Hepatitis C
📧 Sign up to get email alerts when something new happens for Hepatitis C.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: A Study of TMC435 in Combination With Peginterferon Alfa-2A and Ribavirin for Hepatitis C Virus Genotype-1 Infected Patients Who Participated in a Control Group of a TMC435 Study [Phase 3]
This Phase 3 trial update notes the completion of a study evaluating TMC435 in combination with peginterferon alfa-2a and ribavirin in hepat…
-
CLINICAL_TRIALS trial_result · 2016-04-01Clinical Trial Update: Dutch Acute HCV in HIV Study (DAHHS) [Phase 2]
The Dutch Acute HCV in HIV Study (DAHHS), a Phase 2 trial, has completed enrollment with results posted in 2016.
-
CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: Efficacy of an Exercise Intervention to Decrease Depressive Symptoms in Veterans With Hepatitis C [NA]
A completed clinical trial evaluated whether an exercise program reduces depressive symptoms in veterans with hepatitis C.
-
CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Study of Efficacy and Safety of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Chronic Hepatitis C Participants With Child-Pugh (CP)-B Hepatic Insufficiency (MK-5172-059) [Phase 2, Phase 3]
Study evaluating the efficacy and safety of grazoprevir and elbasvir in chronic hepatitis C patients with Child-Pugh B hepatic insufficiency…
-
CLINICAL_TRIALS research · 2016-03-14Clinical Trial Update: Peripheral Blood Mononuclear Cell (PBMC) Gene Expression in HCV Genotype 1 Patients [Phase 4]
A Phase 4 study examining peripheral blood mononuclear cell gene expression in genotype 1 hepatitis C patients has been completed.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: An Observational Study on Long-Term Persistence of Resistant Mutations And Durability of Sustained Virological Response in Patients With Chronic Hepatitis C Treated With Direct Acting Antiviral (DAA)- Containing Regimens
This terminated observational study evaluated how long resistance mutations persist and whether sustained virologic response endures in pati…
-
CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Sofosbuvir/Simeprevir Plus a Flat Dose of Ribavirin in Genotype 1 Elderly HCV Cirrhotic Patients [Phase 4]
Phase 4 trial assessing sofosbuvir/simeprevir plus a flat dose of ribavirin in genotype 1 elderly patients with liver cirrhosis; the study i…
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: An Efficacy and Safety Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in the Treatment of Chronic Hepatitis C Virus in Participants Who Are Co-Infected With Human Immunodeficiency Virus:C-EDGE CO-INFXN (MK-5172-061) [Phase 3]
Phase 3 clinical trial evaluating grazoprevir plus elbasvir in chronic hepatitis C patients co-infected with HIV; study completed with poste…
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Study of Efficacy and Safety of Grazoprevir (MK-5172) + Elbasvir (MK-8742) With or Without Ribavirin for Participants With Hepatitis C Genotype 1, 4, or 6 Infections Who Have Failed Prior Treatment With Pegylated Interferon + Ribavirin (MK-5172-068) [Phase 3]
Phase 3 trial assessing efficacy and safety of grazoprevir/elbasvir with or without ribavirin in Hepatitis C Genotypes 1, 4, or 6 after prio…
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Grazoprevir (MK-5172) With Peg-Interferon and Ribavirin in Participants With Chronic Genotype 2 or 3 Hepatitis C (MK-5172-012) [Phase 2]
Phase 2 trial evaluating grazoprevir with peg-interferon and ribavirin for chronic hepatitis C genotype 2 or 3; the study was terminated and…
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) + Ribavirin in Participants With Chronic Hepatitis C Who Failed Prior Direct-Acting Antiviral Therapy (MK-5172-048) [Phase 2]
Phase 2 study evaluating Grazoprevir + Elbasvir + Ribavirin in Chronic Hepatitis C patients who failed prior direct-acting antivirals; study…
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: A Study of Different Durations of Treatment With Grazoprevir (MK-5172) in Combination With Ribavirin in Participants With Chronic Hepatitis C (MK-5172-039) [Phase 2]
