Hepatitis C
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-06-20Clinical Trial Update: Ledipasvir/Sofosbuvir Fixed-Dose Combination Plus Ribavirin in Participants With Chronic HCV With Advanced Liver Disease or Post-Liver Transplant [Phase 2]
Phase 2 trial evaluating a fixed-dose combination of ledipasvir/sofosbuvir with ribavirin in chronic hepatitis C patients with advanced live…
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CLINICAL_TRIALS trial_result · 2016-06-17Clinical Trial Update: Endothelial Dysfunction and Subclinical Atheromatosis in Chronic HCV Infection. Response to DAA Agents. [Phase 4]
Phase 4 clinical trial update examining endothelial dysfunction and subclinical atheromatosis in chronic hepatitis C infection and the effec…
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CLINICAL_TRIALS trial_result · 2016-06-15Clinical Trial Update: PROPHESYS 1: An Observational Study on Predictors of Response in Treatment-naïve Patients With Chronic Hepatitis C Virus (HCV)Treated With Pegasys (Peginterferon Alfa-2a)
The PROPHESYS 1 study update describes predictors of response in treatment-naïve patients with chronic hepatitis C virus infection treated w…
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CLINICAL_TRIALS trial_result · 2016-06-14Clinical Trial Update: Study in Hepatitis C Virus (HCV) Infected Patients Undergoing Liver Transplantation to Evaluate a Human Monoclonal Antibody Against Hepatitis C [Phase 2]
A Phase 2 study evaluating a human monoclonal antibody against Hepatitis C in HCV-infected patients undergoing liver transplantation was ter…
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CLINICAL_TRIALS trial_result · 2016-06-14Clinical Trial Update: A Study of Induction Dosing With Peginterferon Alfa-2a and Ribavirin in Participants With Chronic Hepatitis C (CHC) Genotype 1 Infection [Phase 4]
Phase 4 trial evaluating induction dosing with peginterferon alfa-2a and ribavirin in chronic hepatitis C genotype 1; the study is completed…
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CLINICAL_TRIALS trial_result · 2016-06-10Clinical Trial Update: Drug Drug Interaction Study Between BI 201335 and BI 207127 in Chronic Hepatitis C Infected Patients [Phase 1]
Phase 1 study assessing drug-drug interaction between BI 201335 and BI 207127 in adults with chronic hepatitis C; results have been posted a…
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FDA approval · 2016-06-08FDA Approved: LEDIPASVIR AND SOFOSBUVIR — Supplemental Application (Asegua Therapeutics LLC)
FDA approved a supplemental application for Ledipasvir and Sofosbuvir from Asegua Therapeutics LLC.
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CLINICAL_TRIALS trial_result · 2016-06-08Clinical Trial Update: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Ribavirin in Patients With Chronic Hepatitis C (CHC) Previously Treated With PEG-Intron + Ribavirin [Phase 4]
Phase 4 study assessing PEGASYS (peginterferon alfa-2a 40KD) plus ribavirin in patients with chronic hepatitis C previously treated with PEG…
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CLINICAL_TRIALS trial_result · 2016-06-08Clinical Trial Update: A Study of Peginterferon Alfa-2a Plus Ribavirin in Early Non-Responder Participants With Chronic Hepatitis C (CHC) Genotype 1, 4, 5, and 6 [Phase 3]
Phase 3 study of peginterferon alfa-2a plus ribavirin in early non-responder participants with chronic hepatitis C (genotypes 1, 4, 5, and 6…
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CLINICAL_TRIALS research · 2016-06-07Clinical Trial Update: Mesenchymal Stem Cells Transplantation for Liver Cirrhosis Due to HCV Hepatitis [Phase 1, Phase 2]
This entry reports an ongoing Phase 1/Phase 2 clinical trial evaluating mesenchymal stem cell transplantation for liver cirrhosis caused by …
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CLINICAL_TRIALS trial_result · 2016-06-06Clinical Trial Update: Multiple Oral Doses of BI 207127 NA in Treatment naïve and Treatment-experienced Hepatitis C Virus (HCV)-Infected Patients [Phase 1]
Phase 1 study evaluating multiple oral doses of BI 207127 in treatment-naïve and treatment-experienced patients with chronic Hepatitis C. Re…
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Study Comparing Daclatasvir (BMS-790052) With Telaprevir Combined With Peginterferon Alfa-2a and Ribavirin in Patients With Chronic Hepatitis C Virus Infection [Phase 3]
