Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: SIRT With Tremelimumab and Durvalumab for Resectable HCC [Phase 1]
Phase 1 clinical trial evaluating the combination of selective internal radiation therapy (SIRT) with tremelimumab and durvalumab for resect…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: A Phase II Single-Arm Study of Iparomlimab and Tuvonralimab (QL1706) in Combination With Lenvatinib and TACE for Advanced Hepatocellular Carcinoma [Phase 2]
Phase II single-arm study of Iparomlimab and Tuvonralimab (QL1706) in combination with lenvatinib and transarterial chemoembolization for ad…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: The Treatment of Liver Injury After Liver Resection With Polyene Phosphatidylcholine [Phase 4]
A Phase 4 clinical trial is evaluating polyene phosphatidylcholine for liver injury after liver resection; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: The Role of Serum AKR1B10 in Early Warning of Hepatocellular Carcinoma in Cirrhosis Patients
A clinical trial is evaluating whether serum AKR1B10 can serve as an early biomarker to warn of hepatocellular carcinoma in patients with ci…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Efficacy and Safety of Multimodal Ablation Combined With PD-1 Monoclonal Antibody, Lenvatinib and TACE in the Treatment of Unresectable Primary Hepatocellular Carcinoma: A Single-Arm, Single-Center Clinical Study [NA]
This is a single-arm, single-center clinical study evaluating multimodal ablation in combination with a PD-1 monoclonal antibody, lenvatinib…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Psychoeducational Intervention for Patients With Hepatocellular Carcinoma [NA]
This ClinicalTrials.gov update reports an ongoing trial at Massachusetts General Hospital evaluating a psychoeducational intervention for he…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Lparomlimab and Tuvonralimab Injection in Combination With TACE and Lenvatinib in the Treatment of Second-Line Therapy for Unresectable Intermediate-to-Advanced Hepatocellular Carcinoma [Phase 2]
A Phase 2 trial evaluating Lparomlimab and Tuvonralimab in combination with TACE and lenvatinib as second-line therapy for unresectable inte…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: A Two-Arm, Multicenter, Non-Randomized Controlled Study on the Efficacy of Yttrium-90 (Selective Internal Radiation Therapy) Therapy and Hepatic Arterial Infusion Chemotherapy (Hepatic Artery Infusion Chemotherapy) for Potentially Resectable Intermediate and Advanced Hepatocellular Carcinoma [NA]
A two-arm, multicenter, non-randomized study evaluating Yttrium-90 selective internal radiation therapy and hepatic arterial infusion chemot…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Evaluation Of Liver Resection Using Harmonic Scalpel Versus Cavitron Ultrasonic Surgical Aspirator (CUSA). [NA]
A clinical trial evaluating the Harmonic Scalpel versus Cavitron Ultrasonic Surgical Aspirator (CUSA) for liver resection, assessing safety …
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: The Impact of Emotional Stress on Immunotherapy Outcomes in Liver Cancer Patients: A Multi-Cohort Study
A multi-cohort study in hepatocellular carcinoma investigates whether emotional stress affects outcomes of immunotherapy with immune checkpo…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Effect and Mechanism of ALPPS Operation on Liver Regeneration
This clinical trial update describes evaluating the effects and mechanisms of the ALPPS liver surgery on liver regeneration in patients with…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Study of AU409 Capsule in Advanced Hepatocellular Carcinoma Patients Who Failed Standard Treatment [Phase 1]
Phase 1 clinical trial update for AU409 Capsule in patients with advanced hepatocellular carcinoma who failed standard therapy; the study is…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: A Phase II, Single-Arm, Prospective Trial on the Efficacy and Safety of QL1706 Combination Regimen as Second-Line Therapy for Targeted-Immunotherapy-Resistant Hepatocellular Carcinoma [Phase 2]
Phase II, single-arm trial evaluating the efficacy and safety of QL1706 in a targeted-immunotherapy-resistant hepatocellular carcinoma setti…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: A Study of BL-B01D1 Combined With Lenvatinib in Patients With Advanced Hepatocellular Carcinoma [Phase 2]
A Phase 2 trial evaluating BL-B01D1 in combination with lenvatinib for advanced hepatocellular carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: A Single-Arm, Multicenter, Exploratory Clinical Study of TACE Combined With Iparomlimab and Tuvonralimab Injection (QL1706) and Lenvatinib for Perioperative Treatment of Resectable Hepatocellular Carcinoma [Phase 2]
Phase 2, single-arm multicenter exploratory study evaluating perioperative TACE with iparomlimab, tuvonralimab (QL1706), and lenvatinib for …
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Efficacy & Safety of Anticoagulants in Cirrhosis ± HCC [Phase 4]
A Phase 4 clinical trial is evaluating the efficacy and safety of anticoagulants in patients with cirrhosis, with or without hepatocellular …
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Advanced Liver Cancer [Phase 1]
A Phase 1 clinical trial evaluating tumor-infiltrating lymphocyte immunotherapy for patients with advanced hepatocellular carcinoma is curre…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Role of Long Noncoding RNA LINC01134 in Metastasis of Hepatitis C Virus-related Hepatocellular Carcinoma
The clinical trial evaluates the role of the long noncoding RNA LINC01134 in metastasis of hepatitis C virus-related hepatocellular carcinom…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial update on cabozantinib alone or with atezolizumab for locally advanced or metastatic solid tumors; the study lists mu…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Tauroursodeoxycholic Acid (TUDCA) Plus Camrelizumab and Regorafenib in Hepatocellular Carcinoma Previously Treated With Anti-PD1/PD-L1 and Bevacizumab [Phase 2]
A Phase 2 clinical trial is evaluating Tauroursodeoxycholic acid (TUDCA) in combination with camrelizumab and regorafenib for hepatocellular…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: A Single-Arm, Multicenter, Exploratory Clinical Study of Transarterial Chemoembolization (TACE) Combined With Iparomlimab and Tuvonralimab Injection and Bevacizumab Injection for the Treatment of Unresectable, Non-Metastatic Hepatocellular Carcinoma (HCC) [Phase 2]
A Phase 2 single-arm exploratory trial assessing the combination of transarterial chemoembolization with iparomlimab, tuvonralimab, and beva…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: TACE Combined With Anti-PD-1 Antibody in Patients With Advanced Hepatocellular Carcinoma: Study on Efficacy and Immune Microenvironment
Clinical trial assessing the combination of transarterial chemoembolization (TACE) with an anti-PD-1 antibody for advanced hepatocellular ca…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC) [Phase 2, Phase 3]
This document reports a Phase 2/3 clinical trial evaluating the combination of Livmoniplimab and Budigalimab in adults with hepatocellular c…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Dissection of the Molecular and Immunological Interaction in Patients With HCC of Viral and Non-viral Etiologies
A clinical trial studying molecular and immunological factors in hepatocellular carcinoma arising from viral and non-viral etiologies is act…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Retrospective Study of Long-Term Survival of "Immuncell-LC" in Patients Undergoing Curative Resection for HCC in Korea
A retrospective study update assessing long-term survival outcomes in hepatocellular carcinoma patients who underwent curative resection and…