical study uses single-cell multiomics and spatiotemporal omics to investigate mechanisms of liver degeneration. Sponsored …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer [Phase 2]
This Phase 2 trial evaluates whether chemotherapy with atezolizumab is superior to chemotherapy with bevacizumab and atezolizumab in patient…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial [Phase 1, Phase 2]
A Phase 1/2 clinical trial (SAPHIRE) is evaluating adding sapanisertib to cabozantinib for advanced or metastatic hepatocellular carcinoma w…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Electronic Symptom Monitoring of Patient-Reported Outcomes Among Patients With Hepatocellular Carcinoma During Immunotherapy (PRIME-HCC): Protocol for a Randomised Controlled Trial [NA]
This document outlines the protocol for a randomized controlled trial evaluating electronic symptom monitoring of patient-reported outcomes …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Sequential FOLFOX-HAIC-TACE Plus Sintilimab-Bevacizumab Neoadjuvant Therapy Versus Direct Resection in Resectable High-Risk Recurrence Hepatocellular Carcinoma [Phase 1, Phase 2]
This clinical trial update outlines a Phase 1/2 study evaluating sequential FOLFOX-HAIC-TACE with sintilimab and bevacizumab as neoadjuvant …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: DNA Vaccine Therapy in Treating Patients With Chronic Hepatitis C Virus Infection [Phase 1]
This document reports a Phase 1 clinical trial evaluating a DNA vaccine therapy for chronic hepatitis C virus infection. The study is curren…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma [Phase 2]
The document provides a status update on a Phase 2 trial of Casdozokitug in combination with Toripalimab and Bevacizumab for unresectable/me…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma [Phase 1]
Phase 1 clinical trial update on QXL138AM assessing safety, pharmacokinetics, and preliminary efficacy in patients with solid tumors and mul…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the theranostic pair RYZ811 (diagnostic) and RYZ801 (therapeutic) for Glypican-3 positive unresectable…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Radiofrequency Ablation for Hepatocellular Carcinoma Using Octopus MP Electrodes
Clinical trial update on a study of radiofrequency ablation for hepatocellular carcinoma using Octopus MP electrodes; the trial is active bu…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy [Phase 1, Phase 2]
Clinical trial evaluating oral 7HP349 (Alintegimod) in combination with ipilimumab, followed by nivolumab monotherapy, in patients with adva…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) [Phase 2]
This Phase 2 MATCH Screening Trial update describes ongoing evaluation of targeted therapies matched to genetic alterations in patients with…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: TheraBionic P1 Device in Subjects With Advanced Hepatocellular Carcinoma [NA]
The update indicates that a trial evaluating the TheraBionic P1 Device for advanced/recurrent hepatocellular carcinoma is currently recruiti…