Hepatitis C
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects [Phase 4]
Phase 4 study update reporting the single-dose pharmacokinetics of Suboxone in subjects with hepatic impairment.
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic Genotype 1 or 4 HCV and HIV-1 Co-infection [Phase 3]
Phase 3 trial evaluating the efficacy and safety of a fixed-dose combination of ledipasvir/sofosbuvir for 12 weeks in patients with chronic …
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: DVD-based HIV/HCV Prevention Intervention for Drug-Involved Latino Criminal Justice Clients [NA]
A completed clinical trial evaluating a DVD-based HIV/HCV prevention intervention for drug-involved Latino criminal-justice clients.
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CLINICAL_TRIALS trial_result · 2016-10-20Clinical Trial Update: DAA Based Therapy for Recently Acquired Hepatitis C (DARE-C) [Phase 4]
Phase 4 trial update on direct-acting antiviral–based therapy for recently acquired Hepatitis C, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: Randomized, Open-Label, Study to Evaluate the Safety and Efficacy of Sofosbuvir Tablet Plus Ribavirin Tablet (Part A) Versus Single Dose (2 Tablets) of EHCV Containing Sofosbuvir, Ribavirin, and Natural Anti-hemolytic (B) in Egyptian Adults With Chronic Genotype 4 HCV Infection [Phase 2, Phase 3]
Randomized, open-label Phase 2/3 study evaluating the safety and efficacy of Sofosbuvir plus Ribavirin versus EHCV containing Sofosbuvir, Ri…
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: Real-life Security and Efficacy of DAA-based Therapy in HCV/HIV-Coinfected Patients
This clinical trial update assesses the real-world safety and efficacy of direct-acting antiviral therapy for hepatitis C in patients coinfe…
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CLINICAL_TRIALS trial_result · 2016-10-14Clinical Trial Update: An Efficacy and Safety Study of a 8 or 12-Week Treatment Regimen of Simeprevir in Combination With Sofosbuvir in Treatment-Naive and Experienced Participants With Chronic Genotype 4 Hepatitis C Virus Infection [Phase 2]
Completed Phase 2 study evaluating 8- or 12-week regimens of simeprevir with sofosbuvir in treatment-naive and experienced adults with chron…
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: Alisporivir With RBV in Chronic Hepatitis C Genotype 2 and 3 Participants for Whom Interferon is Not an Option [Phase 2]
Phase 2 trial of alisporivir with ribavirin in chronic hepatitis C genotypes 2 and 3 patients who cannot take interferon; the study complete…
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CLINICAL_TRIALS withdrawal · 2016-10-13Clinical Trial Update: Safety, Tolerability, and Efficacy of 24 Weeks Simeprevir+Sofosbuvir for Chronic Hepatitis C Genotype 1 [Phase 4]
This clinical trial update reports that the Phase 4 study of simeprevir plus sofosbuvir for chronic hepatitis C genotype 1 has been withdraw…
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CLINICAL_TRIALS trial_result · 2016-10-11Clinical Trial Update: Study of Grazoprevir (MK-5172) and Elbasvir (MK-8742) in Japanese Participants With Chronic Hepatitis C (MK-5172-058) [Phase 2, Phase 3]
Phase 2/3 trial update of grazoprevir and elbasvir in Japanese participants with chronic hepatitis C has completed with results posted in 20…
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EMA withdrawal · 2016-10-06EMA Expired: Incivo (telaprevir) — Janssen-Cilag International N.V.
