Hepatocellular Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating cabozantinib plus durvalumab with or without tremelimumab in patients with gastroesophageal cancer and o…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Nanocrystalline Megestrol Acetate for Cachectic Stage Locally Advanced Hepatocellular Carcinoma [Phase 3]
A Phase 3 clinical trial update for nanocrystalline Megestrol Acetate aimed at treating cachexia in patients with stage locally advanced hep…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: A Study to Evaluate Safety and Efficacy of Armored CAR-T Cell Injection C-CAR031 in Advanced Hepatocellular Carcinoma [Phase 1]
A Phase 1 clinical trial evaluating the safety and potential efficacy of the armored CAR-T cell therapy C-CAR031 in advanced hepatocellular …
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Preliminary Evaluation of Clinical Application of SPECT Imaging Targeting GPC3 [NA]
A preliminary evaluation of a SPECT-CT imaging approach targeting GPC3 for hepatocellular carcinoma, currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: TACE Combined With Tislelizumab, Lenvatinib, and Carvedilol for Unresectable HCC With Cirrhotic Portal Hypertension [Phase 2]
Phase 2 clinical trial evaluating transarterial chemoembolization plus tislelizumab, lenvatinib, and carvedilol for unresectable hepatocellu…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: FAD Subtype-Guided Combination Therapy for Unresectable Hepatocellular Carcinoma [Phase 2]
Phase 2 clinical trial update for a FAD subtype-guided combination therapy in unresectable hepatocellular carcinoma; the study is not yet re…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Predictive Value of Minimal Residual Disease for Postoperative Recurrence and Adjuvant PD-1 Inhibitor in HCC [NA]
Clinical trial NCT07350824 evaluates whether minimal residual disease can predict postoperative recurrence in hepatocellular carcinoma and a…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400 [Phase 1]
Phase 1 study assessing adverse events and change in disease activity in adults with select advanced solid tumors treated with ABBV-400; the…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Head to Head, Prospective, Open Label Multicenter Study on the Diagnostic Efficacy of GPC3 Targeted PET Imaging and Enhanced Magnetic Resonance Imaging for Hepatocellular Carcinoma [EARLY_Phase 1]
This early-phase, multicenter trial is evaluating the diagnostic performance of a GPC3-targeted PET radiotracer in combination with enhanced…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: A Phase II Trial of Organoid Drug Sensitivity Testing to Guide Therapy in Unresectable Hepatocellular Carcinoma [Phase 2]
This update describes a Phase II clinical trial using organoid drug sensitivity testing to guide therapy in patients with unresectable hepat…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Universal CAR-T Cells (REVO-UWD-03) for Advanced Hepatocellular Carcinoma and Lung Cancer [EARLY_Phase 1]
Early-phase clinical trial update for universal CAR-T cells REVO-UWD-03 in advanced hepatocellular carcinoma and non-small cell lung cancer,…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Sintilimab Plus Bevacizumab Biosimilar as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating sintilimab plus a bevacizumab biosimilar as neoadjuvant therapy for resectable hepatocellular carcinoma; recruitmen…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Collection of Tissue & Blood From Patients w/ Benign & Malignant Tumors of the Soft Tissue & Gastrointestinal Tract
This clinical trial update describes the collection of tissue and blood from patients with benign and malignant tumors of the soft tissue an…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Hepatobiliary and Pancreatic Tumor Biobank
Clinical trial update describing a hepatobiliary and pancreatic tumor biobank study led by Zhejiang University, currently not recruiting.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax [Phase 1]
Phase I trial updates the use of Tumor Treating Fields in combination with cabozantinib or with pembrolizumab and nab-paclitaxel for various…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Conversion or Neoadjuvant Therapy in Hepatocellular Carcinoma
A ClinicalTrials.gov entry describes a study on conversion or neoadjuvant therapy for hepatocellular carcinoma, and the trial is currently r…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: TACE Versus HAIC, Combined With PD-1 Inhibitors and Lenvatinib for Unresectable Hepatocellular Carcinoma
A clinical trial comparing transarterial chemoembolization and hepatic arterial infusion chemotherapy, each combined with PD-1 inhibitors an…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: SARS-CoV-2 mRNA Vaccination in Patients With Hepatocellular Carcinoma Treated With Immune Checkpoint Inhibitors
A clinical trial exploring SARS-CoV-2 mRNA vaccination in patients with hepatocellular carcinoma undergoing treatment with immune checkpoint…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: naVIGation Invitations Liver surveillANce upTake
Imperial College London reports an updated clinical trial investigating uptake of liver surveillance in patients with hepatocellular carcino…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: QL1706 in Combination With Bevacizumab and RALOX HAIC for Hepatocellular Carcinoma With Vp3/4 PVTT [Phase 2]
A Phase 2 clinical trial evaluating QL1706 in combination with Bevacizumab and RALOX-HAIC for hepatocellular carcinoma with portal vein tumo…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Trial of Behavioral Intervention on Prognostic Survival of Patients With Unresectable Liver Cancer [NA]
A clinical trial is evaluating a behavioral intervention aimed at prognostic survival in patients with unresectable liver cancer, including …
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Efficacy and Safety of Icaritin Combined With mFOLFOX in Postoperative HCC With High-risk Recurrence Factors [Phase 2]
This document notes a Phase 2 clinical trial evaluating the efficacy and safety of adding icaritin to the mFOLFOX chemotherapy regimen for p…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Efcacy and Safety of Postoperative Adjuvant Hepatic Arterial Infusion Chemotherapy With mFOLFOX in Hepatocellular Carcinoma With High-risk Recurrence Factors [Phase 2]
This clinical trial update describes a Phase 2 study evaluating the efficacy and safety of postoperative adjuvant hepatic arterial infusion …
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Clinical trial update for DECOY20 with or without tislelizumab in adults with advanced solid tumors across Phase 1 and Phase 2. The listed i…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Long Term Prediction of MASH-related HCC Risk by Proteomics
A University Hospital, Bordeaux-sponsored study is examining long-term prediction of hepatocellular carcinoma risk in metabolic-associated s…