Hepatitis C
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CLINICAL_TRIALS research · 2013-07-25Clinical Trial Update: FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation
This document provides an update on the Fibroleukin (FGL2) trial for preventing hepatitis C virus recurrence after liver transplantation, wi…
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CLINICAL_TRIALS withdrawal · 2013-07-22Clinical Trial Update: Inflammation, Stress & Social Behavior: Using Ecological Assessments & Model Systems to Enhance Relevance to Health Outcomes [NA]
This University of Arizona clinical trial on inflammation, stress, and social behavior in Hepatitis C patients using ecological assessments …
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CLINICAL_TRIALS trial_result · 2013-07-19Clinical Trial Update: A Randomized Trial of Vaccine Adherence in Young Injection Drug Users [NA]
This completed randomized trial examined adherence to vaccination among young injection drug users, with results posted in 2013.
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CLINICAL_TRIALS withdrawal · 2013-07-18Clinical Trial Update: Japanese Bridging Study Conducted in the United States [Phase 1]
Bristol-Myers Squibb’s Phase 1 bridging trial for a Hepatitis C virus therapy conducted in the United States has been withdrawn.
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CLINICAL_TRIALS research · 2013-07-17Clinical Trial Update: Epidemiological Study to Evaluate Personality Disorders in Prison Populations in Treatment for Hepatitis C
An epidemiological trial update describing a study to evaluate the prevalence of personality disorders in prison populations treated for chr…
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CLINICAL_TRIALS trial_result · 2013-07-12Clinical Trial Update: An Exploratory Study of Telaprevir in Treatment-Naive Participants With Chronic Genotype 4 Hepatitis C Virus Infection [Phase 2]
An update on a Phase 2 exploratory trial of telaprevir in treatment-naive adults with chronic genotype 4 hepatitis C, with results posted.
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CLINICAL_TRIALS trial_result · 2013-07-11Clinical Trial Update: Trial Comparing the Efficacy, Tolerability and Safety Between Three Arms in Treatment of HCV in Egyptian Population [Phase 4]
This is a Phase 4 clinical trial update comparing three treatment arms for chronic hepatitis C in an Egyptian population; the available snip…
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CLINICAL_TRIALS trial_result · 2013-07-09Clinical Trial Update: Potential for Drug-drug Interactions Between Boceprevir and Etravirine in HIV/Hepatitis C Virus Negative Volunteers [NA]
Completed trial evaluating potential drug-drug interactions between boceprevir and etravirine in HIV/Hepatitis C-negative volunteers.
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CLINICAL_TRIALS trial_result · 2013-07-05Clinical Trial Update: S-Adenosyl Methionine (SAMe) to Treat Patients With Chronic Hepatitis C [Phase 2]
A Phase 2 study sponsored by NIDDK evaluated S-Adenosyl Methionine (SAMe) for chronic hepatitis C; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-07-01Clinical Trial Update: PEDS-C: Pegylated Interferon +/- Ribavirin for Children With Hepatitis C [Phase 3]
Phase 3 trial update of PEDS-C evaluating pegylated interferon with or without ribavirin in children with chronic hepatitis C; study complet…
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CLINICAL_TRIALS withdrawal · 2013-07-01Clinical Trial Update: A Pilot Trial to Determine the Safety and Efficacy of Fluvastatin in Previous Partial Responders to Pegylated Interferon and Ribivirin in Patients With Genotype 1 Hepatitis C [Phase 2]
A Phase 2 pilot trial investigating the safety and efficacy of fluvastatin in genotype 1 hepatitis C patients who previously partially respo…
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CLINICAL_TRIALS trial_result · 2013-06-28Clinical Trial Update: A Registration Study to Evaluate the Performance of CHIRON® RIBA® HCV 3.0 SIA in HCV Antibody Detection
A registration study evaluating the CHIRON RIBA HCV 3.0 SIA diagnostic for Hepatitis C antibody detection has been terminated in China. The …
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CLINICAL_TRIALS trial_result · 2013-06-24Clinical Trial Update: A Study of Combination Therapy With PEGASYS (Pegylated Interferon Alfa-2a (40KD)) and Copegus (Ribavirin) in Patients With Chronic Hepatitis C Genotype 2 or 3 Who Do Not Achieve a Rapid Viral Response [Phase 3]
Phase 3 study assessing the combination of Pegasys (pegylated interferon alfa-2a) and Copegus (ribavirin) in patients with chronic hepatitis…
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CLINICAL_TRIALS withdrawal · 2013-06-21Clinical Trial Update: Multiple Ascending Dose Study of BMS-929075 in Hepatitis C Virus (HCV) Infected Patients [Phase 1]
A Phase 1 multiple ascending dose study of BMS-929075 in patients with chronic hepatitis C has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-06-11Clinical Trial Update: Prediction of Hepatitis C Recurrence in Liver Transplant Recipients
A clinical trial evaluating the prediction of hepatitis C recurrence after liver transplantation was terminated.
