Hepatitis C

• CLINICAL_TRIALS trial_result · 2017-04-27
  Clinical Trial Update: Drug Interaction Study With Ribavirin and Abacavir in Male Subjects With Hepatitis C Who Have Failed Ribavirin Treatment [Phase 1]

  Phase 1 trial update on a drug interaction study between ribavirin and abacavir in male hepatitis C patients who previously failed ribavirin…

• CLINICAL_TRIALS trial_result · 2017-04-25
  Clinical Trial Update: Impact of Interleukin 28B (rs12979860) Genotype on Virological Responses Chronic Hepatitis C Treatment [Phase 3]

  A Phase 3 trial evaluated how IL-28B rs12979860 genotype influences virological response in chronic Hepatitis C treatment; the study has bee…

• CLINICAL_TRIALS trial_result · 2017-04-24
  Clinical Trial Update: A Study of Mericitabine in Combination With Telaprevir and Peginterferon Alfa-2a / Ribavirin in Participants With Chronic Hepatitis C [Phase 2]

  Phase 2 study evaluating Mericitabine in combination with Telaprevir and Peginterferon alfa-2a plus Ribavirin in participants with chronic H…

• CLINICAL_TRIALS trial_result · 2017-04-19
  Clinical Trial Update: A Phase 3 Evaluation of Daclatasvir and Asunaprevir in Treatment-naive Subjects With Chronic Hepatitis C Genotype 1b Infection [Phase 3]

  A Phase 3 trial evaluating the fixed-dose combination of daclatasvir and asunaprevir in treatment-naive adults with chronic hepatitis C geno…

• CLINICAL_TRIALS trial_result · 2017-04-18
  Clinical Trial Update: Safety, Metabolism, and Antioxidant Activity of Silymarin and Green Tea Extract in Patients With Chronic Hepatitis C [Phase 1]

  Phase 1 study assessing safety, metabolism, and antioxidant activity of silymarin and green tea extract in patients with chronic hepatitis C…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• CLINICAL_TRIALS trial_result · 2017-04-13
  Clinical Trial Update: Safety, Tolerability, and Efficacy of Asunaprevir and Daclatasvir in Subjects Coinfected With HIV-HCV [Phase 2]

  Phase 2 study evaluating safety, tolerability, and efficacy of asunaprevir combined with daclatasvir in HIV-HCV coinfected subjects. The tri…

• CLINICAL_TRIALS trial_result · 2017-04-12
  Clinical Trial Update: Open Label Trial of PEG-IFN, RBV & TVR vs. PEG-IFN & RBV Alone in Tx of HCV-1 in HIV-1 Co-infected Patients (CHAT) [Phase 3]

  Phase 3 open-label trial comparing telaprevir added to pegylated interferon and ribavirin versus pegylated interferon and ribavirin alone in…

• CLINICAL_TRIALS trial_result · 2017-04-12
  Clinical Trial Update: the Effect of Grazoprevir/Elbasvir and TACE vs. TACE Alone in Prolonging Survival of Patients With Non-resectable HCV Associated HCC. [NA]

  This clinical trial compares Grazoprevir/Elbasvir plus TACE to TACE alone in patients with non-resectable HCV-associated hepatocellular carc…

• CLINICAL_TRIALS trial_result · 2017-04-12
  Clinical Trial Update: Safety and Effect of Elbasvir/Grazoprevir Combination Therapy in Hemodialysis Patients With Chronic Hepatitis C [Phase 4]

  Phase 4 clinical trial update assessing the safety and effectiveness of the elbasvir/grazoprevir combination in hemodialysis patients with c…

• CLINICAL_TRIALS trial_result · 2017-04-12
  Clinical Trial Update: An Observational Study of Peginterferon Alfa-2a in Combination With Ribavirin in Participants With Chronic Hepatitis C and Compensated Liver Cirrhosis

  An observational study evaluating the safety and outcomes of peginterferon alfa-2a in combination with ribavirin in adults with chronic hepa…

• CLINICAL_TRIALS trial_result · 2017-04-12
  Clinical Trial Update: Biomarkers of Liver Fibrosis

  A clinical trial investigating biomarkers of liver fibrosis in hepatitis C has been terminated.

• CLINICAL_TRIALS trial_result · 2017-04-11
  Clinical Trial Update: Combination Therapy for Chronic Hepatitis C Infection [Phase 2]

  A Phase 2 clinical trial evaluating a combination therapy for chronic hepatitis C infection has completed; results were posted in 2017.