A Phase 3 trial comparing daclatasvir to telaprevir combined with peginterferon alfa-2a and ribavirin in adults with chronic hepatitis C vir…
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CLINICAL_TRIALS withdrawal · 2016-06-03Clinical Trial Update: Impact of HCV Treatment on Neurocognitive Functions and Brain Metabolism [Phase 4]
Phase 4 trial evaluating the impact of hepatitis C treatment on neurocognitive function and brain metabolism has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-05-30Clinical Trial Update: Safety and Efficacy of Boceprevir/Peginterferon Alfa-2a/Ribavirin in Interleukin-28B CC Allele-Positive Chronic Hepatitis C Virus (HCV) Genotype 1 Participants (P07755) [Phase 3]
This phase 3 trial evaluated safety and efficacy of Boceprevir with Peginterferon alfa-2a and Ribavirin in IL-28B CC allele-positive chronic…
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CLINICAL_TRIALS trial_result · 2016-05-30Clinical Trial Update: A Study of the Combination Regimen Grazoprevir (MK-5172) and Elbasvir (MK-8742) ± Ribavirin in Participants With Chronic Hepatitis C (MK-5172-035) [Phase 2]
Phase 2 study evaluating Grazoprevir and Elbasvir with or without Ribavirin in chronic hepatitis C completed in 2016.
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EMA approval · 2016-05-27Two new combination therapies against chronic hepatitis C
The EMA announces two new combination therapies for chronic hepatitis C, expanding treatment options.
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Study of pegInterferon Alfa-2a, Ribavirin, and Daclatasvir (BMS-790052) With or Without BMS-650032 for Participants in Some Hepatitis C Virus Trials [Phase 2]
Phase 2 trial update reporting results for a study of peginterferon alfa-2a, ribavirin, and daclatasvir with or without BMS-650032 in hepati…
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CLINICAL_TRIALS trial_result · 2016-05-20Clinical Trial Update: Integrated Care for Patients With High Risk Substance Use and Psychiatric Disorder With Chronic Direct Acting Antiviral Treatment [NA]
A completed clinical trial evaluating integrated care for patients with high-risk substance use and psychiatric disorders undergoing chronic…
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: Determination of HCV Prevalence in a HIV Patient Cohort in Phnom Penh, Cambodia
A completed observational study assessing the prevalence of Hepatitis C infection among people living with HIV in Phnom Penh, Cambodia.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Study to Evaluate the Efficacy and Safety of ABT-450/Ritonavir/ABT- 267 (ABT-450/r/ABT-267) in Japanese Adults With Genotype 2 Chronic Hepatitis C Virus (HCV) Infection [Phase 3]
Phase 3 trial evaluating ABT-450/r/ABT-267 in Japanese adults with genotype 2 chronic HCV; study completed with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Brain Deficits in HIV/HCV Coinfected People Before and After Anti-HCV Therapy
Clinical trial update examining brain deficits in people coinfected with HIV and hepatitis C before and after anti-HCV therapy.
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Study of Ezetimibe for Chronic Hepatitis C Virus (HCV) Infection in Liver Transplant Candidates (EZE-2) [Phase 4]
Phase 4 trial evaluating ezetimibe for chronic hepatitis C in liver transplant candidates; current status is unknown.
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CLINICAL_TRIALS trial_result · 2016-05-10Clinical Trial Update: Evaluating the Effectiveness of Boceprevir, Pegylated-Interferon Alfa 2b and Ribavirin in Treating Hepatitis C Virus (HCV) Infection in Adults With HIV and HCV Infection [Phase 3]
Phase 3 trial evaluating boceprevir with pegylated interferon and ribavirin for HIV/HCV coinfection has completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: Effectiveness Of Daclatasvir-Based Regimens In Patients With Chronic Hepatitis C Infection In Europe: Experience From Named Patient Program And From Early Post-Marketing Authorization Period
This completed study evaluates the effectiveness of daclatasvir-based regimens for chronic hepatitis C in Europe, using data from a named-pa…
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: PROPHESYS 2: An Observational Study on Predictors of Response in Treatment-naïve Patients With Chronic Hepatitis C Treated With Pegasys (Peginterferon Alfa-2a) or Peginterferon-alfa-2b
An observational study in treatment-naïve chronic hepatitis C patients identifies predictors of response to pegylated interferon therapy (Pe…