Phase 2 trial evaluating different durations of Grazoprevir (MK-5172) with Ribavirin in chronic Hepatitis C patients; results posted after c…
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Efficacy and Safety of Combination Grazoprevir (MK-5172) + Elbasvir (MK-8742) + Ribavirin (RBV) in Genotype 2 Hepatitis C Infection (MK-5172-047) [Phase 2]
Phase 2 trial assessing the efficacy and safety of a Grazoprevir/Elbasvir plus Ribavirin regimen in genotype 2 Hepatitis C infection; comple…
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Copegus (Ribavirin) in Patients With Chronic Hepatitis C (CHC) Enrolled in a Methadone Maintenance Treatment Program. [Phase 4]
This Phase 4 clinical trial update reports completion and posted results for the combination of peginterferon alfa-2a and ribavirin in patie…
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Ledipasvir/Sofosbuvir Fixed-Dose Combination and Vedroprevir With or Without Ribavirin in Treatment-Experienced Participants With Chronic Genotype 1 HCV Infection and Cirrhosis [Phase 2]
Phase 2 trial evaluating fixed-dose Ledipasvir/Sofosbuvir with or without Vedroprevir (with or without ribavirin) in treatment-experienced c…
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: A Multiple Dose Study of Grazoprevir (MK-5172) in Hepatitis C-Infected Participants (MK-5172-010) [Phase 1]
Phase 1 multiple-dose study of Grazoprevir (MK-5172) in hepatitis C-infected participants has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: The Pharmacokinetics of Grazoprevir (MK-5172) and Elbasvir (MK-8742) in Participants With Renal Insufficiency (MK-5172-050) [Phase 1]
Phase 1 pharmacokinetic study evaluating grazoprevir and elbasvir in participants with renal impairment.
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: A Study of Different Doses of Grazoprevir (MK-5172) Given With Pegylated Interferon Alfa-2b and Ribavirin to Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-038) [Phase 2]
Phase 2 trial evaluating different doses of grazoprevir with pegylated interferon alfa-2b and ribavirin in treatment-naïve chronic hepatitis…
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: The SIM-SOF Trial for Hepatitis C [Phase 4]
This Phase 4 clinical trial update reports that the SIM-SOF trial in chronic hepatitis C has completed and results were posted.
-
CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Grazoprevir (MK-5172-013) [Phase 1]
Phase 1 study assessing how hepatic insufficiency affects pharmacokinetics of Grazoprevir (MK-5172-013) in Hepatitis C patients; completed w…
-
CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: Grazoprevir (MK-5172) Administered With Peginterferon and Ribavirin in Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-003) [Phase 2]
This entry reports the completion of a Phase 2 trial (MK-5172-003) evaluating Grazoprevir in combination with Peginterferon and Ribavirin in…
-
CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: A Prospective Study to Evaluate the Specificity of the Cobas TaqScreen MPX Test for Use on the Cobas s 201 System for Screening Plasma Pools From Source Plasma Donors for the Presence of HBV DNA, HCV RNA, and HIV-1 RNA [NA]
A prospective study evaluating the specificity of Roche's Cobas TaqScreen MPX test for detecting HBV DNA, HCV RNA, and HIV-1 RNA in plasma p…
-
CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: A Study of Grazoprevir (MK-5172) in Hepatitis C-Infected Male Participants (MK-5172-004) [Phase 1]
A Phase 1 study evaluating grazoprevir (MK-5172) in hepatitis C-infected male participants has completed, with results posted in 2016.
-
CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: Peginterferon Plus Ribavirin Combination Therapy for Hepatitis C Six Months After Onset of Acute Infection [Phase 4]
Phase 4 clinical trial evaluating pegylated interferon plus ribavirin for acute hepatitis C when started about six months after infection. T…
-
CLINICAL_TRIALS trial_result · 2016-03-01Clinical Trial Update: Triple DAAs Regimen in Treating Non-cirrhotic HCV GT1b Subjects [Phase 2]
Phase 2 trial update on a triple direct-acting antiviral regimen for non-cirrhotic hepatitis C genotype 1b patients and the study status ind…