Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: AFPᶜ³³²T in Advanced HCC [Phase 1]
Status update on Adaptimmune's AFP-C332T trial for advanced hepatocellular carcinoma, with the Phase 1 study currently active but not recrui…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Impact of Splenectomy on the Efficacy of Targeted Therapy and Immunotherapy in Unresectable HCC Patients With Cirrhotic Portal Hypertension
This clinical trial update notes a study evaluating whether splenectomy influences the effectiveness of targeted therapy and immunotherapy i…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Acceptance and Commitment Therapy (ACT-HBC) for the Improvement of Cancer Distress in Patients With Hepatobiliary Cancers [NA]
Mayo Clinic is recruiting for a study of Acceptance and Commitment Therapy for reducing cancer-related distress in patients with malignant h…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC) [Phase 2]
A Phase 2 clinical trial evaluating adverse events and changes in disease activity when Livmoniplimab is combined with Budigalimab in adults…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Autologous Neoantigen-Specific T-Cell Therapy for Advanced Hepatocellular Carcinoma [Phase 1, Phase 2]
Clinical trial update on an autologous neoantigen-specific T-cell therapy for advanced hepatocellular carcinoma; the Phase 1/2 study is curr…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Evaluation of SIRT Followed by Immunotherapy for Treatment of Hepatocellular Carcinoma With Portal Vein Thrombosis [Phase 2]
Phase 2 clinical trial evaluating selective internal radiation therapy (SIRT) followed by immunotherapy for non-resectable hepatocellular ca…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: TACE Combined With Lenvatinib and PD-1 Inhibitor for Ruptured Hepatocellular Carcinoma [NA]
A clinical trial update indicates a study evaluating transarterial chemoembolization (TACE) combined with lenvatinib and a PD-1 inhibitor fo…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: A Clinical Study Evaluating HAIC Combined With Iparomlimab and Tuvonralimab Injection Plus Bevacizumab in Patients With Initially Potentially Resectable Hepatocellular Carcinoma (ITBHaic Study) [Phase 2]
A Phase 2 trial evaluating a combination of hepatic arterial infusion chemotherapy with iparomlimab, tuvonralimab, and bevacizumab for initi…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Post-Radical Treatment Antiviral Strategies in HBV-Related Liver Cancer: Impact on Tumor Prognosis
A clinical trial update describing post-radical treatment antiviral strategies for HBV-related hepatocellular carcinoma and their potential …
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection [NA]
This clinical trial is evaluating CT-guided localization for micro hepatocellular carcinoma before surgical resection. The study is currentl…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: ProspEXPO : Study of the Associations Between Hepatocellular Carcinoma and Chemical and Psychosocial Environmental EXPOsome [NA]
A clinical trial called ProspEXPO investigates associations between hepatocellular carcinoma and chemical and psychosocial environmental exp…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events [NA]
A clinical trial at MD Anderson Cancer Center is evaluating enhanced outpatient symptom management to reduce acute care visits caused by che…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: A Prospective Observational Cohort Study on Dynamic CD8+ T-cell Profiling and Multi-omics Biomarkers for Predicting Conversion Therapy Response in Unresectable Hepatocellular Carcinoma
This clinical trial update describes a prospective observational cohort in unresectable hepatocellular carcinoma to profile dynamic CD8+ T c…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: AHCC® as Immune Modulator in Cancer Patients Treated With Immunotherapy [NA]
Clinical trial update assessing AHCC as an immune modulator in cancer patients treated with immunotherapy; the study status is not yet recru…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: A Single-center, Single-arm, Phase II Clinical Study of Iparomlimab and Tuvonralimab Injection Combined With Regorafenib in the Treatment of Advanced Second-line or Above Hepatocellular Carcinoma [NA]
A single-center, single-arm Phase II study evaluating a combination of Iparomlimab and Tuvonralimab with Regorafenib for advanced second-lin…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: A Study of Valemetostat Tosylate (DS-3201b) With Atezolizumab and Bevacizumab in HCC [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating valemetostat tosylate (DS-3201b) in combination with atezolizumab and bevacizumab for hepatocellular car…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: To Test Whether Time-restricted Eating Coupled With a Healthy Diet is Beneficial in Liver Cancer Patients [NA]
This ClinicalTrials.gov update indicates a study evaluating whether time-restricted eating plus a healthy diet benefits adults with liver ca…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Development and Prospective Validation of a Heterogeneous Treatment Effect-Based Decision Model for Transarterial Chemoembolization Combined With or Without Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma [NA]
This clinical trial update describes the development and prospective validation of a heterogeneous treatment effect-based decision model for…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Fecal Microbiota Transfer in Liver Cancer to Overcome Resistance to Atezolizumab/Bevacizumab (FLORA) [Phase 2]
A Phase 2 clinical trial (FLORA) is evaluating fecal microbiota transfer to overcome resistance to atezolizumab/bevacizumab in hepatocellula…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Predictors of HCC in Post-HCV Cirrhotic Patients After SVR
This clinical trial aims to identify predictors of hepatocellular carcinoma in patients with HCV-related cirrhosis who achieved sustained vi…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: CEUS vs. AMRI for HCC Detection in Patients With Indeterminate Liver Nodules [NA]
A clinical trial comparing contrast-enhanced ultrasound (CEUS) with AMRI for detecting hepatocellular carcinoma in patients with indetermina…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Microbiota Modification for Immuno-oncology in Hepatocellular Carcinoma [Phase 2]
This Phase 2 clinical trial update describes microbiota modification as a strategy to enhance immuno-oncology in hepatocellular carcinoma, a…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: 90Y Transarterial Radioembolization Versus Microwave Ablation in Small Hepatocellular Carcinoma With Hypoalbuminemia [NA]
A clinical trial comparing Y-90 transarterial radioembolization versus microwave ablation for small hepatocellular carcinoma in patients wit…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: 29-Gene Liver Cancer Subtype and Immunotherapy Effectiveness
This clinical trial update describes a study on a 29-gene liver cancer subtype and immunotherapy in hepatocellular carcinoma, which is not y…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: An Exploratory Study on Developing an Integrated Approach Combining Multimodal Imaging and Multi-omics Characterization of Tumor Heterogeneity for Precision Diagnosis and Treatment Optimization in Liver Cancer.
This clinical trial update describes an exploratory study at Peking Union Medical College Hospital. It aims to integrate multimodal imaging …