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CLINICAL_TRIALS trial_result · 2013-06-05Clinical Trial Update: Pharmacokinetic Study of BMS-914143 in Participants With Normal Renal Function and Mild, Moderate, Severe and End-stage Renal Dysfunction [Phase 1]
Phase 1 pharmacokinetic study of BMS-914143 in participants with normal renal function and mild to end-stage renal dysfunction; the study ha…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: A Phase 2a Study to Evaluate Viral Kinetics and Safety of Telaprevir in Participants With Genotype 2 or 3 Hepatitis C Infection [Phase 2]
A Phase 2a study evaluating the viral kinetics and safety of telaprevir in participants with genotype 2 or 3 hepatitis C infection is comple…
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CLINICAL_TRIALS trial_result · 2013-06-03Clinical Trial Update: Pharmacogenomic Research in Korean Patients With Hepatitis C
Clinical trial update noting the completion of a pharmacogenomic study in Korean patients with chronic hepatitis C.
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CLINICAL_TRIALS trial_result · 2013-05-30Clinical Trial Update: Feasibility of a Hepatitis C Virus (HCV) Decision-Making Intervention Among HIV-infected Adults [NA]
A completed clinical trial evaluating the feasibility of a Hepatitis C decision-making intervention in HIV-infected adults.
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CLINICAL_TRIALS trial_result · 2013-05-17Clinical Trial Update: Pilot Study to Assess Gut Mucosal B Cells in Individuals With HCV and HIV
This pilot trial evaluating gut mucosal B cells in individuals with HIV infection and hepatitis C has been terminated.
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CLINICAL_TRIALS trial_result · 2013-05-15Clinical Trial Update: A Safety and Tolerability Study of Nitazoxanide in HIV-HCV Treatment Failures [Phase 1, Phase 2]
A safety and tolerability study of nitazoxanide in individuals with HIV and hepatitis C who failed prior treatment (Phase 1/2; completed wit…
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CLINICAL_TRIALS trial_result · 2013-05-06Clinical Trial Update: TMC435-TiDP16-C125 - Study in Healthy Volunteers to Evaluate the Potential of TMC435 to Increase the Sensitivity of the Skin Towards Exposure to Sun Light [Phase 1]
Phase 1 study in healthy volunteers to evaluate whether TMC435 increases sensitivity of the skin to sunlight; the trial is completed.
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CLINICAL_TRIALS trial_result · 2013-05-06Clinical Trial Update: TMC435-TiDP16-C117: The Effect of TMC435 on the Results of Electrocardiograms (Electric Recording of the Heart) in Healthy Volunteers [Phase 1]
A Phase 1 study examining whether TMC435 affects electrocardiogram results in healthy volunteers to assess cardiac safety.
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Efficacy of Nitazoxanide in the Treatment of Chronic Hepatitis C Virus (HCV) [Phase 2, Phase 3]
This document reports results from Phase 2 and Phase 3 trials of nitazoxanide for chronic hepatitis C. Results were posted in May 2013.
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CLINICAL_TRIALS trial_result · 2013-05-01Clinical Trial Update: An Open-Label Study of Telaprevir Administered Every 12 or 8 Hours in Combination With One of Two Pegylated Interferons and Ribavirin in Treatment-Naive Genotype 1 Chronic Hepatitis C Participants [Phase 2]
This open-label Phase 2 study evaluated telaprevir dosed every 12 or 8 hours in combination with one of two pegylated interferons and ribavi…