Hepatitis C
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: Supporting Treatment Outcomes Among PWID [NA]
A Johns Hopkins–sponsored clinical trial on treatment outcomes among people who inject drugs with Hepatitis C and HIV coinfection has comple…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Study to Evaluate Adverse Events and Change in Disease Activity in Adult and Adolescent Participants With Acute Hepatitis C Virus (HCV) Infection on Treatment With Oral Tablets of Glecaprevir (GLE)/Pibrentasvir (PIB) [Phase 3]
Phase 3 trial update evaluating adverse events and change in disease activity in adults and adolescents with acute hepatitis C treated with …
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Lung Transplant HCV, Pilot Study [EARLY_Phase 1]
An early Phase 1 clinical trial in Toronto is evaluating treatment related to lung transplant infection and hepatitis C. The study is curren…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Single-Cell Profiling of Liver-infiltrating Immune Cells of Patients with NASH- and Virus-related HCC: Implications for Immunotherapy
A completed single-cell profiling study of liver-infiltrating immune cells in hepatocellular carcinoma associated with MASLD or hepatitis C …
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: HEPATITIS C SCREENING in ADULTS with RISK FACTORS in FIVE CITIES of COLOMBIA'S CARIBBEAN COAST (FIVE-CC)
This document announces an upcoming hepatitis C screening study in adults with risk factors across five cities on Colombia's Caribbean coast…
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: HCV and Co-morbid Alcohol Use Disorders: A Translational Investigation of Antiviral Therapy Outcomes on CNS Function
A translational clinical trial assessing CNS outcomes of Hepatitis C antiviral therapy in patients with alcohol use disorder has completed. …
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Switching Regimen in Treating Cirrhotic HCV GT1b Subjects [Phase 2]
Phase 2 clinical trial updating switching regimens for cirrhotic patients with chronic hepatitis C infection genotype 1b; the study has comp…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Treating Hepatitis C in Pakistan. Strategies to Avoid Resistance to Antiviral Drugs
This clinical trial update discusses approaches to treating chronic Hepatitis C in Pakistan and outlines strategies to prevent antiviral dru…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Follow up of IFN Vs DAAs HCV SVR (IFDACS Study)
This document reports follow-up results from the IFDACS study comparing interferon-based therapy to direct-acting antivirals in chronic hepa…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Treatment of HIV/HCV Coinfection With Peg-IFN and Ribavirin in Patients Receiving ART Monotherapy With Lopinavir/r [Phase 4]
Phase 4 clinical trial update on treating HIV/HCV coinfection with Pegylated interferon and ribavirin in patients on lopinavir/ritonavir-bas…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Partner Navigation Intervention for Hepatitis C Treatment Among Young People Who Inject Drugs [NA]
This document reports an ongoing clinical trial evaluating a partner navigation intervention to improve Hepatitis C treatment among young pe…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: 8- Versus 12-week of Sofosbuvir-ravidasvir Treatment of Chronic Hepatitis C [Phase 2, Phase 3]
Completed Phase 2/3 clinical trial comparing 8-week versus 12-week regimens of sofosbuvir-ravidasvir for chronic Hepatitis C. The snippet do…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Radomised Phase II Study of MTL-CEBPA Plus Sorafenib or Sorafenib Alone [Phase 2]
Randomized Phase II trial comparing MTL-CEBPA plus Sorafenib to Sorafenib alone in hepatocellular carcinoma; the study includes patients wit…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: DBS TaT in Peer-assisted Telemedicine for Hepatitis C [NA]
A clinical trial sponsored by Oregon Health and Science University explores DBS TaT in peer-assisted telemedicine for Hepatitis C. The study…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Non-interventional Study to Assess the Number of People With Untreated/Unknown HBV + HDV and HCV in South-East Austria
Non-interventional study in Southeast Austria to estimate the number of people with untreated or unknown hepatitis B, hepatitis C, and hepat…
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Linkage to Care for Persons with Hep C Infection [NA]
The study completed an evaluation of linkage-to-care strategies for individuals with chronic hepatitis C, including participants with substa…
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Tools to Identify People At Risk or Already Infected with HIV and HCV [NA]
This clinical trial update describes tools to identify people at risk for HIV and hepatitis C infection or who are already infected.
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: HCV Test and Treat Utilizing Simplified HCV Patient Education [Phase 4]
Phase 4 clinical trial assessing a simplified HCV test-and-treat education approach was terminated.
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CLINICAL_TRIALS trial_result · 2025-02-26Clinical Trial Update: HepC Micro-elimination on MSM and TGW Population.
A completed clinical trial evaluating hepatitis C micro-elimination among men who have sex with men and transgender women, including conside…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Trial of Hepatitis C Self-Testing in the Hands of Untrained Lay Users [NA]
The Hepatitis C self-testing trial with untrained lay users has completed. The sponsor is bioLytical Laboratories.
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Impact of Direct-acting Antiviral Drugs on The Patterns of Gut Microbiota in Patients With HCV Related Chronic Liver Diseases
A completed clinical trial evaluating the effect of direct-acting antiviral drugs on gut microbiota in patients with hepatitis C–related chr…
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Hepatitis C Prevalence in Men Who Have Sex With Men
A completed clinical trial update reporting the prevalence of Hepatitis C in men who have sex with men.
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: The DETECT HCV Screening Trial [NA]
This clinical trials update reports that the DETECT HCV Screening Trial has completed.
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Bariatric Embolization of Arteries in Obese Patients With HCC to Allow Salvage Liver Transplantation [NA]
A clinical trial evaluating bariatric embolization of arteries in obese patients with hepatocellular carcinoma to enable salvage liver trans…
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CLINICAL_TRIALS withdrawal · 2025-02-03Clinical Trial Update: A Long Term Follow-up Study in Participants Treated in a Preceding Phase 2 or 3 Study With a Regimen Containing Odalasvir and AL-335 With or Without Simeprevir for the Treatment of Hepatitis C Virus (HCV) Infection [Phase 3]
This document reports a termination of a long-term follow-up Phase 3 study of a regimen containing odalasvir, AL-335, with or without simepr…