Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Survival Analysis of Surgical Resection Versus Observation in Patients With Initially uHCC Achieving CR After Systemic Therapy
This clinical trial update describes an ongoing study comparing surgical resection versus observation for patients with initially unresectab…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Predictors and Outcome of Rupture HCC in AU Hospitals
Assiut University is conducting a clinical trial to identify predictors and outcomes of ruptured hepatocellular carcinoma in Assiut Universi…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Glypican-3 as a Prognostic Factor in Patients With Hepatocellular Carcinoma Treated by Immunotherapy
A clinical trial is evaluating glypican-3 as a prognostic factor in hepatocellular carcinoma patients treated with immunotherapy and is curr…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Camrelizumab and Apatinib With or Without FOLFOX Chemotherapy for Advanced HCC [Phase 3]
A Phase 3 clinical trial is investigating camrelizumab and apatinib with or without FOLFOX chemotherapy for advanced hepatocellular carcinom…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: HOPE Against Cancer Recurrence in HCC [Phase 4]
Phase 4 clinical trial update for HOPE Against Cancer Recurrence in hepatocellular carcinoma; the study is currently recruiting under sponso…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Safety and Efficacy of Paclitaxel Liposome Arterial Infusion Combined With Systemic Therapy for Second-Line Treatment of Advanced Liver Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the safety and efficacy of paclitaxel liposome delivered via arterial infusion combined with systemic th…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Clinical Trial of Autologous CD19 CAR-T Cells (CNCT19) Therapy for Advanced Hepatocellular Carcinoma [Phase 1]
A Phase 1 clinical trial evaluating autologous CD19 CAR-T CNCT19 therapy for advanced hepatocellular carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Transarterial Chemoembolization With Low-Dose Bevacizumab Plus Atezolizumab as First-Line Treatment for Unresectable Hepatocellular Carcinoma [NA]
A clinical trial update outlines a planned first-line regimen for unresectable hepatocellular carcinoma using transarterial chemoembolizatio…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: A Study of TACE Combined With Camrelizumab Plus Rivoceranib (Apatinib) in Patients With Incurable Hepatocellular Carcinoma [Phase 3]
A Phase 3 trial evaluating TACE combined with camrelizumab and rivoceranib (apatinib) for incurable hepatocellular carcinoma is currently ac…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Intravital Microscopy in Human Solid Tumors [NA]
Mayo Clinic is conducting a clinical trial using intravital microscopy in multiple solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Fecal Microbiota Transplantation to RESCUE Patients With Unresectable Hcc Progressors to First Line Therapy With AtezolizUmaB and Bevacizumab [Phase 2]
A Phase 2 trial is evaluating fecal microbiota transplantation in patients with unresectable hepatocellular carcinoma who progress on first-…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: SBRT Plus Systemic Therapy vs Systemic Therapy Alone in BCLC C Hepatocellular Carcinoma [Phase 2]
This Phase 2 clinical trial evaluates adding SBRT to systemic therapy versus systemic therapy alone for hepatocellular carcinoma with BCLC s…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Mutational Landscape in Hepatocellular Carcinoma
This clinical trial update summarizes the mutational landscape of hepatocellular carcinoma based on genomic profiling from the completed stu…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: A Cell-free tsRNA Signature for Early Detection of Hepatocellular Carcinoma
A clinical trial at City of Hope Medical Center is evaluating a cell-free tsRNA signature as a potential biomarker for early detection of he…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: The Effectiveness and Safety in High-risk Patients Receiving First-line Atezolizumab and Bevacizumab Combined With HAIC for HCC: a Retrospective Study [NA]
A retrospective study evaluating the effectiveness and safety of first-line Atezolizumab plus Bevacizumab combined with HAIC in high-risk he…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Identification of an Immune Single Cell Transcriptomic Profile of Responder and Non-responder Hepatocellular Carcinoma Patients Treated With Immune-checkpoint Inhibitors
A clinical trial is investigating an immune single-cell transcriptomic profile associated with response to immune-checkpoint inhibitors in h…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Phase III Study of Toripalimab（JS001） Combined With Lenvatinib for Advanced HCC [Phase 3]
This entry reports a Phase III trial evaluating toripalimab in combination with lenvatinib for advanced hepatocellular carcinoma, which is c…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: New Diagnostic Criteria in the Evaluation Response to Ablation Treatment of Hepatocellular Carcinoma Nodules
This clinical trial is evaluating new diagnostic criteria for assessing response to ablation therapy in hepatocellular carcinoma nodules.
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Understanding Gene ENvironment Interaction in ALcohol-related Hepatocellular Carcinoma [NA]
Clinical trial update for NCT07272200 investigating gene-environment interactions in alcohol-related hepatocellular carcinoma; recruitment i…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Trop2-targeted immunoPET Imaging of Solid Tumors [Phase 2, Phase 3]
Clinical trial update for Trop2-targeted immunoPET imaging of solid tumors, currently in Phase 2/3 and recruiting.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Study Assessing PET Imaging With Zirconium-labelled Girentuximab in Patients With HCC, ICC or NEN [NA]
A clinical trial is evaluating PET imaging with zirconium-labelled girentuximab in patients with hepatocellular carcinoma, intrahepatic chol…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Durvalumab With/Without Tremelimumab After Palliative Hypofractionated Radiotherapy for Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial evaluating durvalumab with or without tremelimumab after palliative hypofractionated radiotherapy for hepatocellular …
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: T-Cell Therapy (ECT204) in Adults With Advanced HCC [Phase 1, Phase 2]
A Phase 1/2 trial of the T-cell therapy ECT204 for adults with advanced hepatocellular carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer [Phase 1]
Phase 1 trial evaluating the combination of guadecitabine and durvalumab in advanced cholangiocarcinoma, gallbladder cancer, hepatocellular …
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program [Phase 2]
Phase 2 trial evaluating in-home versus in-clinic subcutaneous nivolumab administration under the CC Beyond Walls program; the study is curr…