Hepatocellular Carcinoma

CLINICAL_TRIALS research · 2025-04-01

Clinical Trial Update: Tumor Antigen Discovery for Innovative Cancer Immunotherapies in HCC: from Benchside to Bedside (HepAnt)

This update outlines an ongoing clinical trial initiative in hepatocellular carcinoma focused on identifying tumor antigens to support innov…

CLINICAL_TRIALS research · 2025-04-01

Clinical Trial Update: TANGO-LIVER Three Arm Nuclear Growth Observation in Liver Surgery [NA]

A three-arm clinical trial called TANGO-LIVER is evaluating nuclear growth observation in liver surgery and is currently recruiting particip…

CLINICAL_TRIALS research · 2025-04-01

Clinical Trial Update: Efficacy and Safety of Sintilimab Combined With Lenvatinib and HAIC for Neoadjuvant Therapy of Borderline Resectable HCC [Phase 2]

This clinical trial update describes a Phase 2 study of sintilimab in combination with lenvatinib and hepatic arterial infusion chemotherapy…

CLINICAL_TRIALS research · 2025-03-30

Clinical Trial Update: TARGETed Therapy Drug MONITOring in DIGestive Oncology [NA]

UNICANCER-sponsored clinical trial is recruiting a targeted therapy monitoring study in digestive oncology, including metastatic colorectal …

CLINICAL_TRIALS research · 2025-03-28

Clinical Trial Update: Icariin Soft Capsules Combined With TACE as Adjuvant Therapy for HCC [Phase 2]

A Phase 2 clinical trial evaluating Icariin Soft Capsules in combination with Transarterial Chemoembolization as adjuvant therapy for hepato…

CLINICAL_TRIALS research · 2025-03-26

Clinical Trial Update: Durvalumab for Advanced Hepatocellular Carcinoma in Patients With Active Chronic Hepatitis B Virus Infection [Phase 2]

Durvalumab is being studied in a Phase 2 trial for advanced hepatocellular carcinoma in patients with active chronic hepatitis B infection. …

CLINICAL_TRIALS research · 2025-03-26

Clinical Trial Update: Biomarkers and Molecular Mechanism Study of Hepatocellular Carcinoma After Radical Resection and Conversion Therapy

A clinical study sponsored by Shanghai Zhongshan Hospital evaluating biomarkers and the molecular mechanisms of hepatocellular carcinoma aft…

CLINICAL_TRIALS research · 2025-03-26

Clinical Trial Update: Icaritin Soft Capsules+TACE+Immunotherapy+Targeted Therapy Versus TACE+Immunotherapy+Targeted Therapy for Unresectable Hepatocellular Carcinoma [Phase 1, Phase 2]

A Phase 1/2 clinical trial protocol evaluating the addition of Icaritin soft capsules to TACE plus immunotherapy and targeted therapy for un…

CLINICAL_TRIALS research · 2025-03-25

Clinical Trial Update: Retrospective Clinical Validation of HepatoPredict

Retrospective clinical validation study of HepatoPredict by Ophiomics, with hepatocellular carcinoma as the primary condition; the trial is …

CLINICAL_TRIALS research · 2025-03-25

Clinical Trial Update: Combined HAIC, TKI/Anti-VEGF and ICIs as Conversion Therapy for Unresectable Hepatocellular Carcinoma

This ClinicalTrials.gov entry outlines a study evaluating a combination approach using hepatic arterial infusion chemotherapy (HAIC), tyrosi…

CLINICAL_TRIALS research · 2025-03-24

Clinical Trial Update: Phase I Study of OriC902 in Treatment of Advanced HCC [Phase 1]

Phase I trial of OriC902 for advanced hepatocellular carcinoma is currently recruiting, sponsored by Peking University.

CLINICAL_TRIALS research · 2025-03-24

Clinical Trial Update: 4D-MRI for Precision Medicine

A clinical trial update shows that a study using 4D-MRI for precision medicine is currently recruiting, focusing on liver cancer and lung ca…

CLINICAL_TRIALS research · 2025-03-24

Clinical Trial Update: Immune Checkpoint Therapy vs Target Therapy in Reducing Serum HBsAg Levels in Patients With HBsAg+ Advanced Stage HCC [Phase 2]

A Phase 2 trial comparing immune checkpoint therapy with targeted therapy to reduce HBsAg levels in patients with HBsAg-positive advanced he…

CLINICAL_TRIALS research · 2025-03-21

Clinical Trial Update: CXD101 in Immunotherapy-related Liver Cancer [Phase 2]

Phase 2 clinical trial of CXD101 for hepatocellular carcinoma is currently recruiting.

CLINICAL_TRIALS research · 2025-03-20

Clinical Trial Update: HCC Innervation Assessment

A status update for trial NCT06886763 on hepatocellular carcinoma indicates the study is active but not recruiting, focusing on innervation …

CLINICAL_TRIALS research · 2025-03-19

Clinical Trial Update: An Exploratory Clinical Study on Neoadjuvant Treatment of Hepatocellular Carcinoma with QL1706 Combined with Lenvatinib [Phase 2]

An exploratory Phase 2 clinical trial evaluating neoadjuvant treatment of hepatocellular carcinoma with QL1706 in combination with lenvatini…

CLINICAL_TRIALS research · 2025-03-19

Clinical Trial Update: A Phase I Study of LXP1788 Injection with Advanced Solid Tumors. [Phase 1]

This Phase I trial is evaluating the safety and tolerability of LXP1788 Injection in adults with advanced solid tumors and is currently recr…

CLINICAL_TRIALS research · 2025-03-18

Clinical Trial Update: Immune Checkpoint Inhibitors and Anti-vascular Endothelial Growth Factor Antibody/tyrosine Kinase Inhibitors with or Without HAIC for Advanced HCC

A ClinicalTrials.gov entry describes a study evaluating immune checkpoint inhibitors with or without anti-VEGF antibody/tyrosine kinase inhi…

CLINICAL_TRIALS research · 2025-03-18

Clinical Trial Update: Immune Checkpoint Inhibitors and Anti-vascular Endothelial Growth Factor Antibody/tyrosine Kinase Inhibitors with or Without TACE for Advanced HCC with Vascular Invasions

Clinical trial update on combining immune checkpoint inhibitors with anti-VEGF antibody/tyrosine kinase inhibitors, with or without TACE, fo…

CLINICAL_TRIALS research · 2025-03-14

Clinical Trial Update: Regional Lymph Node Metastasis and Survival Outcomes in Advanced HCC

This document reports a clinical trial update on regional lymph node metastasis and survival outcomes in advanced hepatocellular carcinoma, …