• CLINICAL_TRIALS trial_result · 2017-04-11
  Clinical Trial Update: Romiplostim in Treating Hepatitis C-Infected Patients With Thrombocytopenia [Phase 2]

  A Phase 2 trial evaluating romiplostim for thrombocytopenia in hepatitis C-infected patients was terminated.

• CLINICAL_TRIALS research · 2017-04-10
  Clinical Trial Update: Investigative Mathematical Modeling of Hospital Transmission of Hepatitis C

  Investigative update on a clinical trial using mathematical modeling to study hospital transmission of Hepatitis C.

• FDA approval · 2017-04-07
  FDA Approved: LEDIPASVIR AND SOFOSBUVIR — Supplemental Application (Asegua Therapeutics LLC)

  The FDA approved a supplemental application for ledipasvir and sofosbuvir (Asegua Therapeutics LLC).

• CLINICAL_TRIALS trial_result · 2017-04-06
  Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Co-administration of ABT-493 and ABT-530 With and Without Ribavirin in Subjects With HCV Genotype 1, 4, 5, and 6 Infection [Phase 2]

  Phase 2 trial assessing ABT-493 and ABT-530 with/without ribavirin in HCV genotypes 1, 4, 5, and 6; completed with results posted in 2017.

• CLINICAL_TRIALS research · 2017-04-05
  Clinical Trial Update: A Trial to Evaluate Safety, Tolerability, PK and Antiviral Activity of MB-110 in Hepatitis C Virus Infected Patients [Phase 1]

  Phase 1 clinical trial evaluating safety, tolerability, pharmacokinetics and antiviral activity of MB-110 in patients with Hepatitis C.

• CLINICAL_TRIALS trial_result · 2017-03-31
  Clinical Trial Update: Safety, Tolerability, and Antiviral Activity of ANA598 Administered in Combination With Pegylated Interferon and Ribavirin for the Treatment of Genotype-1 Chronic HCV Infection [Phase 2]

  A Phase 2 trial evaluated the safety, tolerability, and antiviral activity of ANA598 when given with pegylated interferon and ribavirin in g…

• CLINICAL_TRIALS trial_result · 2017-03-30
  Clinical Trial Update: An Observational Study on Dual And Triple Therapies Based on Peginterferon Alfa (e.g. Pegasys) in Patients With Chronic Hepatitis C

  Observational study evaluating dual and triple therapy regimens based on pegylated interferon alfa (Pegasys) in patients with chronic hepati…

• CLINICAL_TRIALS trial_result · 2017-03-28
  Clinical Trial Update: Relative Bioavailability Study of Ribavirin 200 Capsules and Rebetol 200 mg Capsules in Females Under Fasting Conditions [Phase 1]

  Phase 1 study evaluating the relative bioavailability of Ribavirin 200 capsules versus Rebetol 200 mg capsules in fasting female participant…

• CLINICAL_TRIALS trial_result · 2017-03-28
  Clinical Trial Update: Relative Bioavailability Study of Ribavirin 200 Capsules and Rebetol 200 mg Capsules in Females Under Non-Fasting Conditions [Phase 1]

  A Phase 1 relative bioavailability study comparing Ribavirin 200 mg capsules with Rebetol 200 mg capsules in females under non-fasting condi…

• CLINICAL_TRIALS trial_result · 2017-03-27
  Clinical Trial Update: Intravenous Silibinin in Combination With Peg-interferon and Ribavirin in Nonresponders [Phase 2]

  This document reports the completion of a Phase 2 trial evaluating intravenous silibinin in combination with pegylated interferon and ribavi…

• CLINICAL_TRIALS research · 2017-03-23
  Clinical Trial Update: The Prevalence and Severity of HCV Infection in Thalassemia Major and Thalassemia Intermedia in Siriraj Hospital

  A completed clinical study assessing the prevalence and severity of hepatitis C infection among patients with thalassemia major and thalasse…

• CLINICAL_TRIALS trial_result · 2017-03-20
  Clinical Trial Update: Peginterferon Alpha-2a Maintenance Therapy for Portal Hypertension in Patients With Hepatitis C [NA]

  Clinical trial update regarding pegylated interferon alfa-2a as maintenance therapy for portal hypertension in patients with hepatitis C; th…

• CLINICAL_TRIALS trial_result · 2017-03-20
  Clinical Trial Update: Trial of Peg-interferon Plus Epoetin-alfa for Treatment of Chronic Hepatitis C Virus Infection [Phase 3]

  A Phase 3 trial evaluating pegylated interferon alfa plus epoetin alfa for chronic hepatitis C has completed.