The EMA page indicates that Incivo (telaprevir) has expired status, associated with chronic hepatitis C, indicating discontinuation or marke…
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CLINICAL_TRIALS trial_result · 2016-10-03Clinical Trial Update: Efficacy and Safety of MP-424, Peginterferon Alfa-2a (PEG-IFN Alfa-2a), and Ribavirin(RBV) in Treatment-Naïve or Relapsed Hepatitis C [Phase 3]
A Phase 3 trial evaluated the efficacy and safety of MP-424 in combination with peginterferon alfa-2a and ribavirin in treatment-naïve or re…
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Efficacy and Safety of Alisporivir Triple Therapy in Chronic Hepatitis C Genotype 1 Treatment-naïve Participants [Phase 3]
Phase 3 trial results for alisporivir-based triple therapy in treatment-naïve chronic hepatitis C genotype 1 patients have been completed. R…
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CLINICAL_TRIALS research · 2016-09-29Clinical Trial Update: Direct Antiviral Agents for Hepatitis C Virus-associated Cryoglobulinaemia Vasculitis
This clinical trial update discusses the use of direct-acting antivirals to treat hepatitis C virus–associated cryoglobulinemic vasculitis; …
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: Implementation of a Sexual Health Intervention for Young Men Who Have Sex With Men (MSM) in Two Vietnamese Cities [NA]
This completed clinical trial evaluated the implementation of a sexual health intervention for young men who have sex with men (MSM) in two …
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: The Predictive Value of On-treatment Virological Response for Sustained Virological Response in Chronic Hepatitis C
This completed clinical trial assesses whether on-treatment virological response can predict sustained virological response in people with c…
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CLINICAL_TRIALS research · 2016-09-26Clinical Trial Update: A Retrospective Study to Assess the Impact of the Use of Interferon in Patients With Chronic Hepatitis C (DECISION)
A retrospective study assessed the impact of interferon therapy in patients with chronic Hepatitis C; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-09-26Clinical Trial Update: Hepatitis C in Clinically Discordant Hemophilic Siblings
A completed clinical trial update from UNC Chapel Hill reports on Hepatitis C infection in clinically discordant siblings with Hemophilia A.
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Observational Study Evaluating the Quality of Pegylated Interferon Alfa-2a and Ribavirin Treatment for Chronic Hepatitis C in Cooperation With the BNG (Association of German Resident Gastroenterologists)
An observational study evaluating pegylated interferon alfa-2a and ribavirin for chronic hepatitis C, with results posted after completion.
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: Raltegravir Switch Study to Reduce Liver Fibrosis Progression in HIV-Hepatitis C Co-infection [Phase 2]
Phase 2 trial evaluating switching to raltegravir to reduce liver fibrosis progression in HIV and Hepatitis C co-infected patients has compl…
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: Herpes Simplex Type 1 Suppression in Hepatitis C [Phase 2]
Phase 2 clinical trial evaluating suppression of herpes simplex virus type 1 in patients with chronic hepatitis C infection. The study compl…
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: A Study of TMC435 Plus Pegylated Interferon Alfa-2a and Ribavirin in Participants With Chronic HCV Infection [Phase 3]
Phase 3 study evaluating simeprevir (TMC435) in combination with pegylated interferon alfa-2a and ribavirin for chronic hepatitis C infectio…
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CLINICAL_TRIALS research · 2016-09-21Clinical Trial Update: Immune Monitoring of Hepatitis C Under DAA Therapy
This document provides an update on an ongoing clinical trial evaluating immune monitoring in hepatitis C patients undergoing direct-acting …
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CLINICAL_TRIALS trial_result · 2016-09-16Clinical Trial Update: Efficacy and Safety of Sofosbuvir Containing Regimens for the Treatment of Chronic HCV Infection in Participants With Chronic Genotype 1, 2, 3, or 6 HCV Infection [Phase 2]
Phase 2 clinical trial update evaluating sofobuvir-containing regimens for chronic Hepatitis C across genotypes 1–6; results posted after co…
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CLINICAL_TRIALS trial_result · 2016-09-16Clinical Trial Update: Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Adults With Chronic HCV Infection [Phase 3]
Phase 3 trial update of Sofosbuvir/Velpatasvir fixed-dose combination for 12 weeks in adults with chronic hepatitis C infection.