Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Phase IIb Study of AST-3424 in Patients With AKR1C3-high Expressing Advanced Hepatocellular Carcinoma [Phase 2]
Phase IIb study of AST-3424 in AKR1C3-high expressing advanced hepatocellular carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: A Study to Evaluate Camrelizumab Plus Rivoceranib (Apatinib) as Adjuvant Therapy in Patients With Hepatocellular Carcinoma (HCC) at High Risk of Recurrence After Curative Resection or Ablation [Phase 3]
Phase 3 trial evaluating camrelizumab plus apatinib (rivoceranib) as adjuvant therapy for hepatocellular carcinoma at high risk of recurrenc…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: A Phase III Randomized Study of TACE Plus an Oral Triple-Agent Cocktail Versus TACE Plus First-Line Targeted Immunotherapy in Unresectable Hepatocellular Carcinoma [Phase 2, Phase 3]
This clinical trial update describes a Phase II/III randomized study comparing TACE plus an oral triple-agent cocktail versus TACE plus firs…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Durvalumab and Tremelimumab With Lenvatinib as First-line Treatment in Patients With Unresectable Hepatocellular Carcinoma [Phase 2]
Phase 2 trial update evaluating first-line durvalumab and tremelimumab in combination with lenvatinib for unresectable hepatocellular carcin…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Survey of Cabozantinib Tablets Used To Treat People With Hepatocellular Carcinoma
Clinical trial update describing a survey of cabozantinib tablets used to treat hepatocellular carcinoma, sponsored by Takeda, with the stud…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: The Efficacy of Preoperative Oral Administration of Lactobacillus Reuteri Combined With Preoperative Neoadjuvant/Conversion Immunotherapy in Patients With Primary Resectable Liver Cancer [NA]
A clinical trial investigating preoperative Lactobacillus reuteri with neoadjuvant immunotherapy for primary resectable hepatocellular carci…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform
An observational basket trial sponsored by Elephas aims to collect tissue to develop and train a live tumor diagnostic platform across multi…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90
This clinical trial update indicates a study on using liquid biopsy to characterize hepatocellular carcinoma after Yttrium-90 therapy and is…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: A Study Comparing Immunotherapy Alone Versus Immunotherapy Combined With Radiotherapy in Patients With Hepatocellular Carcinoma (HCC) With Vascular Invasion [Phase 2]
Phase 2 clinical trial evaluating immunotherapy alone versus immunotherapy plus radiotherapy in patients with hepatocellular carcinoma with …
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Downstaging Unresectable Hepatocellular Carcinoma to Resectable Disease With Combined Immunotherapy and Stereotactic Beamed Radiotherapy: a Pilot Study [NA]
A pilot study investigates downstaging unresectable hepatocellular carcinoma to resectable disease using a combination of immunotherapy and …
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Observational Study Protocol: LIVER-R
An observational study protocol called LIVER-R sponsored by AstraZeneca focusing on hepatobiliary cancers, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: vGRID SBRT: A Phase I Clinical Trial in Unresectable or Metastatic HCC [NA]
Phase I clinical trial evaluating vGRID SBRT for unresectable or metastatic hepatocellular carcinoma, currently recruiting at University of …
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Neoadjuvant Hypofractionated Stereotactic Body Radiation Therapy Prior to Surgery for Hepatocellular Carcinoma: a Feasibility Study. [Phase 1]
Phase 1 feasibility study assessing neoadjuvant hypofractionated stereotactic body radiotherapy before surgery for hepatocellular carcinoma;…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Characterization of Focal Liver Lesions by Real-time Contrast-enhanced Ultrasound Imaging (CEUS) [NA]
A completed study evaluating real-time contrast-enhanced ultrasound for characterizing focal liver lesions, including liver cancer and cirrh…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: A Phase I Trial of IMA970A Plus Montanide in Combination With Durvalumab (Anti-PD-L1) [Phase 1]
A Phase I trial evaluating IMA970A plus Montanide in combination with durvalumab (anti-PD-L1) for hepatocellular carcinoma is currently acti…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas [Phase 2]
A Phase 2 clinical trial update describes a program for in-home cancer treatment with remote expert support, currently recruiting for patien…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery [Phase 3]
This Phase 3 clinical trial update describes a study evaluating cisplatin-based chemotherapy after surgery for children and young adults wit…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Prediction of Decompensation and HCC Development in Advanced Chronic Liver Disease
A clinical trial registry entry from University Hospital Muenster outlining a study to predict decompensation and hepatocellular carcinoma d…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: TITAN-HCC: Neoadjuvant and Adjuvant QL1706 With TACE in Resectable Hepatocellular Carcinoma Beyond Milan Criteria [NA]
This entry reports a clinical trial (TITAN-HCC) evaluating QL1706 with transarterial chemoembolization (TACE) as neoadjuvant and adjuvant th…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Contrast-enhanced MRI in Detecting Benign and Malignant Liver Lesions [NA]
Clinical trial update for contrast-enhanced MRI to detect benign and malignant liver lesions; the study is currently active but not recruiti…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: NIR-II Fluorescence-Guided Hepatectomy Using ICG-Cisplatin Nanoprobes for HCC [EARLY_Phase 1]
A Phase 1 clinical trial is investigating NIR-II fluorescence-guided hepatectomy using ICG-Cisplatin nanoprobes for hepatocellular carcinoma…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: A Comparative Study of MRI and Ultrasound for Detection of Primary Hepatocellular Carcinoma, Body Composition and Risk Factors for Decompensation in Liver Cirrhosis
A clinical trial update describing an ongoing study comparing MRI and ultrasound for detecting primary hepatocellular carcinoma and evaluati…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Diagnostic Accuracy of Folate-Targeted NIR-II Carbon Dots for Ex Vivo HCC Detection
A clinical trial evaluating the diagnostic accuracy of folate-targeted NIR-II carbon dots for detecting hepatocellular carcinoma in ex vivo …
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Multimodal Deep Learning for Postoperative Liver Cancer Risk Stratification and Intervention [Phase 1, Phase 2]
Update on a Phase 1/2 clinical trial evaluating a multimodal deep learning approach to risk stratification and intervention following hepato…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: JMT106 Injection in the Treatment of Advanced Solid Tumors [Phase 1]
Phase 1 trial evaluating JMT106 injection for advanced solid tumors, including lung squamous cell carcinoma and hepatocellular carcinoma, is…